27,743 research outputs found
Electronic states in a magnetic quantum-dot molecule: phase transitions and spontaneous symmetry breaking
We show that a double quantum-dot system made of diluted magnetic
semiconductor behaves unlike usual molecules. In a semiconductor double quantum
dot or in a diatomic molecule, the ground state of a single carrier is
described by a symmetric orbital. In a magnetic material molecule, new ground
states with broken symmetry can appear due the competition between the
tunnelling and magnetic polaron energy. With decreasing temperature, the ground
state changes from the normal symmetric state to a state with spontaneously
broken symmetry. Interestingly, the symmetry of a magnetic molecule is
recovered at very low temperatures. A magnetic double quantum dot with
broken-symmetry phases can be used a voltage-controlled nanoscale memory cell.Comment: 4 pages, 5 figure
Comment on ``Enhancement of the Tunneling Density of States in Tomonaga-Luttinger Liquids''
In a recent Physical Review Letter, Oreg and Finkel'stein (OF) have
calculated the electron density of states (DOS) for tunneling into a repulsive
Luttinger liquid close to the location of an impurity. The result of their
calculation is a DOS which is enhanced with respect to the pure system, and
moreover diverging for not too strong repulsion. In this Comment we intend to
show that OF's calculation suffers from a subtle flaw which, being corrected,
results into a DOS not only vanishing at zero frequency but in fact suppressed
in comparison with the DOS of a pure Luttinger liquid.Comment: 1 page, Revte
Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors
Microwave irradiation of 2-halobenzonitriles and methyl thioglycolate in the presence of triethylamine in DMSO at 130 °C provides rapid access to 3-aminobenzo[b]thiophenes in 58–96% yield. This transformation has been applied in the synthesis of the thieno[2,3-b]pyridine core motif of LIMK1 inhibitors, the benzo[4,5]thieno[3,2-e][1,4]diazepin-5(2H)-one scaffold of MK2 inhibitors and a benzo[4,5]thieno[3,2-d]pyrimidin-4-one inhibitor of the PIM kinases
On the Detection of Supermassive Primordial Stars. II. Blue Supergiants
Supermassive primordial stars in hot, atomically-cooling haloes at
15 - 20 may have given birth to the first quasars in the universe. Most
simulations of these rapidly accreting stars suggest that they are red, cool
hypergiants, but more recent models indicate that some may have been bluer and
hotter, with surface temperatures of 20,000 - 40,000 K. These stars have
spectral features that are quite distinct from those of cooler stars and may
have different detection limits in the near infrared (NIR) today. Here, we
present spectra and AB magnitudes for hot, blue supermassive primordial stars
calculated with the TLUSTY and CLOUDY codes. We find that photometric
detections of these stars by the James Webb Space Telescope (JWST) will be
limited to 10 - 12, lower redshifts than those at which red stars
can be found, because of quenching by their accretion envelopes. With moderate
gravitational lensing, Euclid and the Wide-Field Infrared Space Telescope
(WFIRST) could detect blue supermassive stars out to similar redshifts in
wide-field surveys.Comment: 9 pages, 5 figures, accepted by MNRA
Bayesian Image Quality Transfer with CNNs: Exploring Uncertainty in dMRI Super-Resolution
In this work, we investigate the value of uncertainty modeling in 3D
super-resolution with convolutional neural networks (CNNs). Deep learning has
shown success in a plethora of medical image transformation problems, such as
super-resolution (SR) and image synthesis. However, the highly ill-posed nature
of such problems results in inevitable ambiguity in the learning of networks.
We propose to account for intrinsic uncertainty through a per-patch
heteroscedastic noise model and for parameter uncertainty through approximate
Bayesian inference in the form of variational dropout. We show that the
combined benefits of both lead to the state-of-the-art performance SR of
diffusion MR brain images in terms of errors compared to ground truth. We
further show that the reduced error scores produce tangible benefits in
downstream tractography. In addition, the probabilistic nature of the methods
naturally confers a mechanism to quantify uncertainty over the super-resolved
output. We demonstrate through experiments on both healthy and pathological
brains the potential utility of such an uncertainty measure in the risk
assessment of the super-resolved images for subsequent clinical use.Comment: Accepted paper at MICCAI 201
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