Development of Acute Promyelocytic Leukemia in a Patient With Gouty Arthritis on Long Term Colchicine

Colchicine is a frequently used drug in rheumatological diseases. Acute promyelocytic leukemia developed in a patient who used colchicine for gouty arthritis since 10 years is presented and the possible relation between the long term use of colchicine and hematological malignancies is discussed

The frequency and characteristics of idiopathic osteosclerosis and condensing osteitis lesions in a Turkish patient population

Objectives: The objective of this study was to investigate the frequencies of idiopathic osteosclerosis (IO) and condensing osteitis (CO) in a Turkish patient population with respect to age and sex, in addition to shape, localization, and the dental relationship of IO and CO lesions. Patients and methods: A retrospective study was performed using panoramic radiographs of 6,154 patients ranging in age from 5 to 69 subjected to dental treatment. Descriptive characteristics of radiopacities, including shape, localization, and dental relationship were recorded. The Chi-squared test was used. Results: There were 238 radiopacities detected, 185 IO lesions in 150 (2.44 %) subjects (96 female, 54 male and mean age: 26.2), and 53 CO lesions in 50 (0.81 %) subjects (27 female, 23 male and mean age: 32.8). Both IO and CO lesions were found to be higher in number among females when compared to males. However, this difference was statistically significant only for IO lesions (p<0.001). The frequency of IO lesions was found to be significantly higher in the 3rd and 4th decades of life (20-39 years) than in other decades (p<0.001). On the other hand, the frequency of CO lesions was the similar in the age ranges of 20-39 years and 40-69 years, and its frequency in these periods was statistically higher than in the 1st and 2nd decades of life (p<0.01). Conclusion: Our results point to the low IO and CO frequency among the Turkish population. In addition, our findings support the theory that IO lesions are developmental variations of normal bone architecture unrelated to a local stimulant and CO lesions could be considered reactive formations related to teeth with severe caries, restoration, or pulpitis

Necessity of analgesics prescription after tooth extraction

Introduction. For patients and surgeons, pain and discomfort associated with dento-alveolar surgery can be a frightening prospect. This study was aimed to check whether prescription of analgesics is necessary or not after simple extraction of the mandibular third molars. Material and methods. Seventy-six dental outpatients undergoing uncomplicated extraction of both mandibular third molars teeth served as subjects. After extraction on the first side, patients received either naproxen sodium 550 mg orally or a placebo. The order of the drugs was reversed during extraction on side two. The postoperative pain was scored with a six-point category rating scala. The obtained data were analyzed with Mann-Whitney U-test. Results. The sum of the pain intensity for hours 2 through 8 was less for the group that received sodium naproxen. For hours 8-24, the sum of the pain intensity was less for the placebo group but this difference was not statistically different. Conclusion. This study shows that uncomplicated tooth extraction did not cause a significant postoperative pain and there was no need to prescribe analgesics for such cases

Prognosis of a case with paresthesia associated with prolonged touching of an endodontic paste to the inferior alveolar nerve

Paresthesia is described as an abnormal sensation, such as burning, pricking, tickling, tingling, formication or numbness. Several conditions can cause paresthesia. This article presents a case of paresthesia caused by the extrusion of endodontic paste (Endomethasone®) into the mandibular canal. The clinical manifestations comprised the numbness on the right side of the mandible and right lower lip, appearing after endodontic treatment. After a mandibular block and infiltration anesthesia a mucoperiostal flap was raised and the extruded Endomethasone® was removed successfully. A therapy with antibiotic, B vitamin complex and an analgesic were prescribed. The patient reported an improvement in pain and headache after one week later and in burning after two weeks. After a four months follow-up, she became symptom free. Also sixteen months later she had any symptoms. Normalization of sensation shows that the neurotoxic effects of Endomethasone® are reversible after more than one month from the first touch of Endomethasone® to the inferior alveolar nerv

