155 research outputs found
Intracameral dexamethasone reduces inflammation on the first postoperative day after cataract surgery in eyes with and without glaucoma
Purpose: To evaluate whether dexamethasone injected intracamerally at the conclusion of surgery can safely and effectively reduce postoperative inflammation and improve surgical outcomes in eyes with and without glaucoma. Methods: Retrospective chart review of 176 consecutive eyes from 146 patients receiving uncomplicated phacoemulsification (PE) (n = 118 total, 82 with glaucoma), glaucoma drainage device (GDD) (n = 35), combined PE/GDD (n = 11) and combined PE/endoscopic cyclophotocoagulation (n = 12). Ninety-one eyes from 76 patients were injected with 0.4 mg dexamethasone intracamerally at the conclusion of surgery. All eyes received standard postoperative prednisolone and ketorolac eyedrops. Outcomes were measured for four to eight weeks by subjective complaints, visual acuity (VA), slit-lamp biomicroscopy, intraocular pressure (IOP) and postoperative complications. Results: Dexamethasone significantly reduced the odds of having an increased anterior chamber (AC) cell score after PE (p = 0.0013). Mean AC cell score ± SD in nonglaucomatous eyes was 1.3 ± 0.8 in control and 0.8 ± 0.7 with dexamethasone; scores in glaucomatous eyes were 1.3 ± 0.7 in control and 0.9 ± 0.8 with dexamethasone. Treated nonglaucomatous eyes had significantly fewer subjective complaints after PE (22.2% vs 64.7% in control; p = 0.0083). Dexamethasone had no significant effects on VA, corneal changes, IOP one day and one month after surgery, or long-term complications. Conclusions: Intracameral dexamethasone given at the end of cataract surgery significantly reduces postoperative AC cells in eyes with and without glaucoma, and improves subjective reports of recovery in nonglaucomatous eyes. There were no statistically significant risks of IOP elevation or other complications in glaucomatous eyes. © 2009 Chang et al, publisher and licensee Dove Medical Press Ltd
Electroweak Radiative Corrections To Polarized M{\o}ller Scattering Asymmetries
One loop electroweak radiative corrections to left-right parity violating
M{\o}ller scattering () asymmetries are presented. They
reduce the standard model (tree level) prediction by 40 \% where the
main shift and uncertainty stem from hadronic vacuum polarization loops. A
similar reduction also occurs for the electron-electron atomic parity violating
interaction. That effect can be attributed to an increase of
by in running from to 0. The
sensitivity of the asymmetry to ``new physics'' is also discussed.Comment: 14 pages, Revtex, postscript file including figures is available at
ftp://ttpux2.physik.uni-karlsruhe.de/ttp95-14/ttp95-14.ps or via WWW at
http://ttpux2.physik.uni-karlsruhe.de/cgi-bin/preprints/ (129.13.102.139
Atomic parity nonconservation and neutron radii in cesium isotopes
The interpretation of future precise experiments on atomic parity violation
in terms of parameters of the Standard Model could be hampered by uncertainties
in the atomic and nuclear structure. While the former can be overcome by
measurement in a series of isotopes, the nuclear structure requires knowledge
of the neutron density. We use the nuclear Hartree-Fock method, which includes
deformation effects, to calculate the proton and neutron densities in
{125}Cs-{139}Cs. We argue that the good agreement with the experimental charge
radii, binding energies, and ground state spins signifies that the
phenomenological nuclear force and the method of calculation that we use is
adequate. Based on this agreement, and on calculations involving different
effective interactions, we estimate the uncertainties in the differences of the
neutron radii delta_{N,N'} and conclude that they cause uncertainties in
the ratio of weak charges, the quantities determined in the atomic parity
nonconservation experiments, of less than 10^{-3}. Such an uncertainty is
smaller than the anticipated experimental error.Comment: 24 pages (RevTeX) 4 figures (Postscript/uuencoded compressed) Caltech
Preprint No. MAP-153 (March 1993
The anapole moment and nucleon weak interactions
From the recent measurement of parity nonconservation (PNC) in the Cs atom we
have extracted the constant of the nuclear spin dependent electron-nucleon PNC
interaction, ; the anapole moment constant, ; the strength of the PNC proton-nucleus potential, ; the -meson-nucleon interaction constant,
; and the strength of the neutron-nucleus potential, .Comment: Uses RevTex, 12 pages. We have added an explanation of the effect of
finite nuclear siz
Atomic Parity Violation and Precision Electroweak Physics - An Updated Analysis
A new analysis of parity violation in atomic cesium has led to the improved
value of the weak charge, . The implications
of this result for constraining the Peskin-Takeuchi parameters S and T and for
guiding searches for new Z bosons are discussed.Comment: 8 pages, LaTeX, 3 figures, Submitted to Physical Review D. Updated
experimental inputs and references; clarification of notatio
A Comprehensive Study of Leptoquark Bounds
We make a comprehensive study of indirect bounds on scalar leptoquarks that
couple chirally and diagonally to the first generation by examining available
data from low energy experiments as well as from high energy e+ e- and p pbar
accelerators. The strongest bounds turn out to arise from low energy data: For
leptoquarks that couple to right--handed quarks, the most stringent bound comes
from atomic parity violation. For leptoquarks that couple to left--handed
quarks, there are two mass regions: At low masses the bounds arise from atomic
parity violation or from universality in leptonic pi decays. At masses above a
few hundred GeV's, the dominant bounds come from the FCNC processes that are
unavoidable in these leptoquarks: The FCNC bound of the up sector, that arises
from D-Dbar mixing, combines with the FCNC bounds from the down sector, that
arise from rare K decays and K-Kbar mixing, to a bound on the flavour
CONSERVING coupling to the first generation.
