Long-Lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

<div><p>In central Nigeria <i>Anopheles</i> mosquitoes transmit malaria and lymphatic filariasis (LF). The strategy used for interrupting LF transmission in this area is annual mass drug administration (MDA) with albendazole and ivermectin, but after 8 years of MDA, entomological evaluations in sentinel villages showed continued low-grade mosquito infection rates of 0.32%. After long-lasting insecticidal net (LLIN) distribution by the national malaria program in late 2010, however, we were no longer able to detect infected vectors over a 24-month period. This is evidence that LLINs are synergistic with MDA in interrupting LF transmission.</p></div

13 years of mass drug administration for LF in Plateau and Nasarawa states, Nigeria, 2000–2012 (n = 36,119,921).

<p>13 years of mass drug administration for LF in Plateau and Nasarawa states, Nigeria, 2000–2012 (n = 36,119,921).</p

Mosquito lymphatic filariasis infection rates (all larval stages) in Plateau and Nasarawa state sentinel sites.

<p>Mosquito lymphatic filariasis infection rates (all larval stages) in Plateau and Nasarawa state sentinel sites.</p