High contrast Mach-Zehnder lithium atom interferometer in the Bragg regime

We have constructed an atom interferometer of the Mach-Zehnder type, operating with a supersonic beam of lithium. Atom diffraction uses Bragg diffraction on laser standing waves. With first order diffraction, our apparatus has given a large signal and a very good fringe contrast (74%), which we believe to be the highest ever observed with atom interferometers. This apparatus will be applied to high sensitivity measurementsComment: 6 pages, 3 figures, accepted by Appl. Phys.

Instantaneous Normal Mode analysis of liquid HF

We present an Instantaneous Normal Modes analysis of liquid HF aimed to clarify the origin of peculiar dynamical properties which are supposed to stem from the arrangement of molecules in linear hydrogen-bonded network. The present study shows that this approach is an unique tool for the understanding of the spectral features revealed in the analysis of both single molecule and collective quantities. For the system under investigation we demonstrate the relevance of hydrogen-bonding ``stretching'' and fast librational motion in the interpretation of these features.Comment: REVTeX, 7 pages, 5 eps figures included. Minor changes in the text and in a figure. Accepted for publication in Phys. Rev. Let

The effect of induced forelimb lameness on thoracolumbar kinematics during treadmill locomotion

Reasons for performing study: Lameness has often been suggested to result in altered movement of the back, but there are no detailed studies describing such a relationship in quantitative terms. Objectives: To quantify the effect of induced subtle forelimb lameness on thoracolumbar kinematics in the horse. Methods: Kinematics of 6 riding horses was measured at walk and at trot on a treadmill before and after the induction of reversible forelimb lameness grade 2 (AAEP scale 1-5). Ground reaction forces (GRF) for individual limbs were calculated from kinematics. Results: The horses significantly unloaded the painful limb by 11.5% at trot, while unloading at walk was not significant. The overall flexion-extension range of back motion decreased on average by 0.2° at walk and increased by 3.3° at trot (P<0.05). Changes in angular motion patterns of vertebral joints were noted only at trot, with an increase in flexion of 0.9° at T10 (i.e. angle between T6, T10 and T13) during the stance phase of the sound diagonal and an increase in extension of the thoracolumbar area during stance of the lame diagonal (0.7° at T13, 0.8° at T17, 0.5° at L1, 0.4° at L3 and 0.3° at L5) (P<0.05). Lameness further caused a lateral bending of the cranial thoracic vertebral column towards the lame side (1.3° at T10 and 0.9° at T13) (P<0.05) during stance of the lame diagonal. Conclusions: Both range of motion and vertebral angular motion patterns are affected by subtle forelimb lameness. At walk, the effect is minimal, at trot the horses increased the vertebral range of motion and changed the pattern of thoracolumbar motion in the sagittal and horizontal planes, presumably in an attempt to move the centre of gravity away from the lame side and reduce the force on the affected limb. Potential relevance: Subtle forelimb lameness affects thoracolumbar kinematics. Future studies should aim at elucidating whether the altered movement patterns lead to back and/or neck dysfunction in the case of chronic lameness

Phylogeny and gene expression of the complete NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER FAMILY (NPF) in Triticum aestivum L.

NPF genes encode membrane transporters involved in the transport of a large variety of substrates including nitrate and peptides. The NPF gene family has been described for many plants, but the whole NPF gene family for wheat has not been completely identified. The release of the wheat reference genome has enabled the identification of the entire wheat NPF gene family. A systematic analysis of the whole wheat NPF gene family was performed, including responses of specific gene expression to development and nitrogen supply. A total of 331 NPF genes (113 homoeologous groups) have been identified in wheat. The chromosomal location of the NPF genes is unevenly distributed with predominant occurrence in the long arms of the chromosomes. The phylogenetic analysis indicated that wheat NPF genes are closely clustered with Arabidopsis, Brachypodium and rice orthologs, and subdivided into eight subfamilies. The expression profiles of wheat NPF genes were examined using RNA-seq data and identified a subset of 44 NPF genes (homoeologous groups) with contrasting expression responses to nitrogen and/or development in different tissues. The systematic identification of gene composition, chromosomal locations, evolutionary relationships and expression profiles contributes to a better understanding of the roles of the wheat NPF genes and lays the foundation for further functional analysis in wheat

