577 research outputs found
Sensory Motor Remapping of Space in Human-Machine Interfaces
Studies of adaptation to patterns of deterministic forces have revealed the ability of the motor control system to form and use predictive representations of the environment. These studies have also pointed out that adaptation to novel dynamics is aimed at preserving the trajectories of a controlled endpoint, either the hand of a subject or a transported object. We review some of these experiments and present more recent studies aimed at understanding how the motor system forms representations of the physical space in which actions take place. An extensive line of investigations in visual information processing has dealt with the issue of how the Euclidean properties of space are recovered from visual signals that do not appear to possess these properties. The same question is addressed here in the context of motor behavior and motor learning by observing how people remap hand gestures and body motions that control the state of an external device. We present some theoretical considerations and experimental evidence about the ability of the nervous system to create novel patterns of coordination that are consistent with the representation of extrapersonal space. We also discuss the perspective of endowing humanâmachine interfaces with learning algorithms that, combined with human learning, may facilitate the control of powered wheelchairs and other assistive devices
Increased risk of malignant mesothelioma of the pleura after residential or domestic exposure to asbestos: a case-control study in Casale Monferrato, Italy.
The association of malignant mesothelioma (MM) and nonoccupational asbestos exposure is currently debated. Our study investigates environmental and domestic asbestos exposure in the city where the largest Italian asbestos cement (AC) factory was located. This population-based case-control study included pleural MM (histologically diagnosed) incidents in the area in 1987-1993, matched by age and sex to two controls (four if younger than 60). Diagnoses were confirmed by a panel of five pathologists. We interviewed 102 cases and 273 controls in 1993-1995, out of 116 and 330 eligible subjects. Information was checked and completed on the basis of factory and Town Office files. We adjusted analyses for occupational exposure in the AC industry. In the town there were no other relevant industrial sources of asbestos exposure. Twenty-three cases and 20 controls lived with an AC worker [odds ratio (OR) = 4.5; 95% confidence interval (CI), 1.8-11.1)]. The risk was higher for the offspring of AC workers (OR = 7.4; 95% CI, 1.9-28.1). Subjects attending grammar school in Casale also showed an increased risk (OR = 3.3; 95% CI, 1.4-7.7). Living in Casale was associated with a very high risk (after selecting out AC workers: OR = 20.6; 95% CI, 6.2-68.6), with spatial trend with increasing distance from the AC factory. The present work confirms the association of environmental asbestos exposure and pleural MM, controlling for other sources of asbestos exposure, and suggests that environmental exposure caused a greater risk than domestic exposure
The dynamics of motor learning through the formation of internal models
A medical student learning to perform a laparoscopic procedure or a recently paralyzed user of a powered wheelchair must learn to operate machinery via interfaces that translate their actions into commands for an external device. Since the user\u2019s actions are selected from a number of alternatives that would result in the same effect in the control space of the external device, learning to use such interfaces involves dealing with redundancy. Subjects need to learn an externally chosen many-to-one map that transforms their actions into device commands. Mathematically, we describe this type of learning as a deterministic dynamical process, whose state is the evolving forward and inverse internal models of the interface. The forward model predicts the outcomes of actions, while the inverse model generates actions designed to attain desired outcomes. Both the mathematical analysis of the proposed model of learning dynamics and the learning performance observed in a group of subjects demonstrate a first-order exponential convergence of the learning process toward a particular state that depends only on the initial state of the inverse and forward models and on the sequence of targets supplied to the users. Noise is not only present but necessary for the convergence of learning through the minimization of the difference between actual and predicted outcomes
Tactile Proprioceptive Input in Robotic Rehabilitation after Stroke
Stroke can lead to loss or impairment of somatosensory sensation (i.e. proprioception), that reduces functional control of limb movements. Here we examine the possibility of providing artificial feedback to make up for lost sensory information following stroke. However, it is not clear whether this kind of sensory substitution is even possible due to stroke-related loss of central processing pathways that subserve somatosensation. In this paper we address this issue in a small cohort of stroke survivors using a tracking task that emulates many activities of daily living. Artificial proprioceptive information was provided to the subjects in the form of vibrotactile cues. The goal was to assist participants in guiding their arm towards a moving target on the screen. Our experiment indicates reliable tracking accuracy under the effect of vibrotactile proprioceptive feedback, even in subjects with impaired natural proprioception. This result is promising and can create new directions in rehabilitation robotics with augmented somatosensory feedback
Conventional and algorithmic music listening before radiotherapy treatment: A randomized controlled pilot study
