652 research outputs found
How high the temperature of a liquid be raised without boiling?
How high the temperature of a liquid be raised beyond its boiling point
without vaporizing (known as the limit of superheat) is an interesting subject
of investigation. A new method of finding the limit of superheat of liquids is
presented here. The superheated liquids are taken in the form of drops
suspended in visco elastic gel. The nucleation is detected acoustically by a
sensitive piezo-electric transducer, coupled to a multi channel scaler and the
nucleation is observed as a funtion of time and with increase of temperature.
The limit of superheat measured by the present method supersedes all other
measurements and theoretical predictions in reaching closest to the critical
temperature and warrants improved theoretical predictions.Comment: 10 pages, 1 fig. Phys, Rev. E. (2000) in pres
Low-frequency noise reduction of spacecraft structures
Low frequency noise reduction of spacecraft structure
Superheated Microdrops as Cold Dark Matter Detectors
It is shown that under realistic background considerations, an improvement in
Cold Dark Matter sensitivity of several orders of magnitude is expected from a
detector based on superheated liquid droplets. Such devices are totally
insensitive to minimum ionizing radiation while responsive to nuclear recoils
of energies ~ few keV. They operate on the same principle as the bubble
chamber, but offer unattended, continuous, and safe operation at room
temperature and atmospheric pressure.Comment: 15 pgs, 4 figures include
Effect of Flibanserin Treatment on Body Weight in Premenopausal and Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Post Hoc Analysis.
Background: Flibanserin, a 5-HT1A agonist and 5-HT2A antagonist, is indicated for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. This post hoc analysis evaluated the effect of flibanserin treatment on body weight in premenopausal and postmenopausal women with HSDD.
Materials and Methods: This analysis included three 24-week, double-blind, placebo-controlled studies of flibanserin 100 mg each bedtime (qhs) in premenopausal women, a similarly designed study in postmenopausal women, and a 52-week, open-label extension study in premenopausal women.
Results: In a pooled analysis of premenopausal women, mean baseline body mass index (BMI) was 27.0 kg/m2 in the flibanserin group (n = 1227) and 26.8 kg/m2 in the placebo group (n = 1238). Among patients who completed 24 weeks of treatment, least squares (LS) mean weight change was −1.4 kg in the flibanserin group (n = 1010) and −0.1 kg in the placebo group (n = 1066; p \u3c 0.0001). Weight loss ≥5% from baseline was reported in 21.0% of patients who received flibanserin and 7.8% of patients who received placebo; weight loss ≥10% was reported in 3.8% and 2.0% of patients, respectively. In postmenopausal women, mean baseline BMI was 27.7 kg/m2 in the flibanserin group (n = 467) and 27.3 kg/m2 in the placebo group (n = 480). LS mean weight change at week 24 was −1.8 kg in the flibanserin group (n = 385) and −0.1 kg in the placebo group (n = 425; p \u3c 0.0001), with weight loss ≥5% reported in 24.7% and 7.3% of patients, respectively, and weight loss ≥10% reported in 5.2% and 1.7%, respectively. In HSDD patients with \u3e12 months (n = 880) and \u3e18 months (n = 637) of exposure to flibanserin, mean weight change was −1.0 and −1.2 kg, respectively; 25.4% and 26.9% of patients, respectively, experienced weight loss ≥5% from baseline, and 7.8% and 8.4%, respectively, experienced weight loss ≥10%.
Conclusions: Women treated with flibanserin for HSDD may experience weight loss
First Dark Matter Limits from a Large-Mass, Low-Background Superheated Droplet Detector
We report on the fabrication aspects and calibration of the first large
active mass ( g) modules of SIMPLE, a search for particle dark matter
using Superheated Droplet Detectors (SDDs). While still limited by the
statistical uncertainty of the small data sample on hand, the first weeks of
operation in the new underground laboratory of Rustrel-Pays d'Apt already
provide a sensitivity to axially-coupled Weakly Interacting Massive Particles
(WIMPs) competitive with leading experiments, confirming SDDs as a convenient,
low-cost alternative for WIMP detection.Comment: Final version, Phys. Rev. Lett. (in press
Hippocampal Volume Differences in Gulf War Veterans with Current Versus Lifetime Posttraumatic Stress Disorder Symptoms
Background: Decreased hippocampal volume is described in posttraumatic stress disorder (PTSD) and depression. However, it is not known whether it is a risk factor for the development of PTSD or a consequence of PTSD. We sought to determine the effects of PTSD and depressive symptoms on hippocampal volume.
Methods: Clinical and magnetic resonance imaging data were collected in a cross sectional study of 244 GulfWarveterans. Measures included lifetime and current Clinician Administered PTSD Scale, Hamilton Depression Scale, Life Stressor Checklist, and Lifetime Drinking History. Magnetic resonance imaging data were acquired with a 1.5-T scanner and analyzed with automated and semiautomated image processing techniques.
Results: Eighty-two veterans had lifetime PTSD, 44 had current PTSD, and 38 had current depression. In the linear regression analysis, current PTSD symptoms (standardized coefficient B= .25, p =.03) but neither lifetime PTSD symptoms nor current depression were associated with smaller hippocampal volume. Gender, age, history of early life trauma, education, lifetime and current alcohol use, current marijuana use, and treatment with antidepressants did not have independent effects. Participants with chronic PTSD had, on average, a smaller hippocampus compared with those with remitted PTSD.
Conclusions: The finding that current but not lifetime PTSD symptom severity explains hippocampal size raises two possibilities: either a small hippocampus is a risk factor for lack of recovery from PTSD (trait) or PTSD effects on hippocampal volume are reversible once PTSD symptoms remit and the patient recovers (state)
Solitons on the edge of a two-dimensional electron system
We present a study of the excitations of the edge of a two-dimensional
electron droplet in a magnetic field in terms of a contour dynamics formalism.
We find that, beyond the usual linear approximation, the non-linear analysis
yields soliton solutions which correspond to uniformly rotating shapes. These
modes are found from a perturbative treatment of a non-linear eigenvalue
problem, and as solutions to a modified Korteweg-de Vries equation resulting
from a local induction approximation to the nonlocal contour dynamics. We
discuss applications to the edge modes in the quantum Hall effect.Comment: 4 pages, 2 eps figures (included); to appear in Phys. Rev. Letter
Physics on the edge: contour dynamics, waves and solitons in the quantum Hall effect
We present a theoretical study of the excitations on the edge of a
two-dimensional electron system in a perpendicular magnetic field in terms of a
contour dynamics formalism. In particular, we focus on edge excitations in the
quantum Hall effect. Beyond the usual linear approximation, a non-linear
analysis of the shape deformations of an incompressible droplet yields soliton
solutions which correspond to shapes that propagate without distortion. A
perturbative analysis is used and the results are compared to analogous
systems, like vortex patches in ideal hydrodynamics. Under a local induction
approximation we find that the contour dynamics is described by a non-linear
partial differential equation for the curvature: the modified Korteweg-de Vries
equation.
PACS number(s): 73.40.Hm, 02.40.Ma, 03.40.Gc, 11.10.LmComment: 15 pages, 12 embedded figures, submitted to Phys. Rev.
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