Mediapolis: an introduction

The organisation of this workshop has been prompted by concerns with the way media so often seem to get left out of writing on cities and urban politics (rather than vice-versa). We agree with Iveson’s (2007) argument that urban and media studies have much more in the way of shared concerns when it comes to politics than is conventionally thought to be the case. As a result, we are hoping this workshop will create an occasion for urban scholars to meet those studying media, to explore what difference it makes to explicitly consider the place of media practices in making a politics of cities, and conversely, to consider what is left out when such practices are relegated to the background. In certain ways, we are suggesting a contemporary return to something like Robert Park’s inclination in relation to cities and media. In his seminal essay on the natural history of the newspaper, for example (Park, 1925), Park exhibits a style which does not generally seem to distinguish between or oppose the urban and the media when studying politics and democracy. This surely has something to do with Park’s own intellectual period, and the absence of established disciplines in media or urban studies. Yet this is also precisely the point of the workshop: an opportunity for engagement and discussion through a similar sort of pre-disciplinary spirit

The relation between cholesterol and haemorrhagic or ischaemic stroke in the Renfrew/Paisley study

Studies have found little association between cholesterol and overall stroke risk, but this could be attributable to different relations for haemorrhagic and ischaemic stroke. Stroke mortality data from prospective studies cannot usually be divided into stroke subtypes. We have therefore analysed stroke based on hospital admissions, obtained by computerised linkage with acute hospital discharges in Scotland for a large prospective cohort study

Proposed reference models for nitrous oxide and methane in the middle atmosphere

Data from the Stratospheric and Mesospheric Sounder (SAMS) on the Nimbus 7 satellite, for the period from Jan. 1979 - Dec. 1981, are used to prepare a reference model for the long-lived trace gases, methane and nitrous oxide, in the stratosphere. The model is presented in tabular form on seventeen pressure surfaces from 20 to 0.1 mb, in 10 degree latitude bins from 50S to 70N, and for each month of the year. The means by which the data quality and interannual variability, and some of the more interesting globally and seasonally variable features of the data are discussed briefly

Numerical Simulation of Baroclinic Jovian Vortices

We examine the evolution of baroclinic vortices in a time-dependent, nonlinear numerical model of a Jovian atmosphere. The model uses a normal-mode expansion in the vertical, using the barotropic and first two baroclinic modes. Results for the stability of baroclinic vortices on an f plane in the absence of a mean zonal flow are similar to results of Earth vortex models, although the presence of a fluid interior on the Jovian planets shifts the stability boundaries to smaller length scales. The presence of a barotropic mean zonal flow in the interior stabilizes vortices against instability and significantly modifies the finite amplitude form of baroclinic instabilities. The effect of a zonal flow on a form of barotropic instability produces periodic oscillations in the latitude and longitude of the vortex as observed at the level of the cloud tops. This instability may explain some, but not all, observations of longitudinal oscillations of vortices on the outer planets. Oscillations in aspect ratio and orientation of stable vortices in a zonal shear flow are observed in this baroclinic model, as in simpler twodimensional models. Such oscillations are also observed in the atmospheres of Jupiter and Neptune. The meridional propagation and decay of vortices on a β plane is inhibited by the presence of a mean zonal flow. The direction of propagation of a vortex relative to the mean zonal flow depends upon the sign of the meridional potential vorticity gradient; combined with observations of vortex drift rates, this may provide a constraint on model assumption for the flow in the deep interior of the Jovian planets

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus

Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE). However, ES-62 is not suitable for development as a therapy and thus we have designed drug-like small molecule analogues (SMAs) based around its active PC-moiety. To provide proof of concept that ES-62-based SMAs exhibit therapeutic potential in SLE, we have investigated the capacity of two SMAs to protect against nephritis when administered to MRL/Lpr mice after onset of kidney damage. Methods SMAs 11a and 12b were evaluated for their ability to suppress antinuclear antibody (ANA) generation and consequent kidney pathology in MRL/Lpr mice when administered after the onset of proteinuria. Results SMAs 11a and 12b suppressed development of ANA and proteinuria. Protection reflected downregulation of MyD88 expression by kidney cells and this was associated with reduced production of IL-6, a cytokine that exhibits promise as a therapeutic target for this condition. Conclusions SMAs 11a and 12b provide proof of principle that synthetic compounds based on the safe immunomodulatory mechanisms of parasitic worms can exhibit therapeutic potential as a novel class of drugs for SLE, a disease for which current therapies remain inadequate

A statistical technique for determining rainfall over land employing Nimbus-6 ESMR measurements

An empirical method was employed to delineate synoptic scale rainfall over land utilizing Nimbus-6 ESMR measurements

What makes slow samples slow in the Sherrington-Kirkpatrick model

Using results of a Monte Carlo simulation of the Sherrington-Kirkpatrick model, we try to characterize the slow disorder samples, namely we analyze visually the correlation between the relaxation time for a given disorder sample $J$ with several observables of the system for the same disorder sample. For temperatures below $T_c$ but not too low, fast samples (small relaxation times) are clearly correlated with a small value of the largest eigenvalue of the coupling matrix, a large value of the site averaged local field probability distribution at the origin, or a small value of the squared overlap $$. Within our limited data, the correlation remains as the system size increases but becomes less clear as the temperature is decreased (the correlation with$$ is more robust) . There is a strong correlation between the values of the relaxation time for two distinct values of the temperature, but this correlation decreases as the system size is increased. This may indicate the onset of temperature chaos

A central limit theorem for the zeroes of the zeta function

On the assumption of the Riemann hypothesis, we generalize a central limit theorem of Fujii regarding the number of zeroes of Riemann's zeta function that lie in a mesoscopic interval. The result mirrors results of Soshnikov and others in random matrix theory. In an appendix we put forward some general theorems regarding our knowledge of the zeta zeroes in the mesoscopic regime.Comment: 22 pages. Incorporates referees suggestions. Contains minor corrections to published versio

An assessment of health management and biosecurity procedures in marine fish farming in Spain

Marine fish farming in Spain has experienced problems of performance due to losses caused by infectious diseases. Biosecurity and health management are identified by the Food and Agriculture Organization (FAO) as current priorities for proper aquaculture governance. However, they both transcend the responsibility of farmers and require significant resources, concerted action and cooperation. This study presents the analysis of biosecurity practices on marine fish farms, through a questionnaire-based survey on biosecurity procedures and an analysis of health management practices for different stakeholders. The Strengths, Weaknesses, Opportunities, and Threats (SWOT) technique was implemented, which identified the important threats and weaknesses faced by the sector, such as the risk of direct disease transmission between farms, the high likelihood of importing diseases through juvenile shipments, the chronic lack of communication between stakeholders, and the deficient coordination of health strategies. Strengths included awareness of prevention measures and the availability of expertize of health experts at most levels. On the other hand, the availability of experts together with the need to adapt governance to the current production systems were seen as opportunities. Health management measures themselves were actually already found to be adapted to the type of production but they varied between companies (i.e. categorization and diagnosis of mortalities). Nevertheless, the quality of expertize along the value chain provided by private and public laboratories, research institutes, Health Protection Groups, companies and veterinarians was noteworthy. However, there was still a need for all stakeholders involved in marine fish health to improve diagnostics, provide epidemiological information, biosecurity and prevention measures, as well as to promote transparency for better health governance