Metastatic bronchogenic carcinoma to the mandible

A case of a metastasis of adenocarcinoma of the lung to a secondary site in the mandible, in a 53-year-old woman, is presented. The patient complained of trismus, swelling and numbness over the left side of face for 8-weeks. Examination revealed limited left condylar mobility, a firm tender swelling the angle of the mandible and paresthesia of the left inferior alveolar nerve. Computed Tomography revealed an osteolytic lesion in the left angle and ascending ramal region suggestive of a malignant tumor. Her chest radiograph findings were of a diffuse homogenous opacification with ipsilateral pleural effusion pointing to a pneumonic process. Histology features were of moderately differentiated adenocarcinoma. A search for the primary included a bronchial biopsy which revealed, the primary lesion was from the lung. This rare case highlights the difficulty and challenges in making the diagnosis clinicians may encounter in establishing the primary site of metastatic disease. There is need to develop high index of suspicion with regards to metastasis to the Craniofacial and mandibular bones. Multidisciplinary team approach is recommended when dealing with such patients.Keywords: Bronchogenic Carcinoma, Metastasis, Mandibl

Ipsilateral Synchronous Manifestation of an HIV-Infection Associated Plunging Ranula and Sublingual Salivary Gland Sialocoele: A Review and Case Report

Plunging ranula is a rare lesion and even more in HIV-infected patients. There has been only one case documented in a 15-year old that had the vertical form HIV-infection. We report a plunging ranula occurring simultaneously with a sublingual salivary gland sialocoele as two separate lesions in an HIV-infected female patient.Keywords: Ranula, salivary glands  

Case Report: Calcifying epithelial odontogenic tumor (Pindborg tumor)

Calcifying epithelial odontogenic tumor is rare. It may mimic both a non-odontogenic or odontogenic tumour causing expansion and destruction of the involved bones.  Histopathology is the main stay for definitive diagnosis. Treatment options vary from enucleation tohemi -mandibulectomy or maxillectomy followed by reconstruction. We present a young female patient with CEOTin an attempt to create awareness in its management and to provide evidence based recommendationsto add on to the existing literature on this rare tumour.Keywords: Calcifying epithelial odontogenic tumor, Pindborg tumor, CEO

DNA Photodamage and Repair: Computational Photobiology in Action

International audienc