Improved Healing of Pressure Ulcers Using Dermapulse, A New Electrical Stimulation Device

A double-blind, clinical study of pulsed electrical stimulation using the Dermapulse® device was carried out on 40 pressure ulcers, randomized to receive either active (stim) or sham treatment. Electrodes were placed over saline-moistened gauze on the ulcers. An electrical current of 35mA was delivered to the wound tissues at a frequency of 128 pulses per second. Polarity was negative until the wound debrided, then alternated from .positive to negative every three days. Ulcers were treated for 30 minutes twice daily for four weeks, after which sham patients could cross over to active treatment, and stim patients could continue active treatment. Ulcer healing was determined by measuring the length and width of the ulcer and calculating the L x W product. The same clinicians measured the ulcers each week, were kept blinded to treatment group, and were not the same persons who applied the treatment. Nine centers treated 40 ulcers (19 sham and 21 stim). Analysis of the characteristics of the patients, the ulcers, and concomitant wound care by both univariate and multivariate analyses showed comparability of the groups. After four weeks, the stim ulcers healed more than twice as much as the sham ulcers (49.8% vs. 23.4%; (p = 0.042). The stim ulcers healed 12.5% per week compared to 5.8% for the sham group. In the 15 crossover patients, four weeks of active stimulation caused nearly four times as much healing as their four weeks of sham treatment (47.9% vs. 13.4%; p = 0.012). By the last week of-active stimulation they had healed an average of 64%, and complete healing occurred in 40% of these ulcers after an average of nine weeks. Seventeen of the active treatment ulcers had extended therapy, and by their last week of treatment had healed an average of 75%. Forty-one percent of these ulcers healed completely after an average of 11.8 weeks. There were no significant safety problems identified

Justice Reinvestment as Social Justice

This chapter draws on the work of the Australian Justice Reinvestment Project (AJRP) (Brown et al., 2015). The AJRP examined the development of justice reinvestment particularly in the context of it’s alignment with broad social justice values. We are also specifically interested in how and whether justice reinvestment can meet the needs of those social groups that have been adversely affected by mass imprisonment and hyper-incarceration, particularly racial and Indigenous minorities, women and people with mental health issues and cognitive impairment (Cunneen et al., 2013). We argue that justice reinvestment was in its early development strongly tied to civil rights, particularly with the focus on imprisonment and racialization, and social justice for communities where large numbers of residents were recycled in and out of prison

Discovery and Characterization of a Caustic Crossing Microlensing Event in the SMC

We present photometric observations and analysis of the second microlensing event detected towards the Small Magellanic Cloud (SMC), MACHO Alert 98-SMC-1. This event was detected early enough to allow intensive observation of the lightcurve. These observations revealed 98-SMC-1 to be the first caustic crossing, binary microlensing event towards the Magellanic Clouds to be discovered in progress. Frequent coverage of the evolving lightcurve allowed an accurate prediction for the date of the source crossing out of the lens caustic structure. The caustic crossing temporal width, along with the angular size of the source star, measures the proper motion of the lens with respect to the source, and thus allows an estimate of the location of the lens. Lenses located in the Galactic halo would have a velocity projected to the SMC of v^hat ~1500 km/s, while an SMC lens would typically have v^hat ~60 km/s. We have performed a joint fit to the MACHO/GMAN data presented here, including recent EROS data of this event. These joint data are sufficient to constrain the time for the lens to move an angle equal to the source angular radius; 0.116 +/- 0.010 days. We estimate a radius for the lensed source of 1.4 +/- 0.1 R_sun. This yields a projected velocity of v^hat = 84 +/- 9 km/s. Only 0.15% of halo lenses would be expected to have a v^hat value at least as small as this, while 31% of SMC lenses would be expected to have v^hat as large as this. This implies that the lensing system is more likely to reside in the SMC than in the Galactic halo.Comment: 16 pages, including 3 tables and 3 figures; submitted to The Astrophysical Journa

NTR plume modeling

Viewgraphs on nuclear thermal propulsion are presented. Topics covered include computational fluid dynamics (CFD) for plume analysis; molecular fluid dynamics; molecular CFD characteristics; direct-simulation Monte-Carlo (DSMC) method; integration of DSMC and Navier-Stokes computations; and density profiles

Uniformity of V minus Near Infrared Color Evolution of Type Ia Supernovae, and Implications for Host Galaxy Extinction Determination

