Plasma Adiponectin Does Not Correlate With Insulin Resistance and Cardiometabolic Variables in Nondiabetic Asian Indian Teenagers

OBJECTIVE—The objectives of this study were to determine age- and sex-specific concentrations of adiponectin in Asian Indian teenagers and adults and to assess whether its blood levels correlated with insulin resistance and other cardiometabolic parameters

Studies on maturity onset diabetes of the young (MODY) from S. India

We examined the following aspects of Maturity Onset Diabetes of the Young (MODY): prevalence, vascular complications, insulin secretion in offspring of MODY subjects, insulin resistance and whether MODY can be considered a distinct disease. We report a higher prevalence of MODY among Asian Indian patients. The prevalence rates of microvascular complications in MODY were found to be the same as in classical NIDDM patients. Glucose stimulated insulin and C-peptide responses were compared with non-diabetic controls. In MODY subjects, C-peptide responses were lower, whereas insulin responses were varied. Insulin secretion in offspring of MODY subjects was similarly evaluated, and abnormalities discovered even in these prediabetic subjects. Using the euglycaemic clamp technique, MODY patients were found to be more insulin resistant than classical NIDDM patients. Further lines of evidence are needed to resolve whether MODY can be considered a distinct disease

Experience with insulin pump treatment in Indian diabetics. A preliminary report

Six insulin-requiring diabetic subjects (five with resistant diabetes and one with bridle diabetes} were treated with continuous subcutaneous insulin infusion on a short-term basis. The blood sugar control was smoother and the insulin requirement was much lower than with conventional insulin therapy. The pump helped to break the insulin resistance in some cases. It is also helpful in the manaSemenl of brittle diabetes. It is an excellent toot in the management of problem patients with diabetes especially in the hospital setting

Abnormalities in insulin response to intravenous glucose in offspring of conjugal (Type 2) diabetic parents

Glucose and insulin responses were measured during intravenous glucose tolerance test in 12 normal controls and 16 normoglycaemic adult offspring of conjugal diabetic parents. The glucose response curve and the glucose disposal rate in the offspring were not different from the normal pattern. These subjects elicited a lower first phase insulin (0-10 minutes area under the curve, p = 0.04), lower peak immunoreactive insulin response (p = 0.032) and also showed a delay in the first phase (p = 0.037) compared to control values. The second phase of insulin (11-120 minutes area) was not significantly different in the two groups. These changes could serve as early markers of diabetes in offspring of conjugal diabetic parents

Pancreatic beta cell function and peripheral activity of insulin in maturity onset diabetics - evaluation by mathematical applications

Evaluation of the Pancreatic beta cell function and peripheral activity of insulin in diabetics were done using recently described mathematical formulae. Diabetics in general, had decreased beta cell function as well as impaired peripheral activity of insulin. In diabetics with ideal body weight, the chief defect was diminished insuling output which was directly proportional to the severity of diabetes. In obese diabetics, the main defect was at the periphery, and except in those with severe diabetes, beta cell function was better maintained. Application of these mathematical formulae helps in a clearer understanding of the kinetics of insulin and pathogenesis of diabetes in various types of diabetics

High carbohydrate high fibre diet in diabetes

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Insulin antibodies in diabetic patients

This article does not have an abstract

Geospatial Artificial Intelligence (GeoAI): Applications in Health Care

GeoAI is a new emerging research area that refers to set of technologies that integrate AI technology with a diversity of GIS (Geographic Information System) techniques. The present study observed that GeoAI goes beyond current GIS expectations and into the domain of possibility in the not-too-distant future. This emerging interdisciplinary science will lead us to sustainable decisions and explore the most suitable solutions to the existing problems. GeoAI has the potential to transform current geography and geomatics programs by incorporating a GeoAI dimension into modern GIS curricula. In this review, we have studied the application GeoAI in various healthcare fields. GeoAI has the potential to revolutionize healthcare, public health, infectious disease control, disaster aid, and the achievements of Sustainable Development Goals (SDG). in healthcare, GeoAI can help with disease diagnosis, treatment planning, and resource allocation. In public health, it can aid in disease surveillance, emergency response planning, and identifying health disparities. In infectious disease control, GeoAI can help predict and track disease outbreaks and support vaccination campaigns. In disaster aid, GeoAI can provide real time data on environmental hazards and their impact on public health. In achieving Sustainable Development Goals, it can support in land use planning, urban development, and resource allocation to promote health and environmental sustainability. Overall GeoAI has the potential to transform multiple sectors and improve the well-being of populations worldwide