361 research outputs found

    The Motivation Beliefs Inventory: Measuring Motivation Beliefs Using Four Motivation Theories

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    Among organizational consultants, human resources practitioners, and organizational leaders, there has been a resurgence of interest in the subject of employee motivation, in part due to the best-selling book, Drive (Pink, 2009). In this book, the author challenged readers to question their beliefs about what motivates employees; this challenge was based on research that questions the validity of widely used management approaches to employee motivation, particularly those based on reinforcement theory. Answering this challenge was difficult, however, given the lack of instruments designed to measure motivation beliefs at all, much less beliefs from a range of prevalent theories. Using principal components and parallel analyses, the 20-item Motivation Beliefs Inventory (MBI) was created to measure motivation beliefs along four theoretical lines: reinforcement theory; expectancy-valence theory; achievement motivation theory; and self-determination theory. The instrument was validated in two tests involving large samples of businesspeople. Validity and reliability analyses revealed the instrument demonstrates acceptable psychometric properties. Four subscales, each representing a single theory, were confirmed and demonstrated alpha coefficients as follows: reinforcement theory, .77; expectancy-valence theory, .71; achievement motivation theory, .82; self-determination theory, .77. The entire Motivation Beliefs Inventory produced a strong alpha coefficient of .77. In addition to validating the instrument, this study generated several significant findings. The first of these revealed that there were statistically significant differences in the distribution of beliefs about what motivates employees; specifically, self-determination beliefs were most strongly held, followed by expectancy-valence theory and achievement motivation theory beliefs. Despite their dominant role in organizational systems, respondents agreed with tenets of reinforcement theory at the lowest level. Furthermore, based on effect size analysis, males were more likely than females to agree with reinforcement theory and achievement motivation theory, while non-managers were more likely than managers to agree with self-determination theory. As expected, the creation of a new instrument like the MBI opens a world of possibilities for both practitioners and scholars. While workplace practitioners now have the ability to actually measure an individual\u27s beliefs about motivation, researchers can use the instrument to test for differences in these beliefs among individuals in different occupations, companies, industries, and countries

    Ethyl glucuronide as a long-term alcohol biomarker in fingernail and hair

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    Aims: This work aimed to assess the performance of hair and fingernail ethyl glucuronide (EtG) measurement for use as a biomarker of alcohol consumption in persons with known drinking history across a range of drinking behaviours. Methods: EtG concentrations were assessed from the hair and fingernails of 50 study participants. Alcohol consumption of the previous 90 days was assessed by participant interview using the alcohol time-line follow-back (TLFB) method. EtG concentration was determined using LC/MS-MS using a method which was validated and accredited to ISO/IEC 17025 standards. Results: There was significant correlation between alcohol consumption and EtG concentrations found in hair and fingernail samples across the study group (n=50). From participants testing positive for EtG (male n=14, female n=13) no significant difference was found between male and female EtG levels in either hair or fingernails. Across all participants there was no significant difference in hair or fingernail EtG concentration between male (n=23) and females (n=27). Conclusions: Our results support the use of EtG to indicate alcohol consumption over the previous 90 days, or approximately 3 months as is the normal practice in hair analysis. The results confirm that fingernails can be a useful alternative matrix where hair samples are not available

    Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1G93A motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice

