A novel method for the injection and manipulation of magnetic charge states in nanostructures

Realising the promise of next-generation magnetic nanotechnologies is contingent on the development of novel methods for controlling magnetic states at the nanoscale. There is currently demand for simple and flexible techniques to access exotic magnetisation states without convoluted fabrication and application processes. 360 degree domain walls (metastable twists in magnetisation separating two domains with parallel magnetisation) are one such state, which is currently of great interest in data storage and magnonics. Here, we demonstrate a straightforward and powerful process whereby a moving magnetic charge, provided experimentally by a magnetic force microscope tip, can write and manipulate magnetic charge states in ferromagnetic nanowires. The method is applicable to a wide range of nanowire architectures with considerable benefits over existing techniques. We confirm the method's efficacy via the injection and spatial manipulation of 360 degree domain walls in Py and Co nanowires. Experimental results are supported by micromagnetic simulations of the tip-nanowire interaction.Comment: in Scientific Reports (2016

Olfactory variation in mouse husbandry and its implications for refinement and standardisation: UK survey of non-animal scents

With their highly sensitive olfactory system, the behaviour and physiology of mice are not only influenced by the scents of conspecifics and other species, but also by many other chemicals in the environment. The constraints of laboratory housing limit a mouse’s capacity to avoid aversive odours that could be present in the environment. Potentially odorous items routinely used for husbandry procedures, such as sanitizing products and gloves, could be perceived by mice as aversive or attractive, and affect their behaviour, physiology and experimental results. A survey was sent to research institutions in the UK to enquire about husbandry practices that could impact on the olfactory environment of the mouse. Responses were obtained from 80 individuals working in 51 institutions. Husbandry practices varied considerably. Seventy percent of respondents reported always wearing gloves for handling mice, with nitrile being the most common glove material (94%) followed by latex (23%) and vinyl (14%). Over six different products were listed for cleaning surfaces, floors, anaesthesia and euthanasia chambers and behavioural apparatus. In all cases Trigene™ (now called Anistel™) was the most common cleaning product used (43, 41, 40 and 49%, respectively). Depending on the attribute considered, between 7 and 19% of respondents thought that cleaning products definitely, or were likely to, have strong effects on standardization, mouse health, physiology or behaviour. Understanding whether and how these odours affect mouse welfare will help to refine mouse husbandry and experimental procedures through practical recommendations, to improve the quality of life of laboratory animals and the experimental data obtained

Extragalactic Zeeman Detections in OH Megamasers

We have measured the Zeeman splitting of OH megamaser emission at 1667 MHz from five (ultra)luminous infrared galaxies ([U]LIRGs) using the 305 m Arecibo telescope and the 100 m Green Bank Telescope. Five of eight targeted galaxies show significant Zeeman-splitting detections, with 14 individual masing components detected and line-of-sight magnetic field strengths ranging from ~0.5-18 mG. The detected field strengths are similar to those measured in Galactic OH masers, suggesting that the local process of massive star formation occurs under similar conditions in (U)LIRGs and the Galaxy, in spite of the vastly different large-scale environments. Our measured field strengths are also similar to magnetic field strengths in (U)LIRGs inferred from synchrotron observations, implying that milligauss magnetic fields likely pervade most phases of the interstellar medium in (U)LIRGs. These results provide a promising new tool for probing the astrophysics of distant galaxies.Comment: 32 pages, 14 figures, 8 tables. Accepted for publication in The Astrophysical Journal v680n2, June 20, 2008; corrected 2 typo

Measurement of the Integrated Faraday Rotations of BL Lac Objects

We present the results of multi-frequency polarization VLA observations of radio sources from the complete sample of northern, radio-bright BL Lac objects compiled by H. Kuhr and G. Schmidt. These were used to determine the integrated rotation measures of 18 objects, 15 of which had never been measured previously, which hindered analysis of the intrinsic polarization properties of objects in the complete sample. These measurements make it possible to correct the observed orientations of the linear polarizations of these sources for the effect of Faraday rotation. The most probable origin for Faraday rotation in these objects is the Galactic interstellar medium. The results presented complete measurements of the integrated rotation measures for all 34 sources in the complete sample of BL Lac objects.Comment: 9 pages, 7 figure

Peri-operative pulse oximetry in low-income countries: a cost–effectiveness analysis

Abstract Objective: To evaluate the cost–effectiveness of pulse oximetry – compared with no peri-operative monitoring – during surgery in low-income countries. Methods: We considered the use of tabletop and portable, hand-held pulse oximeters among patients of any age undergoing major surgery in low-income countries. From earlier studies we obtained baseline mortality and the effectiveness of pulse oximeters to reduce mortality. We considered the direct costs of purchasing and maintaining pulse oximeters as well as the cost of supplementary oxygen used to treat hypoxic episodes identified by oximetry. Health benefits were measured in disability-adjusted life-years (DALYs) averted and benefits and costs were both discounted at 3% per year. We used recommended cost–effectiveness thresholds – both absolute and relative to gross domestic product (GDP) per capita – to assess if pulse oximetry is a cost–effective health intervention. To test the robustness of our results we performed sensitivity analyses. Findings: In 2013 prices, tabletop and hand-held oximeters were found to have annual costs of 310 and 95 United States dollars (US$), respectively. Assuming the two types of oximeter have identical effectiveness, a single oximeter used for 22 procedures per week averted 0.83 DALYs per annum. The tabletop and hand-held oximeters cost US$ 374 and US$115 per DALY averted, respectively. For any country with a GDP per capita above US$ 677 the hand-held oximeter was found to be cost–effective if it prevented just 1.7% of anaesthetic-related deaths or 0.3% of peri-operative mortality. Conclusion: Pulse oximetry is a cost–effective intervention for low-income settings