CALCIFYING EPITHELIAL ODONTOGENIC TUMOR: A CASE REPORT

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic tumor. It was firstly described by Pindborg, and thus, is also referred to as the “Pindborg tumor.” CEOTaccounts for approximately 0.4-3 % of all the odontogenic tumors. Pindborg tumor is a benign but locally aggressive. It usually presents as a hard painless mass, generally affecting the mandible. Epithelial calcified odontogenic tumor usually found in the posterior mandibular bone, and it shares many features with the ameloblastoma. In this case report, clinical, radiological findings and surgical treatment of the patient with Pindborg tumor were presented

Placenta accreta spectrum surgery with the Joel Cohen incision for abdominal access: a single-center experience

Objectives: Placenta accreta spectrum (PAS) is usually treated by hysterectomy performed through a midline incision. We hypothesize that PAS surgery can be performed through a Joel-Cohen incision with adequate sight and safety. Material and methods: The data on women having a hysterectomy due to PAS between 2013–2021 was collected retrospectively. Operation length, baby’s pre-delivery general anesthesia exposure time, transfusion rates, complication rates, postoperative admission to the intensive care unit (ICU), postoperative hospital stay, and neonatal outcomes were collected. In addition, the data investigated whether the operation was performed under emergent conditions and in the early (2013–2016) or late (2017–2021) years. Results: 161 patients met the inclusion criteria. The median gestational age at delivery was 34 weeks (27–39). The mean operation length was 150 minutes (75–420), and the anesthesia–to–delivery interval was 32 minutes (5–95). Twenty-three (14%) patients did not receive any blood product, 73 (45%) received less than three packs of erythrocyte, and only seven (4%) had a massive transfusion. Bladder injuries occurred in 24 (15%). Preoperative anemia, hypogastric artery ligation, transfusion, ICU admission, and maternal and neonatal complications were more frequent in emergent cases. Comparison between the early and late groups showed a decrease in the rate of anemia, maternal ICU admission, hypogastric artery ligation, and neonatal complications. In addition, infectious complications were relatively rare in all groups. Conclusions: The Joel-Cohen incision and bladder dissection before the baby's delivery reduce transfusion rates and avoid midline incision, which is prone to complications and unpleasant cosmetic appearance while performing a hysterectomy for PAS surgery

Supernumerary, ectopic tooth in the maxillary antrum presenting with recurrent haemoptysis

<p>Abstract</p> <p>Background</p> <p>Ectopic eruption of teeth in non-dental sites is a rare phenomenon and can present in a variety of ways such as chronic or recurrent sinusitis, sepsis, nasolacrimal duct obstruction, headaches, ostiomeatal complex disease and facial numbness. However, presentation of such patients with recurrent haemoptysis has not been described in the literature so far. We have described a case of an ectopic, supernumerary molar tooth in the maxillary antrum in a patient who initially presented with haemoptysis.</p> <p>Case presentation</p> <p>A 45-year-old male presented with a 2-month history of episodic haemoptysis. A pedunculated growth from the inferior nasal turbinate was seen with fibre-optic visualization. Although the patient was empirically started on antibiotic and anti-allergic therapy, there was no improvement after a few weeks and the patient had recurrent episodes of haemoptysis. Fibre-optic visualization was repeated showing bilateral osteomeatal erythema. Computed tomography scan of the paranasal sinuses demonstrated complete opacification of the left maxillary antrum along with a focal area of density comparable to bone. An ectopic, supernumerary molar tooth was found in the left maxillary antrum on endoscopic examination and subsequently removed. In addition, copious purulent discharge was seen. Post-operatively, the patient was treated with a 10-day course of oral amoxicillin-clavulanate. On follow-up, he reported resolution of symptoms.</p> <p>Conclusion</p> <p>Recurrent haemoptysis has not been described as a presentation for a supernumerary, ectopic tooth in literature before. We recommend that in patients with sinusitis-type of opacification of maxillary antrum and whose condition is refractory to conventional medical treatment, consideration should be given to the investigation of possible underlying anomalies as the cause of such symptoms. Presence of foreign bodies and ectopic teeth in paranasal sinuses can be reliably excluded with the use of appropriate radiological imaging and endoscopic examination.</p