5 research outputs found

    A new chemical probe for the detection of the cancer-linked galectin-3

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    A chemical probe was developed for the detection of the emerging cancer marker galectin-3. The probe contains a benzophenone moiety which covalently attaches itself to the protein upon binding and irradiation. Introduction of a fluorescent label via ‘click’ chemistry allows the labelled proteins to be visualized in a gel. With the probe, selective visualization of galectin-3 in protein mixtures was shown and remarkably even in cell lysates

    Kinetics and Mechanisms of Formation and Reactivity of Non-heme Iron Oxygen Intermediates

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