Barriers to HIV Care for Women of Color Living in the Southeastern US Are Associated with Physical Symptoms, Social Environment, and Self-Determination

HIV-infected women of color (WOC) face particular barriers to accessing HIV medical care. To understand the impact of physical symptoms, social support, and self-determination on barriers to care, we interviewed HIV-infected women of color. HIV-infected WOC (N=141), attending an academic infectious disease clinic for HIV care in North Carolina, completed the Barriers to Care scale and were categorized as reporting a history of low (less than four of eleven barriers) or high (five or more) barriers to care. Binomial regression was used to estimate prevalence ratios and risk differences of reported barriers to care and its correlates such as depression, anxiety, illness-severity, psychological abuse, social support, treatment-specific social support, and self-determination (autonomy, relatedness, competency). A lower risk of reporting five or more barriers to care was associated with higher levels of autonomy (PR=0.93, 95% CI: 0.89, 0.96), relatedness (PR=0.92, 95% CI: 0.89, 0.94), competency (PR=0.93, 95% CI: 0.87, 0.98), and social support (PR=0.24, 95% CI: 0.81, 0.81). Depression, illness severity, and psychological abuse were associated with a greater risk of having five or more barriers to care. There are multiple social and psychological factors that contribute to perceived barriers to HIV care among WOC in the southeastern USA. Interventions that promote social support and increase individual self-determination have the potential to improve access to HIV care for WOC

X-ray Crystallographic Studies of a Bimetallic \u3cem\u3ecis-\u3c/em\u3eMo(CO)\u3csub\u3e4\u3c/sub\u3e(PPh\u3csub\u3e2\u3c/sub\u3eNH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eN=CHC\u3csub\u3e6\u3c/sub\u3eH\u3csub\u3e4\u3c/sub\u3e-o-O)\u3csub\u3e2\u3c/sub\u3eCu Complex, the Starting Material, \u3cem\u3ecis-\u3c/em\u3eMo(CO)\u3csub\u3e4\u3c/sub\u3e(PPh\u3csub\u3e2\u3c/sub\u3eCl)\u3csub\u3e2\u3c/sub\u3e, and the Reaction Intermediates \u3cem\u3ecis-\u3c/em\u3eMo(CO)\u3csub\u3e4\u3c/sub\u3e(PPh\u3csub\u3e2\u3c/sub\u3eNH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eNH\u3csub\u3e2\u3c/sub\u3e2) \u3csub\u3e2\u3c/sub\u3e and \u3cem\u3ecis-\u3c/em\u3eMo(CO)\u3csub\u3e4\u3c/sub\u3e (PPh\u3csub\u3e2\u3c/sub\u3eNH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eCH\u3csub\u3e2\u3c/sub\u3eN=CHC\u3csub\u3e6\u3c/sub\u3eH\u3csub\u3e4\u3c/sub\u3e\u3cem\u3e-o-\u3c/em\u3eOH)\u3csub\u3e2\u3c/sub\u3e

In this paper, we report the crystal structures of a bimetallic trans-[cis-Mo(CO)4(PPh2NHCH2CH2N=CH(o-C6H4O)]]Cu Complex (monoclinic space group P2/c), the cis-Mo(CO)4(PPh2Cl)2 starting material, (monoclinic space group C2/c) and the two reaction intermediates cis-Mo(CO)4(PPh2NHCH2CH2N=CH(o-C6H4OH)2 (orthorhombic space group P2(1)2(1)2). The dihedral angle between the o-salicylaldiminato groups in the bimetallic complex (36.32(18)°) is considerable large than that in the previously reported trans-[cis-Mo(CO)4-[PPh2NHCH2CH2N=CH(o-C6H4O)]2]Ni complex (12.6°) demonstrating that the coordination preferences of the metal dications have significant effects on the conformations of the bimetallic complexes. The orientations of the phosphinamide ligands bimetallic complex are quite different than are those in the intermediates due to the steric restraints imposed by chelation to the Cu2+