A Distributed Algorithm for Demand Response with Mixed-Integer Variables

This letter presents a fast distributed algorithm for aggregating a large number of households with mixed-integer variables and intricate couplings between devices. The proposed fast distributed gradient algorithm is applied to the double smoothed dual function of the adopted DR model. The results also show that, with minimal parameter adjustments, the convergence of the dual objective exhibits the same behavior irrespective of the system size.Comment: 2 pages, 1 figure, to be published in IEEE Transactions on Smart Grid Letter

Exploration of Reaction Pathways and Chemical Transformation Networks

For the investigation of chemical reaction networks, the identification of all relevant intermediates and elementary reactions is mandatory. Many algorithmic approaches exist that perform explorations efficiently and automatedly. These approaches differ in their application range, the level of completeness of the exploration, as well as the amount of heuristics and human intervention required. Here, we describe and compare the different approaches based on these criteria. Future directions leveraging the strengths of chemical heuristics, human interaction, and physical rigor are discussed.Comment: 48 pages, 4 figure

Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2

The bacterial bioluminescence system enables the generation of light by living cells without the requirement of an external luciferin. Due to the relatively low light emission, many applications of bioluminescence imaging would benefit from an increase in brightness of this system. In this report, a new approach of mutagenesis and screening of the involved proteins is described that is based on the identification of mutants with improved properties under rate-limiting reaction conditions. Multiple rounds of screening in Escherichia coli resulted in the operon ilux2 that contains 26 new mutations in the fatty acid reductase complex which provides the aldehyde substrate for the bioluminescence reaction. Chromosomal integration of ilux2 yielded an autonomously bioluminescent E. coli strain with sixfold increased brightness compared to the previously described ilux operon. The ilux2 strain produces sufficient signal for the robust detection of individual cells and enables highly sensitive long-term imaging of bacterial propagation without a selection marker

Dynamic Kerr effect responses in the Terahertz-range

Dynamic Kerr effect measurements provide a simple realization of a nonlinear experiment. We propose a field-off experiment where an electric field of one or several sinusoidal cycles is applied to a sample in thermal equilibrium. Afterwards, the evolution of the polarizability is measured. If such an experiment is performed in the Terahertz-range it might provide valuable information about the low-frequency dynamics in disordered systems. We treat these dynamics in terms of a Brownian oscillator model and calculate the Kerr effect response. It is shown that frequency-selective behaviour can be expected. In the interesting case of underdamped vibrational motion we find that the frequency-dependence of the phonon-damping can be determined from the experiment. Also the behaviour of overdamped relaxational modes is discussed. For typical glassy materials we estimate the magnitude of all relevant quantities, which we believe to be helpful in experimental realizations.Comment: 26 pages incl. 5 figure