Dissecting Visual Analytics: Comparing Frameworks for Interpreting and Modelling Observed Visual Analytics Behavior

This paper provides an empirical, comparative exploration of the role of analytic frameworks in interpreting and modelling visual analytics behavior through data gathered in observational studies. The crucial research on understanding the complex and multi-faceted interplay between visual analytics tools and their users is often done through controlled or naturalistic observations of analysts engaging in the visual analytic process, followed by the interpretation of the observation data. The researchers in Human Computer Interaction and Cognitive Sciences have long used structured analytic frameworks for such analyses, where a guiding set of principles and questions direct attention to relevant aspects of the studied behavior, eventually leading to more complete and consistent analyses. Such frameworks are rarely applied in the visualization domain however, and information about how to apply them and their benefits is scarce. With this paper, we contribute a comparative account, grounded in empirical data collected in a user study with 10 participants using Tableau to analyze domain-specific data, of the types of insights we can glean from interpreting observational data using three different frameworks: Joint Action Theory, Distributed Cognition, and Situated Cognition

Telocytes of the mammary gland stroma

Although confusions persist in what concerns the terminologies used for describing the fibroblastoid cells of the stromal compartments, the expression of antigens in such cells gradually directs their diagnosis towards a stem/progenitor phenotype. The stromal cells with long, slender and moniliform prolongations were named “telocytes” (TCs), their cell processes being termed “telopodes”. However, the mammary gland TCs were not evaluated for the CD34 expression. Thus an in vivo immunohistochemical study was designed; antibodies against CD10, CD34, CD117/c-kit and vimentin were applied on human mammary gland samples of 8 donor patients. Resident CD34-positive stromal cells positive for the TCs morphology were found building consistent stromal networks and ensheathing microvessels and excretory units. Such cells were CD10±/c-kit-/vimentin+. According to the current concepts regarding the in vivo stem/progenitor cells the CD34+ TCs of the mammary stroma could be actors in the mammary stem niche and their antigens expression could relate to different stages of differentiation

An unusual case of unilateral supernumerary extensor carpi radialis muscle

An uncommon anatomical variant of muscle that can be considered as a supernumerary extensor carpi radialis muscle was found during the dissection of the forearm region. The identified extensor carpi radialis muscle has origin on the lateral supraepicondylar ridge of the humerus, and an unusual insertion on the tubercle of the scaphoid bone. The presence of this supernumerary muscle may cause diagnostic errors in the forearm region, and can produce a debilitating pain syndrome by secondary compression of adjacent nerves, vessels or tendons due to its course along the anterior compartment of the forearm