Synthesis, In vitro Antifungal and Antitumour Activity of Some Triorganotin(IV) N,C,N-Chelates

The in vitro antifungal activity of compounds 1-3 ( { [ ( CH 3 ) 2 NCH 2 ] 2 C 6 H 3 } R 2 SnX ; (where X=Cl, R=n-Bu for 1, X=Br, R=n-Bu for 2 and x= PF 6 , R=n=Bu for 3)) was estimated with the help of a modified microdilution format of the M27-A guidelines and was compared with in vitro activity of their diphenyltin(IV) analogues 4 and 5 (where X=Br, R=Ph for 4 and X= PF 6 , R=Ph for 5), and of drugs currently in clinical use (ketoconazole, fluconazole and amphotericin B). It was found that in coordinating solvents the more soluble derivative 2 is less active than the phenyl one (4), and compounds 1 and 3 are even inactive

Behavioristické modely ve veřejném sektoru

In this article, we are concerned with an issue of a behavioral models of the firm and their application on the public sector. In the opening chapter, behavioral models of the firm are briefly dealt with (Simon's model, Model of Cyert and March, Doyle's model), later we concentrate on the application of these models on the public sector, espacially on the University