From an analysis of SNe 1972E, 1980N, 1981B, 1981D, 1983R, 1998bu, 1999cl, and 1999cp we find that the intrinsic V-K colors of Type Ia SNe with multi-color light curve shape (MLCS) parameter -0.4 < Delta < +0.2 suggest a uniform color curve. V-K colors become bluer linearly with time from roughly one week before B-band maximum until one week after maximum, after which they redden linearly until four weeks after maximum. V-H colors exhibit very similar color evolution. V-J colors exhibit slightly more complex evolution, with greater scatter. The existence of V minus near infrared color relations allows the construction of near infrared light curve templates that are an improvement on those of Elias et al. (1985). We provide optical BVRI and infrared JHK photometry of the Type Ia supernovae 1999aa, 1999cl, and 1999cp. SN 1999aa is an overluminous "slow decliner" (with Delta = -0.47 mag). SN 1999cp is a moderately bright SN unreddened in its host. SN 1999cl is extremely reddened in its host. The V minus near infrared colors of SN 1999cl yield A_V = 2.01 +/- 0.11 mag. This leads to a distance for its host galaxy (M 88) in agreement with other distance measurements for members of the Virgo cluster.Comment: 57 pages, 13 postscript figures, to appear in the August 20, 2000, issue of the Astrophysical Journal. Contains updated references and a number of minor corrections dealt with when page proofs were correcte

Exponential suppression of Pauli errors in Majorana qubits via quasiparticle detection

Quasiparticle poisoning errors in Majorana-based qubits are not suppressed by the underlying topological properties, which undermines the usefulness of this proposed platform. This work tackles the issue via quasiparticle measurement. Error-detecting Majorana stabilizer codes are constructed whose stabilizers can be measured by means of Wannier position operators. For a logical qubit encoded in one of these codes, the Pauli error rates are exponentially suppressed in the code distance, a result tied to the exponential localization of Wannier functions. The benefit comes at the cost of a qubit loss rate that increases linearly with the distance, but these can be readily compensated for by a suitable outer code. The framework developed here serves as a basis for understanding how realistic measurements, such as conductance measurements, could be utilized for achieving fault tolerance in these systems. The work also demonstrates that the theory of Wannier functions could lead to error correcting codes beyond the standard stabilizer codes, uncovering another fruitful connection between condensed matter physics and quantum information theory.Comment: 23 pages including appendices, 8 figure

The Psychosocial Consequences of Sports Participation for Individuals with Severe Mental Illness: A Metasynthesis Review

The purpose of the current metasynthesis review was to explore the psychosocial benefits of sport and psychosocial factors which impact on sports participation for individuals with severe mental illness. AMED, CINAHL Plus, Medline, EMBASE, ProQuest Nursing & Allied Health Source, and Science Citation Index were searched from inception until January 2014. Articles included use qualitative methods to examine the psychosocial effects of sports participation in people with severe mental illness. Methodological quality was assessed using the Consolidated Criteria for Reporting Qualitative Studies and a case study tool. Included studies were analysed within a metasynthesis approach. Eight articles involving 56 patients met the inclusion criteria. The results identified the broader and direct psychosocial benefits of sport. Sport provided a ?normal? environment and interactions that were not associated with an individual?s mental illness. Sport provided individuals with a sense of meaning, purpose, belonging, identity, and achievement. Other findings are discussed. Direct psychosocial benefits are a consequence of sports participation for the vast majority of individuals with severe mental illness. Further to this, sports participation was associated with a reduction in social isolation and an increase in social confidence, autonomy, and independence

A dipole anisotropy of galaxy distribution: Does the CMB rest-frame exist in the local universe?

The peculiar motion of the Earth causes a dipole anisotropy modulation in the distant galaxy distribution due to the aberration effect. However, the amplitude and angular direction of the effect is not necessarily the same as those of the cosmic microwave background (CMB) dipole anisotropy due to the growth of cosmic structures. In other words exploring the aberration effect may give us a clue to the horizon-scale physics perhaps related to the cosmic acceleration. In this paper we develop a method to explore the dipole angular modulation from the pixelized galaxy data on the sky properly taking into account the covariances due to the shot noise and the intrinsic galaxy clustering contamination as well as the partial sky coverage. We applied the method to the galaxy catalogs constructed from the Sloan Digital Sky Survey (SDSS) Data Release 6 data. After constructing the four galaxy catalogs that are different in the ranges of magnitudes and photometric redshifts to study possible systematics, we found that the most robust sample against systematics indicates no dipole anisotropy in the galaxy distribution. This finding is consistent with the expectation from the concordance Lambda-dominated cold dark matter model. Finally we argue that an almost full-sky galaxy survey such as LSST may allow for a significant detection of the aberration effect of the CMB dipole having the precision of constraining the angular direction to ~ 20 degrees in radius. Assuming a hypothetical LSST galaxy survey, we find that this method can confirm or reject the result implied from a stacked analysis of the kinetic Sunyaev-Zel'dovich effect of X-ray luminous clusters in Kashlinsky et al. (2008,2009) if the implied cosmic bulk flow is not extended out to the horizon.Comment: 20 pages, 11 figures; 24 pages, added a couple of references and 2 figures. Revised version in response to the referee's comments. Resubmitted to Phys. Rev.