12 research outputs found
Hybrid bright-field and hologram imaging of cell dynamics
Volumetric observation is essential for understanding the details of complex biological phenomena.
In this study, a bright-field microscope, which provides information on a specific 2D plane, and a
holographic microscope, which provides information spread over 3D volumes, are integrated to acquire
two complementary images simultaneously. The developed system was successfully applied to capture
distinct T-cell adhesion dynamics on inflamed endothelial layers, including capture, rolling, crawling,
transendothelial migration, and subendothelial migration.113Ysciescopu
Flapping dynamics of a flexible plate with Navier slip
Seaweed and fish have slippery outer surfaces because of the secretion of a layer of mucus. Navier slip arises when the component of the tangential velocity at a wall is proportional to the strain. The hydrodynamics of a three-dimensional flexible plate with Navier slip was explored by using the immersed boundary method in an effort to scrutinize the effects on plate hydrodynamics of a slip boundary mimicking the mucus layers of seaweed and fish. For comparison, simulations with the no-slip condition were also performed. Two cases were chosen for simulation: a flexible plate with a fixed leading edge and a flexible plate with a heaving leading edge in a uniform flow. For the fixed plate, the velocity gradient and the total drag were determined to examine the influence of the slip surface. Drag was significantly reduced by the slip. The slip surface lessens the velocity gradient near the wall and suppresses the flapping motion. The drag reduction process was characterized by using the distributions of vorticity and pressure. The hydrodynamics of the heaving flexible plate with Navier slip was explored in terms of thrust generation. The flapping motion was mainly governed by the input heaving condition and a large form drag was exerted on the flexible plate. The net thrust, input power, and Froude efficiency were determined as a function of the bending rigidity. A large net thrust for the heaving plate was generated by the slip. The velocity ratio was employed to interpret the correlation between the slip velocity and the flapping motion.11Nsciescopu
Self-focusing Multibump Standing Waves in Expanding Waveguides
Let M be a smooth k-dimensional closed submanifold of R(N), N >= 2, and let Omega(R) be the open tubular neighborhood of radius 1 of the expanded manifold M(R) := {Rx : x is an element of M}. For R sufficiently large we show the existence of positive multibump solutions to the problem -Delta u + lambda u = f(u) in Omega(R), u = 0 on partial derivative Omega(R). The function f is superlinear and subcritical, and lambda > -lambda(1), where lambda(1) is the first Dirichlet eigenvalue of -Delta in the unit ball in R(N-k)
Magnetic evaluation of microstructure changes in 9Cr-1Mo and 2.25Cr-1Mo steels using electromagnetic sensors
This paper presents results from a multi-frequency electromagnetic sensor used to evaluate the microstructural changes in 9Cr-1Mo and 2.25Cr-1Mo power generation steels after tempering and elevated temperature service exposure. Electromagnetic sensors detect microstructural changes in steels due to changes in the relative permeability and resistivity. It was found that the low frequency inductance value is particularly sensitive to the different relative permeability values of both steels in the different microstructural conditions. The changes in relative permeability have been quantitatively correlated with the microstructural changes due to tempering and long-term thermal exposure, in particular to changes in martensitic/bainitic lath size and number density of carbide precipitates that determine the mean free path to reversible domain wall motion. The role of these microstructural features on pinning of magnetic domain wall motion is discussed