Music listening is a widespread approach in the field of music therapy. In this study, the effects of music listening on anxiety and stress in patients undergoing radiotherapy are investigated. Sixty patients with breast cancer who were candidates for postoperative curative radiotherapy were recruited and randomly assigned to three groups: Melomics-Health (MH) group (music listening algorithmically created, n = 20); individualized music listening (IML) group (playlist of preferred music, n = 20); no music group (n = 20). Music listening was administered for 15 min immediately before simulation and during the first five radiotherapy sessions. The State-Trait Anxiety Inventory (STAI) and the Psychological Distress Inventory (PDI) were administered before/after treatment. Cochranâs Q test and McNemar test for paired proportions were performed to evaluate if the proportion of subjects having an outcome score below the critical value by treatment and over time was different, and if there was a change in that proportion. The MH group improved in STAI and PDI. The IML group worsened in STAI at T1 and improved STAI-Trait at T2. The IML group worsened in PDI at T2. The No music group generally improved in STAI and PDI. Clinical and music listening-related implications are discussed defining possible research perspectives in this field
Caratterizzazione dellâambiente marino dei Campi Flegrei. Risultati preliminari della campagna oceanografica RICAMAR 2013
The caldera of the Phlegraean Fields (also known as Campi Flegrei) is one of the most dangerous and populated volcanic area in the world, covering an area that comprises the western part of Naples and the Gulf of Pozzuoli. The main peculiarity of current volcanic activity is the gradual and periodic lift (positive or negative) of part of the Earth\u27s surface (bradyseism) combined, only during the positive phase, with a strong sismicity and surficial hydrotermal activity. Deformative models, calibrated using land-based measurements, highlighted the Gulf of Pozzuoli as the area with the largest deformation. Although the network of monitoring sensors on land is well developed and structured, there is a lack of sensing systems for the marine deformation. The activities of RIlievi per la Caratterizzazione dellâAmbiente MARino nel Golfo di Pozzuoli 2013 (RICAMAR2013) project - sinergically conducted by the Italian Navy\u27s Survey Vessel Ammiraglio Magnaghi , the Italian Hydrographic Office (IIM) and the Istituto Nazionale di Geofisica e Vulcanologia (INGV)- were targeted to fulfill this gap. In fact, the creation of marine observatories about the caldera\u27s phenomena will be based on the data collected during these bathymetric, magnetometric, stratigrafic and hydrologic surveys
Upper Body-Based Power Wheelchair Control Interface for Individuals with Tetraplegia
Many power wheelchair control interfaces are not sufficient for individuals with severely limited upper limb mobility. The majority of controllers that do not rely on coordinated arm and hand movements provide users a limited vocabulary of commands and often do not take advantage of the user's residual motion. We developed a body-machine interface (BMI) that leverages the flexibility and customizability of redundant control by using high dimensional changes in shoulder kinematics to generate proportional control commands for a power wheelchair. In this study, three individuals with cervical spinal cord injuries were able to control a power wheelchair safely and accurately using only small shoulder movements. With the BMI, participants were able to achieve their desired trajectories and, after five sessions driving, were able to achieve smoothness that was similar to the smoothness with their current joystick. All participants were twice as slow using the BMI however improved with practice. Importantly, users were able to generalize training controlling a computer to driving a power wheelchair, and employed similar strategies when controlling both devices. Overall, this work suggests that the BMI can be an effective wheelchair control interface for individuals with high-level spinal cord injuries who have limited arm and hand control
Multicentric study on malignant pleural mesothelioma and non-occupational exposure to asbestos
Insufficient evidence exists on the risk of pleural mesothelioma from non-occupational exposure to asbestos. A population-based caseâcontrol study was carried out in six areas from Italy, Spain and Switzerland. Information was collected for 215 new histologically confirmed cases and 448 controls. A panel of industrial hygienists assessed asbestos exposure separately for occupational, domestic and environmental sources. Classification of domestic and environmental exposure was based on a complete residential history, presence and use of asbestos at home, asbestos industrial activities in the surrounding area, and their distance from the dwelling. In 53 cases and 232 controls without evidence of occupational exposure to asbestos, moderate or high probability of domestic exposure was associated with an increased risk adjusted by age and sex: odds ratio (OR) 4.81, 95% confidence interval (CI) 1.8â13.1. This corresponds to three situations: cleaning asbestos-contaminated clothes, handling asbestos material and presence of asbestos material susceptible to damage. The estimated OR for high probability of environmental exposure (living within 2000 m of asbestos mines, asbestos cement plants, asbestos textiles, shipyards, or brakes factories) was 11.5 (95% CI 3.5â38.2). Living between 2000 and 5000 m from asbestos industries or within 500 m of industries using asbestos could also be associated with an increased risk. A doseâresponse pattern appeared with intensity of both sources of exposure. It is suggested that low-dose exposure to asbestos at home or in the general environment carries a measurable risk of malignant pleural mesothelioma. © 2000 Cancer Research Campaig
Performance evaluation of an axially viewed horizontal inductively coupled plasma for optical emission spectrometry
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