Universality of Quantum Gravity Corrections

We show that the existence of a minimum measurable length and the related Generalized Uncertainty Principle (GUP), predicted by theories of Quantum Gravity, influence all quantum Hamiltonians. Thus, they predict quantum gravity corrections to various quantum phenomena. We compute such corrections to the Lamb Shift, the Landau levels and the tunnelling current in a Scanning Tunnelling Microscope (STM). We show that these corrections can be interpreted in two ways: (a) either that they are exceedingly small, beyond the reach of current experiments, or (b) that they predict upper bounds on the quantum gravity parameter in the GUP, compatible with experiments at the electroweak scale. Thus, more accurate measurements in the future should either be able to test these predictions, or further tighten the above bounds and predict an intermediate length scale, between the electroweak and the Planck scale.Comment: v1: 4 pages, LaTeX; v2: typos corrected, references updated, version to match published version in Physical Review Letter

Cell-type phylogenetics and the origin of endometrial stromal cells

SummaryA challenge of genome annotation is the identification of genes performing specific biological functions. Here, we propose a phylogenetic approach that utilizes RNA-seq data to infer the historical relationships among cell types and to trace the pattern of gene-expression changes on the tree. The hypothesis is that gene-expression changes coincidental with the origin of a cell type will be important for the function of the derived cell type. We apply this approach to the endometrial stromal cells (ESCs), which are critical for the initiation and maintenance of pregnancy. Our approach identified well-known regulators of ESCs, PGR and FOXO1, as well as genes not yet implicated in female fertility, including GATA2 and TFAP2C. Knockdown analysis confirmed that they are essential for ESC differentiation. We conclude that phylogenetic analysis of cell transcriptomes is a powerful tool for discovery of genes performing cell-type-specific functions

A proposal for testing Quantum Gravity in the lab

Attempts to formulate a quantum theory of gravitation are collectively known as {\it quantum gravity}. Various approaches to quantum gravity such as string theory and loop quantum gravity, as well as black hole physics and doubly special relativity theories predict a minimum measurable length, or a maximum observable momentum, and related modifications of the Heisenberg Uncertainty Principle to a so-called generalized uncertainty principle (GUP). We have proposed a GUP consistent with string theory, black hole physics and doubly special relativity theories and have showed that this modifies all quantum mechanical Hamiltonians. When applied to an elementary particle, it suggests that the space that confines it must be quantized, and in fact that all measurable lengths are quantized in units of a fundamental length (which can be the Planck length). On the one hand, this may signal the breakdown of the spacetime continuum picture near that scale, and on the other hand, it can predict an upper bound on the quantum gravity parameter in the GUP, from current observations. Furthermore, such fundamental discreteness of space may have observable consequences at length scales much larger than the Planck scale. Because this influences all the quantum Hamiltonians in an universal way, it predicts quantum gravity corrections to various quantum phenomena. Therefore, in the present work we compute these corrections to the Lamb shift, simple harmonic oscillator, Landau levels, and the tunneling current in a scanning tunneling microscope.Comment: v1: 10 pages, REVTeX 4, no figures; v2: minor typos corrected and a reference added. arXiv admin note: has substantial overlap with arXiv:0906.5396 , published in a different journa

Clustering of the Diffuse Infrared Light from the COBE DIRBE maps. III. Power spectrum analysis and excess isotropic component of fluctuations

The cosmic infrared background (CIB) radiation is the cosmic repository for energy release throughout the history of the universe. Using the all-sky data from the COBE DIRBE instrument at wavelengths 1.25 - 100 mic we attempt to measure the CIB fluctuations. In the near-IR, foreground emission is dominated by small scale structure due to stars in the Galaxy. There we find a strong correlation between the amplitude of the fluctuations and Galactic latitude after removing bright foreground stars. Using data outside the Galactic plane ($|b| > 20\deg$) and away from the center ($90\deg< l <270\deg$) we extrapolate the amplitude of the fluctuations to cosec$|b|=0$. We find a positive intercept of $\delta F_{\rm rms} = 15.5^{+3.7}_{-7.0},5.9^{+1.6}_{-3.7}, 2.4^{+0.5}_{-0.9}, 2.0^{+0.25}_{-0.5}$ nW/m2/sr at 1.25, 2.2,3.5 and 4.9 mic respectively, where the errors are the range of 92% confidence limits. For color subtracted maps between band 1 and 2 we find the isotropic part of the fluctuations at $7.6^{+1.2}_{-2.4}$ nW/m2/sr. Based on detailed numerical and analytic models, this residual is not likely to originate from the Galaxy, our clipping algorithm, or instrumental noise. We demonstrate that the residuals from the fit used in the extrapolation are distributed isotropically and suggest that this extra variance may result from structure in the CIB. For 2\deg< \theta < 15^\deg, a power-spectrum analysis yields firm upper limits of (\theta/5^\deg) \times\delta F_{\rm rms} (\theta) < 6, 2.5, 0.8, 0.5 nW/m2/sr at 1.25, 2.2, 3.5 and 4.9 mic respectively. From 10-100 mic, the upper limits <1 nW/m2/sr.Comment: Ap.J., in press. 69 pages including 24 fig

Gravitational anomalies: a recipe for Hawking radiation

We explore the method of Robinson and Wilczek for deriving the Hawking temperature of a black hole. In this method, the Hawking radiation restores general covariance in an effective theory of near-horizon physics which otherwise exhibits a gravitational anomaly at the quantum level. The method has been shown to work for broad classes of black holes in arbitrary spacetime dimensions. These include static black holes, accreting or evaporating black holes, charged black holes, rotating black holes, and even black rings. In the case of charged and rotating black holes, the expected super-radiant current is also reproduced.Comment: 7 pages; This essay received an "Honorable Mention" in the 2007 Essay Competition of the Gravity Research Foundation; (v2) Short comments and references added; (v3) Minor revisions and updated references to agree with published versio

A Pseudorandom Binary Noise Ultrasonic System

The random noise ultrasonic system represents the state-of-the-art in terms of sensitivity and resolution for ultrasonic NDE systems. The principle impediment to its use in the field is the lack of real-time inspection capability. If a pair of pseudorandom binary noise sources are substituted for the white noise source in the random noise system, a real-time capability is achieved. An instrument using such sources will be demonstrated and its capabilities will be discussed