ROSAT and ASCA observations of the Crab-Like Supernova Remnant N157B in the Large Magellanic Cloud

We report the results of ROSAT and ASCA X-ray observations of the supernova remnant N157B (or 30 Dor B, SNR 0539-69.1) in the Large Magellanic Cloud. For comparison, we also briefly describe the results on SNR 0540-69.3, the only confirmed Crab-like remnant in the Cloud. The X-ray emission from N157B can be decomposed into a bright comet-shaped feature, superimposed on a diffuse emission region of a dimension $\sim 20$ pc. The flat and nearly featureless spectrum of the remnant is distinctly different from those of young shell-like remnants, suggesting a predominantly Crab-like nature of N157B. Characterized by a power law with an energy slope $\sim 1.5$, the spectrum of N157B above $\sim 2$ keV is, however, considerably steeper than that of SNR 0540-69.3, which has a slope of $\sim 1.0$. At lower energies, the spectrum of N157B presents marginal evidence for emission lines, which if real most likely arise in hot gas of the diffuse emission region. The hot gas has a characteristic thermal temperature of 0.4-0.7 keV. No significant periodic signal is detected from N157B in the period range of $3 \times 10^{-3}-2000$ s. The pulsed fraction is $\lesssim 9$ (99% confidence) in the $2-7$ keV range. We discuss the nature of the individual X-ray components. In particular, we suggest that the synchrotron radiation of relativistic particles from a fast-moving ($\sim 10^3 km s^{-1}$) pulsar explains the size, morphology, spectrum, and energetics of the comet-shaped X-ray feature. We infer the age of the remnant as $\sim 5 \times 10^3$ yrs. The lack of radio polarization of the remnant may be due to Faraday dispersion by foreground \ion{H}{2} gas.Comment: To be published in The Astrophysical Journal, 21 pages, plus 11 images in the PS, GIF, or jpeg format. Postscript files of images are available at http://www.astro.nwu.edu/astro/wqd/paper/n157b

The COINS Sample - VLBA Identifications of Compact Symmetric Objects

We present results of multifrequency polarimetric VLBA observations of 34 compact radio sources. The observations are part of a large survey undertaken to identify CSOs Observed in the Northern Sky (COINS). Compact Symmetric Objects (CSOs) are of particular interest in the study of the physics and evolution of active galaxies. Based on VLBI continuum surveys of ~2000 compact radio sources, we have defined a sample of 52 CSOs and CSO candidates. In this paper, we identify 18 previously known CSOs, and introduce 33 new CSO candidates. We present continuum images at several frequencies and, where possible, images of the polarized flux density and spectral index distributions for the 33 new candidates and one previously known but unconfirmed source. We find evidence to support the inclusion of 10 of these condidates into the class of CSOs. Thirteen candidates, including the previously unconfirmed source, have been ruled out. Eleven sources require further investigation. The addition of the 10 new confirmed CSOs increases the size of this class of objects by 50%.Comment: 24 pages, incl 8 figures. Accepted for publication in ApJ. Figure quality degraded in the interests of space, full gzipped PS version also available at http://www.ee.nmt.edu/~apeck/papers

Poly(3,4-ethylenedioxythiophene) as a Micro-Neural Interface Material for Electrostimulation

Chronic microstimulation-based devices are being investigated to treat conditions such as blindness, deafness, pain, paralysis, and epilepsy. Small-area electrodes are desired to achieve high selectivity. However, a major trade-off with electrode miniaturization is an increase in impedance and charge density requirements. Thus, the development of novel materials with lower interfacial impedance and enhanced charge storage capacity is essential for the development of micro-neural interface-based neuroprostheses. In this report, we study the use of conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) as a neural interface material for microstimulation of small-area iridium electrodes on silicon-substrate arrays. Characterized by electrochemical impedance spectroscopy, electrodeposition of PEDOT results in lower interfacial impedance at physiologically relevant frequencies, with the 1 kHz impedance magnitude being 23.3 ± 0.7 kΩ, compared to 113.6 ± 3.5 kΩ for iridium oxide (IrOx) on 177 μm2 sites. Further, PEDOT exhibits enhanced charge storage capacity at 75.6 ± 5.4 mC/cm2 compared to 28.8 ± 0.3 mC/cm2 for IrOx, characterized by cyclic voltammetry (50 mV/s). These improvements at the electrode interface were corroborated by observation of the voltage excursions that result from constant current pulsing. The PEDOT coatings provide both a lower amplitude voltage and a more ohmic representation of the applied current compared to IrOx. During repetitive pulsing, PEDOT-coated electrodes show stable performance and little change in electrical properties, even at relatively high current densities which cause IrOx instability. These findings support the potential of PEDOT coatings as a micro-neural interface material for electrostimulation