1,683 research outputs found
First Demonstration of a Pixelated Charge Readout for Single-Phase Liquid Argon Time Projection Chambers
Liquid Argon Time Projection Chambers (LArTPCs) have been selected for the
future long-baseline Deep Underground Neutrino Experiment (DUNE). To allow
LArTPCs to operate in the high-multiplicity near detector environment of DUNE,
a new charge readout technology is required. Traditional charge readout
technologies introduce intrinsic ambiguities, combined with a slow detector
response, these ambiguities have limited the performance of LArTPCs, until now.
Here, we present a novel pixelated charge readout that enables the full 3D
tracking capabilities of LArTPCs. We characterise the signal to noise ratio of
charge readout chain, to be about 14, and demonstrate track reconstruction on
3D space points produced by the pixel readout. This pixelated charge readout
makes LArTPCs a viable option for the DUNE near detector complex.Comment: 13 pages, 9 figure
Successful Treatment of Aortic Rupture with Endovascular Stent Grafting in a Patient with Mantle Cell Lymphoma
Purpose: To present a case of spontaneous aortic rupture in the course of mantle cell lymphoma and successful management with endovascular repair. Case Report: A 69-year-old woman presented with a cervical mass. The patient was found to have stage IIIA and Mantle Cell Lymphoma International Prognostic Index (MIPI) 4. She was placed in an intermediate-risk group. The patient received an initial cycle of systemic chemotherapy consisting of rituximab, anthracycline, vincristine and methyl prednisolone. During follow-up, she developed abdominal aortic rupture secondary to intramural hematoma which was successfully managed with endovascular exclusion. Conclusion: Hemodynamic changes can be seen during the course of lymphoma subsequent to systemic chemotherapy. These changes might be related to the spontaneous rupture of the main vessels. Endovascular repair may be a more appropriate treatment option than open surgery, especially in a patient with multiple comorbidities
The influence of COMT Val158Met genotype on the character dimension cooperativeness in healthy females
Objectives: Although the Val(158)Met catechol-O-methyltransferase (COMT) gene has been linked with the temperament dimension Novelty Seeking (NS), new insights in this polymorphism might point to a major role for character features as well. Given that individual life experiences may influence Val(158) and Met(158) allele carriers differently it has been suggested that the character trait cooperativeness could be implicated.
Case report: A homogeneous group of eighty right-handed Caucasian healthy female university students were assessed with the TCI and genotyped for the COMT Val(158)Met polymorphism (rs4680). Gene determination showed that eighteen were Val(158) homozygotes, forty-four Val/Met(158) heterozygotes, and eighteen were Met(158) homozygotes. All were within the same age range and never documented to have suffered from any neuropsychiatric illness. Bonferroni corrected non-parametric analyses showed that only for the character scale cooperativeness Val(158) homozygotes displayed significant higher scores when compared to Met(158) homozygotes. No significant differences on cooperativeness scores were found between Val(158) and Val/Met(158) carriers or between Met(158) and Val/Met(158) carriers. No differences were observed for the COMT Val(158) Met polymorphism and the other temperament and character scales.
Conclusions: Our findings support the assumption that the Val(158)Met single nucleotide polymorphism (SNP) influences character traits and not only temperament. Our results add to the notion that Val(158) homozygotes are considered to be helpful and empathic and it suggest that these cooperativeness character traits are related to the dopaminergic system
Correlations of Structure and Dynamics in an Aging Colloidal Glass
We study concentrated colloidal suspensions, a model system which has a glass
transition. Samples in the glassy state show aging, in that the motion of the
colloidal particles slows as the sample ages from an initial state. We study
the relationship between the static structure and the slowing dynamics, using
confocal microscopy to follow the three-dimensional motion of the particles.
The structure is quantified by considering tetrahedra formed by quadruplets of
neighboring particles. We find that while the sample clearly slows down during
aging, the static properties as measured by tetrahedral quantities do not vary.
However, a weak correlation between tetrahedron shape and mobility is observed,
suggesting that the structure facilitates the motion responsible for the sample
aging.Comment: Submitted to Solid State Communication
The Green Economy: Functional Domains and Theoretical Directions of Enquiry
The green economy is a highly complex construct in terms of its attempts to integrate economic, environmental, and social concerns, the wide range of actors involved, its material outcomes, and the forms of governance needed to regulate processes of economic greening. As such, it poses new empirical and theoretical challenges for social science research on socioenvironmental futures. This paper has two main aims. The first is to survey the emergent features and functional domains of the green economy. The second is to consider theoretical tools that might be used to analyse the drivers and processes shaping the green economy. Focusing on literature on sociotechnical transitions, ecological modernisation, the âgreenâ cultural economy, and postpolitical governance, we argue that understanding the functional and spatial heterogeneity of the green economy necessitates a multitheoretical approach. We then explore how combining branches of research on socioenvironmental governance can lead to theoretically and ontologically richer insights into the drivers, practices, and power relations within the green economy. In so doing, we respond to calls for socioeconomic research on environmental change which is neither just empirical nor bound to one theoretical outlook to the detriment of understanding the complexity of socioenvironmental governance and humanânature relations.</jats:p
The new resilience of emerging and developing countries: systemic interlocking, currency swaps and geoeconomics
The vulnerability/resilience nexus that defined the interaction between advanced and developing economies in the post-WWII era is undergoing a fundamental transformation. Yet, most of the debate in the current literature is focusing on the structural constraints faced by the Emerging and Developing Countries (EDCs) and the lack of changes in the formal structures of global economic governance. This paper challenges this literature and its conclusions by focusing on the new conditions of systemic interlocking between advanced and emerging economies, and by analysing how large EDCs have built and are strengthening their economic resilience. We find that a significant redistribution of âpolicy spaceâ between advanced and emerging economies have taken place in the global economy. We also find that a number of seemingly technical currency swap agreements among EDCs have set in motion changes in the very structure of global trade and finance. These developments do not signify the end of EDCsâ vulnerability towards advanced economies. They signify however that the economic and geoeconomic implications of this vulnerability have changed in ways that constrain the options available to advanced economies and pose new challenges for the post-WWII economic order
Radioisotopic perfusional assessment of blood circulation changes in skin under progressive expansion: experimental model with rabbits
Prospect for Charge Current Neutrino Interactions Measurements at the CERN-PS
Tensions in several phenomenological models grew with experimental results on
neutrino/antineutrino oscillations at Short-Baseline (SBL) and with the recent,
carefully recomputed, antineutrino fluxes from nuclear reactors. At a
refurbished SBL CERN-PS facility an experiment aimed to address the open issues
has been proposed [1], based on the technology of imaging in ultra-pure
cryogenic Liquid Argon (LAr). Motivated by this scenario a detailed study of
the physics case was performed. We tackled specific physics models and we
optimized the neutrino beam through a full simulation. Experimental aspects not
fully covered by the LAr detection, i.e. the measurements of the lepton charge
on event-by-event basis and their energy over a wide range, were also
investigated. Indeed the muon leptons from Charged Current (CC) (anti-)neutrino
interactions play an important role in disentangling different phenomenological
scenarios provided their charge state is determined. Also, the study of muon
appearance/disappearance can benefit of the large statistics of CC muon events
from the primary neutrino beam. Results of our study are reported in detail in
this proposal. We aim to design, construct and install two Spectrometers at
"NEAR" and "FAR" sites of the SBL CERN-PS, compatible with the already proposed
LAr detectors. Profiting of the large mass of the two Spectrometers their
stand-alone performances have also been exploited.Comment: 70 pages, 38 figures. Proposal submitted to SPS-C, CER
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