Physical and Tribological Characteristics of Ion-Implanted Diamond Films

Unidirectional sliding friction experiments were conducted with a natural, polished diamond pin in contact with both as-deposited and carbon-ion-implanted diamond films in ultrahigh vacuum. Diamond films were deposited on silicon, silicon carbide, and silicon nitride by microwave-plasma-assisted chemical vapor deposition. The as-deposited diamond films were impacted with carbon ions at an accelerating energy of 60 keV and a current density of 50 micron A/cm(exp 2) for approximately 6 min, resulting in a dose of 1.2 x 10(exp 17) carbon ions/cm(exp 2). The results indicate that the carbon ion implantation produced a thin surface layer of amorphous, nondiamond carbon. The nondiamond carbon greatly decreased both friction and wear of the diamond films. The coefficients of friction for the carbon-ion-implanted, fine-grain diamond films were less than 0.1, factors of 20 to 30 lower than those for the as-deposited, fine-grain diamond films. The coefficients of friction for the carbon-ion-implanted, coarse-grain diamond films were approximately 0.35, a factor of five lower than those for the as-deposited, coarse-grain diamond films. The wear rates for the carbon-ion-implanted, diamond films were on the order of 10(exp -6) mm(exp 3)/Nm, factors of 30 to 80 lower than that for the as-deposited diamond films, regardless of grain size. The friction of the carbon-ion-implanted diamond films was greatly reduced because the amorphous, nondiamond carbon, which had a low shear strength, was restricted to the surface layers (less than 0.1 micron thick) and because the underlying diamond materials retained their high hardness. In conclusion, the carbon-ion-implanted, fine-grain diamond films can be used effectively as wear resistant, self-lubricating coatings for ceramics, such as silicon nitride and silicon carbide, in ultrahigh vacuum

Analysis of arterial intimal hyperplasia: review and hypothesis

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background: Despite a prodigious investment of funds, we cannot treat or prevent arteriosclerosis and restenosis, particularly its major pathology, arterial intimal hyperplasia. A cornerstone question lies behind all approaches to the disease: what causes the pathology? Hypothesis: I argue that the question itself is misplaced because it implies that intimal hyperplasia is a novel pathological phenomenon caused by new mechanisms. A simple inquiry into arterial morphology shows the opposite is true. The normal multi-layer cellular organization of the tunica intima is identical to that of diseased hyperplasia; it is the standard arterial system design in all placentals at least as large as rabbits, including humans. Formed initially as one-layer endothelium lining, this phenotype can either be maintained or differentiate into a normal multi-layer cellular lining, so striking in its resemblance to diseased hyperplasia that we have to name it "benign intimal hyperplasia". However, normal or "benign " intimal hyperplasia, although microscopically identical to pathology, is a controllable phenotype that rarely compromises blood supply. It is remarkable that each human heart has coronary arteries in which a single-layer endothelium differentiates earl

Inter-hospital transfer for mechanical thrombectomy within the supraregional stroke network NEVAS

BACKGROUND Telemedicine stroke networks are mandatory to provide inter-hospital transfer for mechanical thrombectomy (MT). However, studies on patient selection in daily practice are sparse. METHODS Here, we analyzed consecutive patients from 01/2014 to 12/2018 within the supraregional stroke network \textquotedblNeurovascular Network of Southwest Bavaria\textquotedbl (NEVAS) in terms of diagnoses after consultation, inter-hospital transfer and predictors for performing MT. Degree of disability was rated by the modified Rankin Scale (mRS), good outcome was defined as mRS ≤ 2. Successful reperfusion was assumed when the modified thrombolysis in cerebral infarction (mTICI) was 2b-3. RESULTS Of 5722 telemedicine consultations, in 14.1% inter-hospital transfer was performed, mostly because of large vessel occlusion (LVO) stroke. A total of n = 350 patients with LVO were shipped via NEVAS to our center for MT. While n = 52 recanalized spontaneously, MT-treatment was performed in n = 178 patients. MT-treated patients had more severe strokes according to the median National institute of health stroke scale (NIHSS) (16 vs. 13, p < 0.001), were more often treated with intravenous thrombolysis (64.5% vs. 51.7%, p = 0.026) and arrived significantly earlier in our center (184.5 versus 228.0~min, p < 0.001). Good outcome (27.5% vs. 30.8%, p = 0.35) and mortality (32.6% versus 23.5%, p = 0.79) were comparable in MT-treated versus no-MT-treated patients. In patients with middle cerebral artery occlusion in the M1 segment or carotid artery occlusion good outcome was twice as often in the MT-group (21.8% vs. 12.8%, p = 0.184). Independent predictors for performing MT were higher NIHSS (OR 1.096), higher ASPECTS (OR 1.28), and earlier time window (OR 0.99). CONCLUSION Within a telemedicine network stroke care can successfully be organized as only a minority of patients has to be transferred. Our data provide clinical evidence that all MT-eligible patients should be shipped with the fastest transportation modality as possible

Solid Dielectric Transmission Lines for Pulsed Power

This paper documents recent work developing solid dielectric transmission lines for sub-microsecond, 100 kV class compact pulsed power systems. Polymer-ceramic nanocomposite materials have demonstrated sub-microsecond discharge capability in parallel plate capacitors and transmission lines [1, 2]. With a dielectric constant of approximately 50, the propagation velocity is 2.5 cm/ns, necessitating lines of several meters length to achieve \u3e 100 ns pulse lengths. By folding the line in a fashion analogous to ceramic multilayer capacitors, the physical length of the line can be significantly shorter than the electrical length. We present the results of an experimental effort to develop a folded transmission line using a polymer-ceramic nanocomposite dielectric. The pulse length was somewhat shorter than expected based on a simple calculation using the geometry and the dielectric constant. Fully 3-D electromagnetic calculations were used to examine the role of the edges in curtailing the pulse length. Dielectric breakdown in this device occurred below the electric field threshold demonstrated in the prior work [1]. Improvements in the large scale fabrication of TiO2 beginning with nanoscale grains have opened the possibility for producing single layer high voltage devices. Given a dielectric constant approaching 140, transmission lines using nano-TiO2 can be considerably shorter than with other materials. Relatively thick, flat sheets of TiO2 have been fabricated for testing up to 50 kV. Several transmission lines, employing a serpentine electrode geometry, have been manufactured and tested. Testing up to several 10\u27s of kV has confirmed the operation of the lines according to the design. As expected, the triple point between the TiO2, electrode, and insulating medium has proven difficult to manage for high voltage operation. Several techniques to mitigate the effects of the triple point, including resistive grading at the edges of the electrodes, are discussed. Fully 3-D electromagnetic modeling is used to examine the effects of electrode geometry and composition on the performance of the lines