The bounds restrict leptoquarks that couple with electromagnetic strength to
lie above 600 GeV or 630 GeV for leptoquarks that couple to RH quarks, and
above 1040 GeV, 440 GeV, and 750 GeV for the SU(2)_W scalar, doublet and
triplet leptoquarks that couple to LH quarks. These bounds are considerably
stronger than the first results from the direct searches at HERA. Our bounds
also already exclude large regions in the parameter space that could be
examined by various methods proposed for indirect leptoquark searches.Comment: 23 Pages (LaTeX), including 3 uufiled postscript figures.
WIS--93/90/Sept--PH. To appear in PRD. Changes: updated numbers ---> stronger
bound
Atomic Parity Nonconservation: Electroweak Parameters and Nuclear Structure
There have been suggestions to measure atomic parity nonconservation (PNC)
along an isotopic chain, by taking ratios of observables in order to cancel
complicated atomic structure effects. Precise atomic PNC measurements could
make a significant contribution to tests of the Standard Model at the level of
one loop radiative corrections. However, the results also depend upon certain
features of nuclear structure, such as the spatial distribution of neutrons in
the nucleus. To examine the sensitivity to nuclear structure, we consider the
case of Pb isotopes using various recent relativistic and non-relativistic
nuclear model calculations. Contributions from nucleon internal weak structure
are included, but found to be fairly negligible. The spread among present
models in predicted sizes of nuclear structure effects may preclude using Pb
isotope ratios to test the Standard Model at better than a one percent level,
unless there are adequate independent tests of the nuclear models by various
alternative strong and electroweak nuclear probes. On the other hand,
sufficiently accurate atomic PNC experiments would provide a unique method to
measure neutron distributions in heavy nuclei.Comment: 44 pages, INT Preprint DOE/ER/40561-050-INT92-00-1
Bounding Anomalous Gauge-Boson Couplings
In this version we have corrected some minor errors in the tables, corrected
typos, and added a reference. We have also updated our comparison with earlier
workers. Figures are now included as uuencoded compressed tar files.Comment: 32 page
Comparative study of the stability of bimatoprost 0.03% and latanoprost 0.005%: A patient-use study
<p>Abstract</p> <p>Background</p> <p>The stability of ophthalmic preparations in multidose containers is influenced by the preservative as well as the stability of the active ingredient. Unstable drugs may require refrigeration to preserve their active ingredient level and they are more likely to degrade over time, therefore becoming more susceptible to degradation based on patient mishandling. The purpose of this study was to determine the degree of molecular degradation that occurs in bimatoprost and latanoprost in a patient-use setting.</p> <p>Methods</p> <p>This was an open-label, laboratory evaluation of the relative stability of bimatoprost and latanoprost. Patients presently using bimatoprost (n = 31) or latanoprost (n = 34) were identified at 2 clinical sites in Brazil. Patients were instructed to use and store their drops as usual and return all used medication bottles between day 28 and day 34 after opening.</p> <p>Results</p> <p>Bimatoprost demonstrated no degradation, but latanoprost degraded at various levels. The mean age of bimatoprost was 43.0 ± 3.4 days and the mean age of latanoprost was 43.9 ± 2.8 days (P = .072). The mean percentage of labeled concentration was 103.7% in the bimatoprost bottles and 88.1% in the latanoprost bottles (P < 001).</p> <p>Conclusion</p> <p>This study showed that bimatoprost maintained â„100% concentration throughout the study period while latanoprost did not.</p
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