A broad spectrum neutron spectrometer utilizing a high energy Bonner sphere extension

A novel broad spectrum neutron spectrometer has been created to extend the useful energy range of existing neutron Bonner Sphere Spectrometers (BSS). Both an active LiI(Eu) scintillator probe and passive gold foil detector were utilized to extend the energy response of the existing BSS. Above 20 MeV the energy structure for the standard polyethylene BSS are poor because the response functions are not unique. MCNPX was used to investigate several modifications to the BSS system which resulted in the Bonner Sphere Extension (BSE). This cost effective extension uses several concentric spheres of copper, lead, and tungsten heavy metal downscatter materials to extend the useful range of the current BSS from 20 MeV to above 1 GeV. Using both a 3" and 5" inner polyethylene spheres, aluminum shell sets were made with a 1" cavity and filled with the high Z materials for six total sets of spheres. a 12" and 8" polyethylene sphere were also milled to accept the heavy metal spheres. The system was validated at the Los Alamos Neutron Science Center (LANSCE) neutron beam. The system was calibrated at LANSCE for neutrons up to 800 MeV on target 4's 15 degree right flightpath (4FP15R) at 90 meters. Detailed models in MCNPX were made of the BSS, BSE and LANSCE facilities. Fine group responses were made and compared to the unfolded data from LANSCE. A vast improvement over the BSS system alone was seen with reasonable agreement with time of flight data measured at LANSCE and MCNPX calculated neutron spectra.M.S.Committee Chair: Hertel, Nolan; Committee Co-Chair: Howell, Rebecca; Committee Member: Wang, Chris C-

Update on INSIGHTS Development

INSIGHTS is a transformational separate effects testing capability to perform in situ irradiation studies and characterization of the microscale behavior of nuclear fuel materials under a wide variety of in-pile conditions. Separate effects testing including growth, irradiation, and monitoring of these materials, and encompasses the full science based approach for fuels development from the nanoscale to the mesoscale behavior of the sample material and other defects driven by the modeling and simulation efforts of INL

The First High Redshift Quasar from Pan-STARRS

We present the discovery of the first high redshift (z > 5.7) quasar from the Panoramic Survey Telescope and Rapid Response System 1 (Pan-STARRS1 or PS1). This quasar was initially detected as an i dropoutout in PS1, confirmed photometrically with the SAO Widefield InfraRed Camera (SWIRC) at Arizona's Multiple Mirror Telescope (MMT) and the Gamma-Ray Burst Optical/Near-Infrared Detector (GROND) at the MPG 2.2 m telescope in La Silla. The quasar was verified spectroscopically with the the MMT Spectrograph, Red Channel and the Cassegrain Twin Spectrograph (TWIN) at the Calar Alto 3.5 m telescope. It has a redshift of 5.73, an AB z magnitude of 19.4, a luminosity of 3.8 x 10^47 erg/s and a black hole mass of 6.9 x 10^9 solar masses. It is a Broad Absorption Line quasar with a prominent Ly-beta peak and a very blue continuum spectrum. This quasar is the first result from the PS1 high redshift quasar search that is projected to discover more than a hundred i dropout quasars, and could potentially find more than 10 z dropout (z > 6.8) quasars.Comment: 8 pages, 7 figure

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1

Background: Very little is known about the immunodominance patterns of HIV-1-specific T cell responses during primary HIV-1 infection and the reasons for human lymphocyte antigen (HLA) modulation of disease progression. Methods and Findings: In a cohort of 104 individuals with primary HIV-1 infection, we demonstrate that a subset of CD8+ T cell epitopes within HIV-1 are consistently targeted early after infection, while other epitopes subsequently targeted through the same HLA class I alleles are rarely recognized. Certain HLA alleles consistently contributed more than others to the total virus-specific CD8+ T cell response during primary infection, and also reduced the absolute magnitude of responses restricted by other alleles if coexpressed in the same individual, consistent with immunodomination. Furthermore, individual HLA class I alleles that have been associated with slower HIV-1 disease progression contributed strongly to the total HIV-1-specific CD8+ T cell response during primary infection. Conclusions: These data demonstrate consistent immunodominance patterns of HIV-1-specific CD8+ T cell responses during primary infection and provide a mechanistic explanation for the protective effect of specific HLA class I alleles on HIV-1 disease progression

Observational and Dynamical Characterization of Main-Belt Comet P/2010 R2 (La Sagra)

