a-d.

<p>Bland-Altman plots to show a) Inter-observer agreement of central retinal thickness; b) Inter-scan agreement of central retinal thickness; c) Inter-observer agreement of foveal width; d) Inter-scan agreement of foveal width. All measurements presented in microns. Red line indicates mean difference, d between values. Limits of Agreement (d+1.96s) represented by upper and lower grey dashed lines respectively.</p

Percentage of individuals with exponential, ring-like or central dip MP spatial profile phenotypes within each ethnic group (upper graph).

<p>Percentage of white, South Asian and black individuals within each MP spatial profile phenotype (lower graph).</p

a and b.

<p>Measurement of foveal width. Maximum retinal thickness nearest to the foveal reflex on nasal (a) and temporal side identified from the thickness profile. Foveal width was measured in microns using the inbuilt manual calipers (b).</p

Variation in mean MPOD (primary y-axis) plotted against retinal eccentricity (x-axis) according to spatial profile phenotype with corresponding inner retinal layer thickness plotted on the secondary y-axis.

<p>Error bars indicate ±SD. Although MPOD at 0° and 0.8° is increased in the ring-like and central dip compared to the exponential spatial profile groups, there is no significant difference in inner retinal layer thickness between the groups.</p

Inter-scan agreement of thickness of retinal layers in microns at 0, 2 and 5° from foveal centre.

<p>Retinal thickness refers to thickness from the inner limiting membrane to the external limiting membrane. Limits of Agreement are equal to the mean difference ± Coefficient of Repeatability (CoR).</p><p>Inter-scan agreement of thickness of retinal layers in microns at 0, 2 and 5° from foveal centre.</p

Positioning of software caliper for lateral retinal thickness measurement.

<p>Positioning of software caliper for lateral retinal thickness measurement.</p

Mean ± SD retinal thickness, foveal width and foveal volume, inner and outer plexiform layers per ethnic group and results of two-way analysis of covariance showing between-subjects effects of ethnicity with mean spherical error as covariate (results for gender analysis not shown).

<p>Mean ± SD retinal thickness, foveal width and foveal volume, inner and outer plexiform layers per ethnic group and results of two-way analysis of covariance showing between-subjects effects of ethnicity with mean spherical error as covariate (results for gender analysis not shown).</p

Mean ± SD MPOD at 0°, 0.8° and MPODint (0 to 1.8) per ethnic group and gender.

<p>Results of two-way analysis of covariance between-subjects effects of ethnicity are presented.</p

Patient demographics.

<p>Where data for three groups are given, P values refer to probabilities that the parameter differs significantly between the 3 groups, otherwise the probabilities refer to differences between the two diabetic groups.</p>*<p>indicates a statistically significant p-value of ≤0.05.</p

Baseline data for well-controlled (HbA1c ≤7.5%) and poorly-controlled (HbA1c >7.5%) diabetic patients (including both T1DM and T2DM) for all ocular parameters.

<p>Aberrations were measured for 6 mm pupils.</p>*<p>indicates a statistically significant p-value of ≤0.05.</p