76 research outputs found

    “We’re Still Here … We’re Not Giving Up”: Black and Latino Men’s Narratives of Transition to Community College

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    Objective: This study examines masculinity in a manner commensurate with established feminist frameworks to deconstruct a patriarchal system that ill-serves both men and women. Method: We utilized standpoint theory and narrative analysis to examine longitudinal, qualitative data from first-year Black and Latino males as they transition into community college through their second semester. Findings: Positionality is critical to understanding the success of Black and Latino males and their response to institutional structures. In many instances, men leveraged normative constructions of masculinity as aids to their success, and their resilience and confidence were filtered through their perceived development into adults. Conclusion: Implications for practice include the creation of spaces for men to talk about what it means to be a man in college and ways to influence men to make the most of resources when proffered, even if they tend to avoid seeking them out on their own. Further research should seek to understand how men develop and evolve their concepts of masculinity as well as how and to what extent spaces for men actually work to dismantle hegemonic masculinity

    “We’re Still Here … We’re Not Giving Up”: Black and Latino Men’s Narratives of Transition to Community College

    Get PDF
    Objective: This study examines masculinity in a manner commensurate with established feminist frameworks to deconstruct a patriarchal system that ill-serves both men and women. Method: We utilized standpoint theory and narrative analysis to examine longitudinal, qualitative data from first-year Black and Latino males as they transition into community college through their second semester. Findings: Positionality is critical to understanding the success of Black and Latino males and their response to institutional structures. In many instances, men leveraged normative constructions of masculinity as aids to their success, and their resilience and confidence were filtered through their perceived development into adults. Conclusion: Implications for practice include the creation of spaces for men to talk about what it means to be a man in college and ways to influence men to make the most of resources when proffered, even if they tend to avoid seeking them out on their own. Further research should seek to understand how men develop and evolve their concepts of masculinity as well as how and to what extent spaces for men actually work to dismantle hegemonic masculinity

    Identification and Characterization of Novel Perivascular Adventitial Cells in the Whole Mount Mesenteric Branch Artery Using Immunofluorescent Staining and Scanning Confocal Microscopy Imaging

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    A novel perivascular adventitial cell termed, adventitial neuronal somata (ANNIES) expressing the neural cell adhesion molecule (NCAM) and the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP), exists in the adult rat mesenteric branch artery (MBA) in situ. In addition, we have previously shown that ANNIES coexpress CGRP and NCAM. We now show that ANNIES express the neurite growth marker, growth associated protein-43(Gap-43), palladin, and the calcium sensing receptor (CaSR), that senses changes in extracellular Ca(2+) and participates in vasodilator mechanisms. Thus, a previously characterized vasodilator, calcium sensing autocrine/paracrine system, exists in the perivascular adventitia associated with neural-vascular interface. Images of the whole mount MBA segments were analyzed under scanning confocal microscopy. Confocal analysis showed that the Gap-43, CaSR, and palladin were present in ANNIES about 37 ± 4%, 94 ± 6%, and 80 ± 10% respectively, comparable to CGRP (100%). Immunoblots from MBA confirmed the presence of Gap-43 (48 kD), NCAM (120 and 140 kD), and palladin (90–92 and 140 kD). In summary, CGRP, and NCAM-containing neural cells in the perivascular adventitia also express palladin and CaSR, and coexpress Gap-43 which may participate in response to stress/injury and vasodilator mechanisms as part of a perivascular sensory neural network

    Community College Student Engagement Patterns: A Typology Revealed Through Exploratory Cluster Analysis

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    This study employs survey data from the Center for Community College Student Engagement to examine the similarities and differences that exist across student-level domains in terms of student engagement in community colleges. In total, the sample used in the analysis pools data from 663 community colleges and includes more than 320,000 students. Using data-mining techniques to discover a parsimonious number of natural clusters and, in turn, a k-means cluster analysis as a means of revealing a naturally occurring typology of engagement patterns, our findings reveal that support service utilization is the most distinguishing feature of the similarities and dissimilarities across student groups, suggesting areas for further theory development and testing

    Community College Student Engagement Patterns: A Typology Revealed Through Exploratory Cluster Analysis

    Get PDF
    This study employs survey data from the Center for Community College Student Engagement to examine the similarities and differences that exist across student-level domains in terms of student engagement in community colleges. In total, the sample used in the analysis pools data from 663 community colleges and includes more than 320,000 students. Using data-mining techniques to discover a parsimonious number of natural clusters and, in turn, a k-means cluster analysis as a means of revealing a naturally occurring typology of engagement patterns, our findings reveal that support service utilization is the most distinguishing feature of the similarities and dissimilarities across student groups, suggesting areas for further theory development and testing

    Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

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    BACKGROUND: Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes. METHODS: We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization. RESULTS: During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events. CONCLUSIONS: Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)

    Modulation of resistance artery force generation by extracellular Ca2+

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