X-ray bolometric corrections for Compton-thick active galactic nuclei

We present X-ray bolometric correction factors, $\kappa_{Bol}$ ($\equiv L_{Bol}/L_X$), for Compton-thick (CT) active galactic nuclei (AGN) with the aim of testing AGN torus models, probing orientation effects, and estimating the bolometric output of the most obscured AGN. We adopt bolometric luminosities, $L_{Bol}$, from literature infrared (IR) torus modeling and compile published intrinsic 2--10 keV X-ray luminosities, $L_{X}$, from X-ray torus modeling of NuSTAR data. Our sample consists of 10 local CT AGN where both of these estimates are available. We test for systematic differences in $\kappa_{Bol}$ values produced when using two widely used IR torus models and two widely used X-ray torus models, finding consistency within the uncertainties. We find that the mean $\kappa_{Bol}$ of our sample in the range $L_{Bol}\approx10^{42}-10^{45}$ erg/s is log$_{10}\kappa_{Bol}=1.44\pm0.12$ with an intrinsic scatter of $\sim0.2$ dex, and that our derived $\kappa_{Bol}$ values are consistent with previously established relationships between $\kappa_{Bol}$ and $L_{Bol}$ and $\kappa_{Bol}$ and Eddington ratio. We investigate if $\kappa_{Bol}$ is dependent on $N_H$ by comparing our results on CT AGN to published results on less-obscured AGN, finding no significant dependence. Since many of our sample are megamaser AGN, known to be viewed edge-on, and furthermore under the assumptions of AGN unification whereby unobscured AGN are viewed face-on, our result implies that the X-ray emitting corona is not strongly anisotropic. Finally, we present $\kappa_{Bol}$ values for CT AGN identified in X-ray surveys as a function of their observed $L_X$, where an estimate of their intrinsic $L_{X}$ is not available, and redshift, useful for estimating the bolometric output of the most obscured AGN across cosmic time.Comment: Accepted for publication in Ap

An Activity Index for Raw Accelerometry Data and Its Comparison with Other Activity Metrics

Accelerometers have been widely deployed in public health studies in recent years. While they collect high-resolution acceleration signals (e.g., 10–100 Hz), research has mainly focused on summarized metrics provided by accelerometers manufactures, such as the activity count (AC) by ActiGraph or Actical. Such measures do not have a publicly available formula, lack a straightforward interpretation, and can vary by software implementation or hardware type. To address these problems, we propose the physical activity index (AI), a new metric for summarizing raw tri-axial accelerometry data. We compared this metric with the AC and another recently proposed metric for raw data, Euclidean Norm Minus One (ENMO), against energy expenditure. The comparison was conducted using data from the Objective Physical Activity and Cardiovascular Health Study, in which 194 women 60–91 years performed 9 lifestyle activities in the laboratory, wearing a tri-axial accelerometer (ActiGraph GT3X+) on the hip set to 30 Hz and an Oxycon portable calorimeter, to record both tri-axial acceleration time series (converted into AI, AC, and ENMO) and oxygen uptake during each activity (converted into metabolic equivalents (METs)) at the same time. Receiver operating characteristic analyses indicated that both AI and ENMO were more sensitive to moderate and vigorous physical activities than AC, while AI was more sensitive to sedentary and light activities than ENMO. AI had the highest coefficients of determination for METs (0.72) and was a better classifier of physical activity intensity than both AC (for all intensity levels) and ENMO (for sedentary and light intensity). The proposed AI provides a novel and transparent way to summarize densely sampled raw accelerometry data, and may serve as an alternative to AC. The AI’s largely improved sensitivity on sedentary and light activities over AC and ENMO further demonstrate its advantage in studies with older adults