Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated: a prospective study using patient-reported outcome measures

We aimed to determine short-term patient-reported outcomes in men having general anesthetic transperineal (TP) prostate biopsies. A prospective cohort study was performed in men having a diagnostic TP biopsy. This was done using a validated and adapted questionnaire immediately post-biopsy and at follow-up of between 7 and 14 days across three tertiary referral hospitals with a response rate of 51.6%. Immediately after biopsy 43/201 (21.4%) of men felt light-headed, syncopal, or suffered syncope. Fifty-three percent of men felt discomfort after biopsy (with 95% scoring <5 in a 0-10 scale). Twelve out of 196 men (6.1%) felt pain immediately after the procedure. Despite a high incidence of symptoms (e.g., up to 75% had some hematuria, 47% suffered some pain), it was not a moderate or serious problem for most, apart from hemoejaculate which 31 men suffered. Eleven men needed catheterization (5.5%). There were no inpatient admissions due to complications (hematuria, sepsis). On repeat questioning at a later time point, only 25/199 (12.6%) of men said repeat biopsy would be a significant problem despite a significant and marked reduction in erectile function after the procedure. From this study, we conclude that TP biopsy is well tolerated with similar side effect profiles and attitudes of men to repeat biopsy to men having TRUS biopsies. These data allow informed counseling of men prior to TP biopsy and a benchmark for tolerability with local anesthetic TP biopsies being developed for clinical use.Boris Hadaschik received funding from the German Research Foundation and the European Foundation for Urology. Karan Wadhwa is sponsored by a Medical Research Council Research Training Fellowship. No other funding was received for this work

DEVELOPMENT OF DIGITAL HUMAN BODY TRACKIER ALARM SYSTEM USING GPS AND TRANSCEIVER FOR CATASTROPHIC EVENTS' RESCUE OPERATION

Catastrophic events especially natural disasters are one of the most devastating events countries around the world normally experience nowadays. One major problem is that disasters leave some countries with a massive destruction and most of the time it kills and destroys the life of the people. After such said event, the lives of the people would become unpredictable because some of them have might survive would die instantly. This is where the researchers thought of conducting a study that would be useful every time these catastrophic events will occur. The study focused on the development of digital human body tracker alarm system (DHBT AS). The DHBT AS is a device to be monitored by the rescuers who will help the survivors during tragedy. The device is incorporated with GPS and transceiver to locate the survivors. The location in the form of latitude and longitude coordinates will be displayed on the LCD monitor of the DHBT AS. Using the coordinates at wiki map, it would be easier for the rescuers to locate the survivors with respect to the location of the DHBT AS. The device is also incorporated with a buzzer to alarm the rescuers the respective distance between the device and the survivor. The more abrupt the sound of the buzz is, the nearer is the rescuer to the survivor. The DHBT AS has its partner which is the rescue and operation device (ROP) which is to be worn by the victim; According to the tracked number of ROPs, the rescuers will be able to track the location and know the number of persons who still have a chance to live or survive within the 100m radius of the DHBT AS location. Moreover, the Rap device has its button that is to be pushed by the victim to inform the rescuers that they badly needed assistance or help as soon as possible. Pushing the button will allow the rescuers prioritize the need of the respective Rap wearer. The overall system trials gave an average delay of 2.4 seconds waiting time before the GPS satellite locator can give exact location

Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated: a prospective study using patient-reported outcome measures

We aimed to determine short-term patient-reported outcomes in men having general anesthetic transperineal (TP) prostate biopsies. A prospective cohort study was performed in men having a diagnostic TP biopsy. This was done using a validated and adapted questionnaire immediately post-biopsy and at follow-up of between 7 and 14 days across three tertiary referral hospitals with a response rate of 51.6%. Immediately after biopsy 43/201 (21.4%) of men felt light-headed, syncopal, or suffered syncope. Fifty-three percent of men felt discomfort after biopsy (with 95% scoring <5 in a 0-10 scale). Twelve out of 196 men (6.1%) felt pain immediately after the procedure. Despite a high incidence of symptoms (e.g., up to 75% had some hematuria, 47% suffered some pain), it was not a moderate or serious problem for most, apart from hemoejaculate which 31 men suffered. Eleven men needed catheterization (5.5%). There were no inpatient admissions due to complications (hematuria, sepsis). On repeat questioning at a later time point, only 25/199 (12.6%) of men said repeat biopsy would be a significant problem despite a significant and marked reduction in erectile function after the procedure. From this study, we conclude that TP biopsy is well tolerated with similar side effect profiles and attitudes of men to repeat biopsy to men having TRUS biopsies. These data allow informed counseling of men prior to TP biopsy and a benchmark for tolerability with local anesthetic TP biopsies being developed for clinical use.Boris Hadaschik received funding from the German Research Foundation and the European Foundation for Urology. Karan Wadhwa is sponsored by a Medical Research Council Research Training Fellowship. No other funding was received for this work