4,280 research outputs found

    Spontaneous formation of a chiral (Mo2O2S2)2+-based cluster driven by dimeric {Te2O6}-based templates

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    Utilization of [Mo2S2O2(H2O)6]2+ and a tellurite anion led to the formation of three new clusters, 1–3, with unique structural features. The tellurite anion not only templated the formation of [(Mo2O2S2)4(TeO3)(OH)9]3− 1 and [(Mo2O2S2)12(TeO3)4(TeO4)2 (OH)18]10− 3, but also the in situ generation of two different types of dimeric {Te2O6} based moieties induced the spontaneous assembly of the chiral [(Mo2O2S2)10(TeO3)(Te2O6)2(OH)18]8− anionic cluster, 2

    Visual phototransduction components in cephalopod chromatophores suggest dermal photoreception

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    Author Posting. © The Author(s), 2015. This is the author's version of the work. It is posted here by permission of The Company of Biologists for personal use, not for redistribution. The definitive version was published in Journal of Experimental Biology 218 (2015): 1596-1602, doi: 10.1242/​jeb.117945.Cephalopod molluscs are renowned for their colorful and dynamic body patterns, produced by an assemblage of skin components that interact with light. These may include iridophores, leucophores, chromatophores, and (in some species) photophores. Here, we present molecular evidence suggesting that cephalopod chromatophores, small dermal pigmentary organs that reflect various colors of light, are photosensitive. RT-PCR revealed the presence of transcripts encoding rhodopsin and retinochrome within the retinas and skin of the squid Doryteuthis pealeii, and the cuttlefish Sepia officinalis and Sepia latimanus. In D. pealeii, Gqα and squid TRP channel transcripts were present in the retina and in all dermal samples. Rhodopsin, retinochrome, and Gqα transcripts were also found in RNA extracts from dissociated chromatophores isolated from D. pealeii dermal tissues. In D. pealeii, immunohistochemical staining labeled rhodopsin, retinochrome, and Gqα proteins in several chromatophore components, including pigment cell membranes, radial muscle fibers, and sheath cells. This is the first evidence that cephalopod dermal tissues, and specifically chromatophores, may possess the requisite combination of molecules required to respond to light.This research was supported by the Office of Naval Research Basic Research Challenge [grant number N00014-10-0989] via a subcontract to T.W.C. and R.T.H.2016-05-1

    Evaluation of flight foods under hypokinetic conditions, part 2, chapters 4 and 5

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    Effects of weightlessness on body temperature and heart rate determined by 56 day bed rest stud

    Observation of a baryon resonance with positive strangeness in K+ collisions with Xe nuclei

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    The status of our investigation of low-energy K+K^+Xe collisions in the Xenon bubble chamber DIANA is reported. In the charge-exchange reaction K+Xe→K0pXe′K^+Xe \to K^0 p Xe' the spectrum of K0pK^0 p effective mass shows a resonant enhancement with M=1539±2M = 1539 \pm 2 MeV/c2^2 and Γ≤9MeV/c\Gamma \le 9 MeV/c^2.Thestatisticalsignificanceoftheenhancementisnear. The statistical significance of the enhancement is near 4.4\sigma$. The mass and width of the observed resonance are consistent with expectations for the lightest member of the anti-decuplet of exotic pentaquark baryons, as predicted in the framework of the chiral soliton model.Comment: 9 pages, 4 figure

    Relation of Parkinson\u27s Disease Subtypes to Visual Activities of Daily Living

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    Visual perceptual problems are common in Parkinson\u27s disease (PD) and often affect activities of daily living (ADLs). PD patients with non-tremor symptoms at disease onset (i.e., rigidity, bradykinesia, gait disturbance or postural instability) have more diffuse neurobiological abnormalities and report worse non-motor symptoms and functional changes than patients whose initial symptom is tremor, but the relation of motor symptom subtype to perceptual deficits remains unstudied. We assessed visual ADLs with the Visual Activities Questionnaire in 25 non-demented patients with PD, 13 with tremor as the initial symptom and 12 with an initial symptom other than tremor, as well as in 23 healthy control participants (NC). As expected, the non-tremor patients, but not the tremor patients, reported more impairment in visual ADLs than the NC group, including in light/dark adaptation, acuity/spatial vision, depth perception, peripheral vision and visual processing speed. Non-tremor patients were significantly worse than tremor patients overall and on light/dark adaptation and depth perception. Environmental enhancements especially targeted to patients with the non-tremor PD subtype may help to ameliorate their functional disability

    Medical Concerns

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    Panel Chair, Greg Cox Papers Presented: Ebene: Psychedelic Snuff of the Yanomami by Kelly Partin Mycobacterium Tuberculosis: A Survey by Mary Cronin Kinematic Analysis of Universal Joint using Catia V5 by Jibin Jacob Effects of Preterm Birth by Patricia J. Campos Proposal for ETT Research using Picutre-Induced Neural Signatures by Katy N. Lee Severe Mental Illness in the Homeless by Batoul C. Zalkout Asthma Disease of the Respiratory System by Janelle Clar
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