Full cost per POC test^*.

*<p>Assumes the 3% of failures are not retested or full labor costs are incurred for repeating test. Minor labor savings are possible with repeat testing immediately after the failure.</p

Material costs per POC test^*.

*<p>Exchange rate = 7.5 R/$US. All costs include South Africa's value-added tax (14%). Glove cost per test based on 500 powder-free gloves for R29 (National Health Laboratory System). Sample collection kit based on price quote from Alere R501.60 per 100). Test cartridge cost based on price quote from Alere (R5,969.04 for package of 100). Printing cost per test based on R1114.92 per package of printer rolls (10 rolls per pack, 50 reports per roll from Printer documentation).</p

Salary cost per working hour and per test.

<p>Salary cost per working hour and per test.</p

Staff time per POC test.

<p>Staff time per POC test.</p

Average resource utilization and selected unit costs for the study sample (<i>n</i> = 2,160) over 12 mo from the date of down-referral eligibility.

a<p>Costs were converted to US dollars at a rate of R8.40 to US$1.00.</p

Costs for daily quality control.

<p>Costs for daily quality control.</p

Equipment costs*.

<p>Equipment costs*.</p

Number of tests completed per day and per year.

<p>Note: Days per month from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0035444#pone-0035444-t004" target="_blank">Table 4</a>.</p

Criteria for assigning HIV treatment outcomes.

<p>Criteria for assigning HIV treatment outcomes.</p

Characteristics of ART patients at the time of eligibility for down-referral to nurse-managed care.

a<p>These characteristics were matched between the two samples.</p>b<p>Note that 15.4% of participants in the treatment-initiation sample and 11.5% in the down-referral sample did not have baseline CD4 counts reported.</p><p>IQR, inter-quartile range.</p