Developing a schedule of replacement part delivery using a computer simulation of aircraft fleet operation

W artykule został opisany proces przygotowania harmonogramu dostaw części zamiennych dla statków powietrznych. W opisanym algorytmie harmonogram dostaw jest opracowany i oceniany przy wykorzystaniu symulacji komputerowej procesu eksploatacji zbioru statków powietrznych. Oprócz przedstawienia głównych punktów algorytmu w publikacji szczegółowo została opisana jedna z metod oceny przygotowanego harmonogramu.This article describes the process of aircraft replacement parts delivery schedule preparation. In the described algorithm the delivery schedule is developed and evaluated using a computer simulated process of operating a set of aircraft. Besides presenting the main features of the algorithm, this publication describes in details one of the methods of schedule evaluation

Management of the procesess of the operations using IT logistic support system

W artykule zostały opisane elementy zarządzania procesami eksploatacyjnymi z wykorzystaniem systemów informatycznych wsparcia eksploatacji statków powietrznych będących na wyposażeniu struktur realizujących i nadzorujących prace serwisowe na przykładzie samolotów F-16 i bezzałogowych statków powietrznych (BSP). W artykule zawarto przykłady wykorzystania systemów opracowanych w Instytucie Technicznym Wojsk Lotniczych, które zawierają cechy charakterystyczne uwzględniające specyfikę eksploatowanych statków powietrznych.The article describes elements of the management of operational processes with the use of IT systems supporting the operation of aircraft taking of F-16's and unmanned aerial vehicles (UAVs) as examples. The systems are used by supervisors performing maintenance work. The article gives examples of systems developed in the Air Force Institute of Technology and include characteristic features and the specifications of operated aircraft

MEMS testing: transition from millions to billions to trillions

pre-printSensors, specifically MEMSbased, have created multiple market tornados over the past 40 years. Most recently there has been a market explosion driven by the widespread adoption of MEMS sensing devices in mobile consumer applications. In the past 5 years the worldwide market has grown from roughly 10 million to 3 billion sensors in mobile devices, representing a growth rate of over 200%/ year. The total market is expected to grow to at least 16 billion sensors in the next 5 years, and a trillion sensors in 10 years

Silicon microsystems for mechatronic applications

While modern microelectronic fabrication processes allow monolithic integration of millions and millions of electronic devices on tiny silicon chips and thus form a technological base for implementation of high-performance electronic systems, they are also capable of realizing sensing and actuating functions. Although this may require some minor changes in standard processing and thus increase the fabrication costs, the unique combination of sensors, actuators, and electronic circuits can provide implementation of miniature microsystems featuring unprecedented functionality. Their principles, potentials, and applications in mechatronic systems are the central topic of this contribution

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia

The genome of Tannerella forsythia, an etiologic factor of chronic periodontitis, contains several genes encoding putative proteases. Here, we characterized a subtilisin-like serine protease of T. forsythia referred to as mirolase. Recombinant full-length latent promirolase (85 kDa, without its signal peptide) processed itself through sequential autoproteolytic cleavages into a mature enzyme of 40 kDa. Mirolase latency was driven by the N-terminal prodomain (NTP). In stark contrast to almost all known subtilases, the cleaved NTP remained non-covalently associated with mirolase, inhibiting its proteolytic, but not amidolytic, activity. Full activity was observed only after the NTP was gradually, and fully, degraded. Both activity and processing was absolutely dependent on calcium ions, which were also essential for enzyme stability. As a consequence, both serine protease inhibitors and calcium ions chelators inhibited mirolase activity. Activity assays using an array of chromogenic substrates revealed that mirolase specificity is driven not only by the substrate-binding subsite S1, but also by other subsites. Taken together mirolase is a calcium-dependent serine protease of the S8 family with the unique mechanism of activation that may contribute to T. forsythia pathogenicity by degradation of fibrinogen, hemoglobin and the antimicrobial peptide LL-37