A Balance of Interests: the Concordance of Copyright Law and Moral Rights in the Worldwide Economy

LECTURE IN INTERNAL MEDICINE PROPAEDEUTIC

EHRA classes, additional cardiovascular risk and quality of life in patients during the first six months of atrial flutter and atrial fibrillation radiofrequency

, Abstract The aim of our study was to evaluate EHRA, additional cardiovascular risk (ACVR) classes and quality of life in patients during the first six months of radiofrequency ablation (RFA) of atrial fibrillation and flutter (AF, AFl). Materials and methods. 96 patients (54 men and 42 women) at the age of 59 ± 9 years who underwent RFA of AF and AFl were examined. The European Heart Rhythm Association (EHRA) classes on the arrhythmias symptoms score, ACVR classes and indicators of physical and mental health (PH and MH) components by the SF-36 questionnaire in the groups of AF, AFl and combined AF/AFl were evaluated before RFA, in the early postoperative period (on the 3–7 day) and 6 months after the procedure. Standard statistical procedures were performed for data processing using Microsoft Excel. Results. An increase in the frequency of the EHRA classes I and II at 6 months after RFA performing was observed the most in the isolated arrhythmia groups and less frequently in the context of a AF/ AFl combination. The ACVR classes 1 and 2 were observed more often by the 6 month after RFA, but only in the AF and AFl groups. In AF and AFl groups both PH and MH were increased in the postoperative period and six months after RFA, in the AF/AFl group - were increased in the early postoperative period, decreased by the 6 month not reaching the baseline values. MH across all three groups increased in the early postoperative period, remained unchanged up to the sixth month in the AF group, continued to increase in the AFl group, but decreased in the AF/AFl group altogether. Conclusions. The symptoms severity did not exceed the EHRA class I 6 months after RFA of AFl in most patients, after RFA of AF was by one third less frequently, and after RFA of combined AF/AFl was only in half of the patients. Decline of the ACVR levels 6 months after RFA was observed only in isolated AF and AFl groups. Quality of life PH and MH indicators increased in the early postoperative period after RFA in all patients, after 6 months - only in the isolated AFl group, decreasing in the combined AF/AFl group

QTC INTERVAL DURATION CLASS AND DRUG THERAPY OF PATIENCE IN A FIRST YEAR AFTER PACEMAKER IMPLANTATION

49 patients (28 female, 21 male) with implanted DDD/DDDR, VVI/VVIR and CRT pacemakers are investigated. Purpose frequency and dose rate of anticoagulants, antiplatelet agents, direct thrombin inhibitors, cardiac glycosides, amiodarone; ivabradine, diuretics, aldosterone antagonists, beta-adrenergic blockers, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), statins were evaluated before, in acute postoperative period (3–5 days), 6 months and 1 year after pacemaker implantation. Patients were divided into classes 1 (normal QTc (320–440 ms)) – 24 (49 %) patients) and 2 (long QTc (> 440 msec)) – 25 (51 %) patients) of QTc interval duration. To process the data using standard statistical procedures using Microsoft Excel. It was more often prescriptions of new anticoagulants, beta-adrenergic blockers, ARBs, statins to patients in the first year after pacemaker implantation. QTc interval duration lengthening was associated with a greater purpose frequency and doses of amiodarone, diuretics, beta-adrenergic blockers, ACE inhibitors, ARBs and statins. Patients with implanted pacemaker need individualized drug therapy according to QTc interval duration, in particular, enhancing antiischemic, antihypertensive, antiarrhythmic therapy and therapy of chronic heart failure in patients with QTc interval duration lengthening

FUNCTIONAL CLASSES AND CLINICAL CHARACTERISTICS OF CHRONIC HEART FAILURE IN PATIENTS WITH ATRIAL FIBRILLATION AND/OR FLUTTER AFTER RADIOFREQUENCY ABLATION

The combination of atrial fibrillation and/or flutter and chronic heart failure is a frequent problem for many patients. Radiofrequency ablation is effective in the strategy for controlling the rhythm of patients with atrial fibrillation and/or flutter, but always requires concomitant therapeutic support. The study involved 70 patients with atrial fibrillation and/or flutter after radiofrequency ablation which were divided into groups according to the functional class of chronic heart failure. Gender and age of patients; types of ischemic heart disease; stages of chronic heart failure; degrees of arterial hypertension; the form of atrial fibrillation and flutter; class EHRA; the presence of diabetes mellitus type 1 or 2 we evaluated. The female sex prevailed in the group of II functional class of chronic heart failure than in I functional class or III functional class. Ischemic heart disease, first of all angina of effort, in patients with III functional class of chronic heart failure was significantly more frequent. In group of III functional class of chronic heart failure there were significantly more patients with 3 degrees of arterial hypertension. Male patients, regardless of functional class of chronic heart failure, more often than females are conducted invasive methods of treatment for atrial fibrillation/flutter. With increasing of functional class of angina the functional class of chronic heart failure is increasing. Among patients II and III functional class of chronic heart failure prevails the arterial hypertension III degree, which may be a predictor of adverse prognosis

Heart arrhythmias

LECTURE IN INTERNAL MEDICINE FOR V COURSE STUDENT

Pneumonia

LECTURE IN INTERNAL MEDICINE FOR IV COURSE STUDENT

Essentials of Diagnosis, Treatment and Prevention of Major Endocrine Diseases: Diabetes Mellitus

LECTURE IN INTERNAL MEDICINE FOR IV COURSE STUDENT

Myocarditis and Cardiomyopathies

LECTURE IN INTERNAL MEDICINE FOR V COURSE STUDENT

Signs and symptoms of cardiovascular system diseases (syndrome of acute and chronic coronary insufficiency)

LECTURE IN INTERNAL MEDICINE PROPAEDEUTIC

Signs and symptoms of cardiovascular system diseases (syndrome of heart failure)

LECTURE IN INTERNAL MEDICINE PROPAEDEUTIC