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    Background: In humans, mutations in the enzyme glycyl-tRNA synthetase (GARS) cause motor and sensory axon loss in the peripheral nervous system, and clinical phenotypes ranging from Charcot-Marie-Tooth neuropathy to a severe infantile form of spinal muscular atrophy. GARS is ubiquitously expressed and may have functions in addition to its canonical role in protein synthesis through catalyzing the addition of glycine to cognate tRNAs. Methodology/Principal findings: We have recently described a new mouse model with a point mutation in the Gars gene resulting in a cysteine to arginine change at residue 201. Heterozygous Gars^{C201R/+} mice have locomotor and sensory deficits. In an investigation of genetic mutations that lead to death of motor and sensory neurons, we have crossed the Gars^{C201R/+} mice to two other mutants: the TgSOD1^{G93A} model of human amyotrophic lateral sclerosis and the Legs at odd angles mouse (Dync1h1^{Loa}) which has a defect in the heavy chain of the dynein complex. We found the Dync1h1^{Loa/+}; Gars^{C201R/+} double heterozygous mice are more impaired than either parent, and this is may be an additive effect of both mutations. Surprisingly, the Gars^{C201R} mutation significantly delayed disease onset in the SOD1^{G93A}; Gars^{C201R/+} double heterozygous mutant mice and increased lifespan by 29% on the genetic background investigated. Conclusions/Significance: These findings raise intriguing possibilities for the study of pathogenetic mechanisms in all three mouse mutant strains

    Many-body spin related phenomena in ultra-low-disorder quantum wires

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    Zero length quantum wires (or point contacts) exhibit unexplained conductance structure close to 0.7 X 2e^2/h in the absence of an applied magnetic field. We have studied the density- and temperature-dependent conductance of ultra-low-disorder GaAs/AlGaAs quantum wires with nominal lengths l=0 and 2 mu m, fabricated from structures free of the disorder associated with modulation doping. In a direct comparison we observe structure near 0.7 X 2e^2/h for l=0 whereas the l=2 mu m wires show structure evolving with increasing electron density to 0.5 X 2e^2/h in zero magnetic field, the value expected for an ideal spin-split sub-band. Our results suggest the dominant mechanism through which electrons interact can be strongly affected by the length of the 1D region.Comment: 5 Pages, 4 figure

    The pathophysiology of malarial anaemia: where have all the red cells gone?

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    Malarial anaemia is an enormous public health problem in endemic areas and occurs predominantly in children in the first 3 years of life. Anaemia is due to both a great increase in clearance of uninfected cells and a failure of an adequate bone marrow response. Odhiambo, Stoute and colleagues show how the age distribution of malarial anaemia and the haemolysis of red blood cells may be linked by an age-dependent increase in the capacity of red blood cells to inactivate complement components absorbed or deposited directly on to the surface of the red blood cell. In this commentary, we discuss what has been established about the role of complement deposition on the surface of red blood cells in the pathology of malarial anaemia, how genetic polymorphisms of the complement control proteins influence the outcome of malaria infection and how the findings of Odhiambo, Stoute and colleagues and others shed light on the puzzling age distribution of different syndromes of severe malaria

    Science lives: School choices and ‘natural tendencies’

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    An analysis of 12 semi-structured interviews with university-based scientists and non-scientists illustrates their life journeys towards, or away from, science and the strengths and impact of life occurrences leading them to choose science or non-science professions. We have adopted narrative approaches and used Mezirow's transformative learning theory framework. The areas of discussion from the result have stressed on three main categories that include ‘smooth transition’, ‘incremental wavering transition' and ‘transformative transition’. The article concludes by discussing the key influences that shaped initial attitudes and direction in these people through natural inclination, environmental inspirations and perceptions of science

    Investigating pupils’ interactions around digital texts: a spatial perspective on the ‘classroom-ness’ of digital literacy practices in schools

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    This paper complements debates around use of new technologies and literacy in education by proposing a focus on “classroom-ness.” It highlights the significance of incidental, everyday and ephemeral practices associated with classroom technology-use. Using examples from a study of primary pupils’ interactions around digital texts, it argues that we must acknowledge the distinctiveness of technology-use in classroom contexts but also see the spaces associated with those contexts as continually constructed, relational and heterogeneous. This helps us look beyond binary distinctions – between in/out of school and global/local practices, on/off-screen and on/offline activity, material/virtual contexts and official/unofficial discourses – to recognise the complex and nuanced ways that children make meaning around new technologies. It is proposed that this theoretical lens – in recognising the complexity of classroom-ness – can help us better understand the barriers and opportunities associated with effective integration of new technologies in educational contexts
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