19 research outputs found
On-Orbit Performance of the Helioseismic and Magnetic Imager Instrument onboard the Solar Dynamics Observatory
The Helioseismic and Magnetic Imager (HMI) instrument is a major component of
NASA's Solar Dynamics Observatory (SDO) spacecraft. Since beginning normal
science operations on 1 May 2010, HMI has operated with remarkable continuity,
e.g. during the more than five years of the SDO prime mission that ended 30
September 2015, HMI collected 98.4% of all possible 45-second velocity maps;
minimizing gaps in these full-disk Dopplergrams is crucial for helioseismology.
HMI velocity, intensity, and magnetic-field measurements are used in numerous
investigations, so understanding the quality of the data is important. We
describe the calibration measurements used to track HMI performance and detail
trends in important instrument parameters during the mission. Regular
calibration sequences provide information used to improve and update the HMI
data calibration. The set-point temperature of the instrument front window and
optical bench is adjusted regularly to maintain instrument focus, and changes
in the temperature-control scheme have been made to improve stability in the
observable quantities. The exposure time has been changed to compensate for a
15% decrease in instrument throughput. Measurements of the performance of the
shutter and tuning mechanisms show that they are aging as expected and continue
to perform according to specification. Parameters of the tunable-optical-filter
elements are regularly adjusted to account for drifts in the central
wavelength. Frequent measurements of changing CCD-camera characteristics, such
as gain and flat field, are used to calibrate the observations. Infrequent
expected events, such as eclipses, transits, and spacecraft off-points,
interrupt regular instrument operations and provide the opportunity to perform
additional calibration. Onboard instrument anomalies are rare and seem to occur
quite uniformly in time. The instrument continues to perform very well.Comment: 50 pages, 18 figures, 20 table
The James Webb Space Telescope Mission
Twenty-six years ago a small committee report, building on earlier studies,
expounded a compelling and poetic vision for the future of astronomy, calling
for an infrared-optimized space telescope with an aperture of at least .
With the support of their governments in the US, Europe, and Canada, 20,000
people realized that vision as the James Webb Space Telescope. A
generation of astronomers will celebrate their accomplishments for the life of
the mission, potentially as long as 20 years, and beyond. This report and the
scientific discoveries that follow are extended thank-you notes to the 20,000
team members. The telescope is working perfectly, with much better image
quality than expected. In this and accompanying papers, we give a brief
history, describe the observatory, outline its objectives and current observing
program, and discuss the inventions and people who made it possible. We cite
detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space
Telescope Overview, 29 pages, 4 figure
Wavelength Dependence of the Helioseismic and Magnetic Imager (HMI) Instrument onboard the Solar Dynamics Observatory (SDO)
Rebooting Mediation by Detaching from the Illusions of Neutrality, Just Outcomes and Balanced Power
Giant-cell tumours of bone of the hand and wrist: a review of imaging findings and differential diagnoses
Astrogliosis in CNS Pathologies: Is There A Role for Microglia?
Astrogliosis, a cellular reaction with specific structural and functional characteristics, represents a remarkably homotypic response of astrocytes to all kinds of central nervous system (CNS) pathologies. Astrocytes play diverse functions in the brain, both harmful and beneficial. Mounting evidence indicates that astrogliosis is an underlying component of a diverse range of diseases and associated neuropathologies. The mechanisms that lead to astrogliosis are not fully understood, nevertheless, damaged neurons have long been reported to induce astrogliosis and astrogliosis has been used as an index for underlying neuronal damage. As the predominant source of proinflammatory factors in the CNS, microglia are readily activated under certain pathological conditions. An increasing body of evidence suggests that release of cytokines and other soluble products by activated microglia can significantly influence the subsequent development of astrogliosis and scar formation in CNS. It is well known that damaged neurons activate microglia very quickly, therefore, it is possible that activated microglia contribute factors/mediators through which damaged neuron induce astrogliosis. The hypothesis that activated microglia initiate and maintain astrogliosis suggests that suppression of microglial overactivation might effectively attenuate reactive astrogliosis. Development of targeted anti-microglial activation therapies might slow or halt the progression of astrogliosis and, therefore, help achieve a more beneficial environment in various CNS pathologies