Giant magnons in TsT-transformed AdS_5 x S^5

We consider giant magnons propagating in a \gamma-deformed AdS_5 x S^5 background obtained from AdS_5 x S^5 by means of a chain of TsT transformations. We point out that in the light-cone gauge and in the infinite J limit the deformed and undeformed string models share the same magnon dispersion relation, the \su(2|2)\oplus \su(2|2)-invariant world-sheet S-matrix and the dressing factor. The \gamma-dependence in the limit is only due to different level-matching conditions. We consider the reduction of the deformed model to R x S^3 and determine the leading \gamma-dependence of the dispersion relation for a finite J giant magnon.Comment: 21 pages; v2: minor corrections (missing 2\pi factor inserted, inequalities corrected); 2 references adde

Relocalization of Translation Termination and Ribosome Recycling Factors to Stress Granules Coincides with Elevated Stop-Codon Readthrough and Reinitiation Rates upon Oxidative Stress

Upon oxidative stress, mammalian cells rapidly reprogram their translation. This is accompanied by the formation of stress granules (SGs), cytoplasmic ribonucleoprotein condensates containing untranslated mRNA molecules, RNA-binding proteins, 40S ribosomal subunits, and a set of translation initiation factors. Here we show that arsenite-induced stress causes a dramatic increase in the stop-codon readthrough rate and significantly elevates translation reinitiation levels on uORF-containing and bicistronic mRNAs. We also report the recruitment of translation termination factors eRF1 and eRF3, as well as ribosome recycling and translation reinitiation factors ABCE1, eIF2D, MCT-1, and DENR to SGs upon arsenite treatment. Localization of these factors to SGs may contribute to a rapid resumption of mRNA translation after stress relief and SG disassembly. It may also suggest the presence of post-termination, recycling, or reinitiation complexes in SGs. This new layer of translational control under stress conditions, relying on the altered spatial distribution of translation factors between cellular compartments, is discussed