We present observations of comet-like main-belt object P/2010 R2 (La Sagra) obtained by Pan-STARRS 1 and the Faulkes Telescope-North on Haleakala in Hawaii, the University of Hawaii 2.2 m, Gemini-North, and Keck I telescopes on Mauna Kea, the Danish 1.54 m telescope at La Silla, and the Isaac Newton Telescope on La Palma. An antisolar dust tail is observed from August 2010 through February 2011, while a dust trail aligned with the object's orbit plane is also observed from December 2010 through August 2011. Assuming typical phase darkening behavior, P/La Sagra is seen to increase in brightness by >1 mag between August 2010 and December 2010, suggesting that dust production is ongoing over this period. These results strongly suggest that the observed activity is cometary in nature (i.e., driven by the sublimation of volatile material), and that P/La Sagra is therefore the most recent main-belt comet to be discovered. We find an approximate absolute magnitude for the nucleus of H_R=17.9+/-0.2 mag, corresponding to a nucleus radius of ~0.7 km, assuming an albedo of p=0.05. Using optical spectroscopy, we find no evidence of sublimation products (i.e., gas emission), finding an upper limit CN production rate of Q_CN<6x10^23 mol/s, from which we infer an H2O production rate of Q_H2O<10^26 mol/s. Numerical simulations indicate that P/La Sagra is dynamically stable for >100 Myr, suggesting that it is likely native to its current location and that its composition is likely representative of other objects in the same region of the main belt, though the relatively close proximity of the 13:6 mean-motion resonance with Jupiter and the (3,-2,-1) three-body mean-motion resonance with Jupiter and Saturn mean that dynamical instability on larger timescales cannot be ruled out.Comment: 23 pages, 13 figures, accepted for publication in A

Lacerta I and Cassiopeia III. Two Luminous and Distant Andromeda Satellite Dwarf Galaxies Found in the 3π Pan-STARRS1 Survey

We report the discovery of two new dwarf galaxies, Lacerta I/Andromeda XXXI (Lac I/And XXXI) and Cassiopeia III/Andromeda XXXII (Cas III/And XXXII), in stacked Pan-STARRS1 r P1- and i P1-band imaging data. Both are luminous systems (MV ~ –12) located at projected distances of 20fdg3 and 10fdg5 from M31. Lac I and Cas III are likely satellites of the Andromeda galaxy with heliocentric distances of $756^{+44}_{-28}{\rm \,kpc}$ and $772^{+61}_{-56}{\rm \,kpc}$, respectively, and corresponding M31-centric distances of 275 ± 7 kpc and $144^{+6}_{-4}{\rm \,kpc}$. The brightest of recent Local Group member discoveries, these two new dwarf galaxies owe their late discovery to their large sizes ($r_h = 4.2^{+0.4}_{-0.5}$ arcmin or $912^{+124}_{-93}{\rm \,pc}$ for Lac I; $r_h = 6.5^{+1.2}_{-1.0}$ arcmin or 1456 ± 267 pc for Cas III) and consequently low surface brightness (μ0 ~ 26.0 mag arcsec–2), as well as to the lack of a systematic survey of regions at large radii from M31, close to the Galactic plane. This latter limitation is now alleviated by the 3π Pan-STARRS1 survey, which could lead to the discovery of other distant Andromeda satellite dwarf galaxies.Astronom

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1

BACKGROUND: Very little is known about the immunodominance patterns of HIV-1-specific T cell responses during primary HIV-1 infection and the reasons for human lymphocyte antigen (HLA) modulation of disease progression. METHODS AND FINDINGS: In a cohort of 104 individuals with primary HIV-1 infection, we demonstrate that a subset of CD8(+) T cell epitopes within HIV-1 are consistently targeted early after infection, while other epitopes subsequently targeted through the same HLA class I alleles are rarely recognized. Certain HLA alleles consistently contributed more than others to the total virus-specific CD8(+) T cell response during primary infection, and also reduced the absolute magnitude of responses restricted by other alleles if coexpressed in the same individual, consistent with immunodomination. Furthermore, individual HLA class I alleles that have been associated with slower HIV-1 disease progression contributed strongly to the total HIV-1-specific CD8(+) T cell response during primary infection. CONCLUSIONS: These data demonstrate consistent immunodominance patterns of HIV-1-specific CD8(+) T cell responses during primary infection and provide a mechanistic explanation for the protective effect of specific HLA class I alleles on HIV-1 disease progression