Letter from JC Branner to John Muir 1910 Feb 25

Stanford University, Cal., Feb. 25, 1910 John Muir, Martinez, Cal. Dear Mr. Muir: - I am glad you like the photograph of the Araucaria. You ask about pictures of South American glaciers. The best I can do is to tell you where they are published. The glaciers of the high Andes are best shown and described by Edward Whymper in his “Travels amongst the great Andes of the equator”. New York, 1892. Another good book on the Andes is Sir Martin Conway’s “The Bolivian Andes”, New York and London, 1901. The glaciers of the southern end of the continent are described by Sir Martin Conway in his “Aconcagua and Tierra del Fuego”. London, 1902. E. A. Fitsgerald’s “The highest Andes; a record of the first ascent of Aconcagua and Tupungato”, New York, 1899, gives a good account of the highest peaks, which, by the way, are not far from the railway crossing from Valparaiso to Buenos Aires. I suppose these books can be had in the public libraries of San Francisco. But in case they cannot, I shall be glad to loan you my copies if you will let me know. They are all books that will make you want to start by the next steamer; and they are all by excellent writers and perfectly trustworthy. I f I can be of any service to you at any time, let me know; it will give me great pleasure. Very truly yours, J C Branne

Earth Sculpture or the Origin of Land-forms

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Classification of Complex Polynomial Vector Fields in One Complex Variable

A classification of the global structure of monic and centered one-variable complex polynomial vector fields is presented.Comment: 57 pages, 35 figures, submitted to the Journal of Difference Equations and Application

A Critical Evaluation of Structural Analysis Tools used for the Design of Large Composite Wind Turbine Rotor Blades under Ultimate and Cycle Loading

Rotor blades for 10-20MW wind turbines may exceed 120m. To meet the demanding requirements of the blade design, structural analysis tools have been developed individually and combined with commercial available ones by blade designers. Due to the various available codes, understanding and estimating the uncertainty introduced in the design calculations by using these tools is needed to allow assessment of the effectiveness of any future design modification. For quantifying the introduced uncertainty a reference base was established within INNWIND.EU in which the several structural analysis concepts are evaluated. This paper shows the major findings of the comparative work performed by six organizations (universities and research institutes) participating in the benchmark exercise. The case concerns a 90m Glass/Epoxy blade of a horizontal axis 10MW wind turbine. The detailed blade geometry, the material properties of the constitutive layers and the aero-elastic loads formed the base by which global and local blade stiffness and strength are evaluated and compared. Static, modal, buckling and fatigue analysis of the blade were performed by each partner using their own tools; fully in-house developed or combined with commercially available ones, with its specific structural analysis approach (thin wall theory and finite element models using beam, shell or solid elements) and their preferable analysis type (linear or geometrical non-linear). Along with sectional mass and stiffness properties, the outcome is compared in terms of displacements, stresses, strains and failure indices at the ply level of the blade structure, eigen-frequencies and eigen-modes, critical buckling loads and Palmgren-Miner damage indices due to cycle loading. Results indicate that differences between estimations range from 0.5% to even 40%, depending on the property compared. Modelling details, e.g. load application on the numerical models and assumptions, e.g. type of analysis, lead to these differences. The paper covers these subjects, presenting the modelling uncertainty derived

A Review of Sociological Issues in Fire Safety Regulation

This paper presents an overview of contemporary sociological issues in fire safety. The most obviously social aspects of fire safety—those that relate to the socioeconomic distribution of fire casualties and damage—are discussed first. The means that society uses to mitigate fire risks through regulation are treated next; focusing on the shift towards fire engineered solutions and the particular challenges this poses for the social distribution and communication of fire safety knowledge and expertise. Finally, the social construction of fire safety knowledge is discussed, raising questions about whether the confidence in the application of this knowledge by the full range of participants in the fire safety design and approvals process is always justified, given the specific assumptions involved in both the production of the knowledge and its extension to applications significantly removed from the original knowledge production; and the requisite competence that is therefore needed to apply this knowledge. The overarching objective is to argue that the fire safety professions ought to be more reflexive and informed about the nature of the knowledge and expertise that they develop and apply, and to suggest that fire safety scientists and engineers ought to actively collaborate with social scientists in research designed to study the way people interact with fire safety technology

Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole

N-(2-methoxyphenyl)hydroxylamine is a human metabolite of the industrial and environmental pollutants and bladder carcinogens 2-methoxyaniline (o-anisidine) and 2-methoxynitrobenzene (o-nitroanisole). Here, we investigated the ability of hepatic microsomes from rat and rabbit to metabolize this reactive compound. We found that N-(2-methoxyphenyl)hydroxylamine is metabolized by microsomes of both species mainly to o-aminophenol and a parent carcinogen, o-anisidine, whereas 2-methoxynitrosobenzene (o-nitrosoanisole) is formed as a minor metabolite. Another N-(2-methoxyphenyl)hydroxylamine metabolite, the exact structure of which has not been identified as yet, was generated by hepatic microsomes of rabbits, but its formation by those of rats was negligible. To evaluate the role of rat hepatic microsomal cytochromes P450 (CYP) in N-(2-methoxyphenyl)hydroxylamine metabolism, we investigated the modulation of its metabolism by specific inducers of these enzymes. The results of this study show that rat hepatic CYPs of a 1A subfamily and, to a lesser extent those of a 2B subfamily, catalyze N-(2-methoxyphenyl)hydroxylamine conversion to form both its reductive metabolite, o-anisidine, and o-aminophenol. CYP2E1 is the most efficient enzyme catalyzing conversion of N-(2-methoxyphenyl)hydroxylamine to o-aminophenol