2,009 research outputs found
Microsurgical Technique of Simultaneous Pancreas/Kidney Transplantation in the Rat: Clinical Experience and Review of the Literature
Background: For experimental basic research, standardized transplantation models reflecting technical and immunologic aspects are necessary. This article describes an experimental model of combined pancreas/kidney transplantation (PKTx) in detail. Materials and Methods: Donor rats underwent en bloc pancreatectomy and nephrectomy. Revascularization was performed using the aorta with the superior mesenteric artery and the inferior vena cava with the portal vein. Exocrine drainage of the pancreas took place over a segment of the duodenum which was transplanted side-to-side to the jejunum. The kidney vessels were transplanted end-to-side. The ureter was anastomosed by patch technique. Postoperatively, serum parameters were monitored daily. Biopsies for histopathology were taken on days 5, 8 and 12. Results: All 12 recipients survived the combined PKTx without serious surgical complications. One thrombosis of the portal vein led to organ failure. Blood glucose levels were normal by the 3rd postoperative day. The transplanted duodenal segment showed slight villous atrophy, and the kidneys were well perfused without vascular complications. The anastomosis between ureter and bladder was leakproof. Conclusions: Excellent graft function and survival rates can be achieved due to simplified operation technique and short operation time. It may thus have high clinical relevance to immunologic issues within the scope of basic research. Copyright (C) 2009 S. Karger AG, Base
Dynamical simulation of transport in one-dimensional quantum wires
Transport of single-channel spinless interacting fermions (Luttinger liquid)
through a barrier has been studied by numerically exact quantum Monte Carlo
methods. A novel stochastic integration over the real-time paths allows for
direct computation of nonequilibrium conductance and noise properties. We have
examined the low-temperature scaling of the conductance in the crossover region
between a very weak and an almost insulating barrier.Comment: REVTex, 4 pages, 2 uuencoded figures (submitted to Phys. Rev. Lett.
Correlation effects in MgO and CaO: Cohesive energies and lattice constants
A recently proposed computational scheme based on local increments has been
applied to the calculation of correlation contributions to the cohesive energy
of the CaO crystal. Using ab-initio quantum chemical methods for evaluating
individual increments, we obtain 80% of the difference between the experimental
and Hartree-Fock cohesive energies. Lattice constants corrected for correlation
effects deviate by less than 1% from experimental values, in the case of MgO
and CaO.Comment: LaTeX, 4 figure
Random Series and Discrete Path Integral methods: The Levy-Ciesielski implementation
We perform a thorough analysis of the relationship between discrete and
series representation path integral methods, which are the main numerical
techniques used in connection with the Feynman-Kac formula. First, a new
interpretation of the so-called standard discrete path integral methods is
derived by direct discretization of the Feynman-Kac formula. Second, we
consider a particular random series technique based upon the Levy-Ciesielski
representation of the Brownian bridge and analyze its main implementations,
namely the primitive, the partial averaging, and the reweighted versions. It is
shown that the n=2^k-1 subsequence of each of these methods can also be
interpreted as a discrete path integral method with appropriate short-time
approximations. We therefore establish a direct connection between the discrete
and the random series approaches. In the end, we give sharp estimates on the
rates of convergence of the partial averaging and the reweighted
Levy-Ciesielski random series approach for sufficiently smooth potentials. The
asymptotic rates of convergence are found to be O(1/n^2), in agreement with the
rates of convergence of the best standard discrete path integral techniques.Comment: 20 pages, 4 figures; the two equations before Eq. 14 are corrected;
other typos are remove
Cohesive properties of alkali halides
We calculate cohesive properties of LiF, NaF, KF, LiCl, NaCl, and KCl with
ab-initio quantum chemical methods. The coupled-cluster approach is used to
correct the Hartree-Fock crystal results for correlations and to systematically
improve cohesive energies, lattice constants and bulk moduli. After inclusion
of correlations, we recover 95-98 % of the total cohesive energies. The lattice
constants deviate from experiment by at most 1.1 %, bulk moduli by at most 8 %.
We also find good agreement for spectroscopic properties of the corresponding
diatomic molecules.Comment: LaTeX, 10 pages, 1 figure, accepted by Phys. Rev.
Primary Proton Spectrum of Cosmic Rays measured with Single Hadrons
The flux of cosmic-ray induced single hadrons near sea level has been
measured with the large hadron calorimeter of the KASCADE experiment. The
measurement corroborates former results obtained with detectors of smaller size
if the enlarged veto of the 304 m^2 calorimeter surface is encounted for. The
program CORSIKA/QGSJET is used to compute the cosmic-ray flux above the
atmosphere. Between E_0=300 GeV and 1 PeV the primary proton spectrum can be
described with a power law parametrized as
dJ/dE_0=(0.15+-0.03)*E_0^{-2.78+-0.03} m^-2 s^-1 sr^-1 TeV^-1. In the TeV
region the proton flux compares well with the results from recent measurements
of direct experiments.Comment: 13 pages, accepted by Astrophysical Journa
A New Interpretation of Flux Quantization
We study the effect of Aharonov-Bohm flux on the superconducting state in
metallic cylinders. Although Byers and Yang attributed flux quantization to the
flux-dependent minimum of kinetic energies of the Cooper pairs, it is shown
that kinetic energies do not produce any discernible oscillations in the free
energy of the superconducting state (relative to that of normal state) as a
function of the flux. This result is indeed anticipated by the observation of
persistent current in normal metal rings at low temperature. Instead, we have
found that pairing interaction depends on the flux, leading to flux
quantization. When the flux ) is given by (with
integer n), the pairing interaction and the free energy become unchanged (even
n) or almost unchanged (odd n), due to degenerate-state pairing resulting from
the energy level crossing. As a result, flux quantization and Little-Parks
oscillations follow.Comment: Revtex, 10 pages, 6 figures, For more information, send me an e-mail
at [email protected]
KCDC - The KASCADE Cosmic-ray Data Centre
KCDC, the KASCADE Cosmic-ray Data Centre, is a web portal, where data of
astroparticle physics experiments will be made available for the interested
public. The KASCADE experiment, financed by public money, was a large-area
detector for the measurement of high-energy cosmic rays via the detection of
air showers. KASCADE and its extension KASCADE-Grande stopped finally the
active data acquisition of all its components including the radio EAS
experiment LOPES end of 2012 after more than 20 years of data taking. In a
first release, with KCDC we provide to the public the measured and
reconstructed parameters of more than 160 million air showers. In addition,
KCDC provides the conceptional design, how the data can be treated and
processed so that they are also usable outside the community of experts in the
research field. Detailed educational examples make a use also possible for
high-school students and early stage researchers.Comment: 8 pages, accepted proceeding of the ECRS-symposium, Kiel, 201
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