Musculoskeletal injuries in Us air Force Security Forces, January 2009 to December 2018

OBJECTIVE: to determine the incidence, types, and risk factors of musculoskeletal injuries in a military security forces population. METHODS: Demographic and diagnostic data were retrieved on enlisted US Air Force security forces personnel who served on active duty between January 2009 and December 2018. Incidence rates and ratios were calculated using Poisson regression. RESULTS: During 251,787 person-years of exposure, 62,489 personnel served on active duty. Of these, 40,771 (65.2%) were diagnosed with at least one musculoskeletal injury. The majority (60.1%) of the 164,078 unique musculoskeletal injuries were inflammation and pain secondary to overuse. After adjusting for other factors, women had a 31% higher injury rate than men, and those who were overweight and obese had 15% and 30% higher rates, respectively, than normal-weight peers. CONCLUSIONS: Modifiable and non-modifiable factors contribute to musculoskeletal injuries in the security forces career field

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Deregulated extracellular signal-regulated kinase (ERK) signaling drives cancer growth. Normally, ERK activity is self-limiting by the rapid inactivation of upstream kinases and delayed induction of dual-specificity MAP kinase phosphatases (MKPs/DUSPs). However, interactions between these feedback mechanisms are unclear. Here we show that, although the MKP DUSP5 both inactivates and anchors ERK in the nucleus, it paradoxically increases and prolongs cytoplasmic ERK activity. The latter effect is caused, at least in part, by the relief of ERK-mediated RAF inhibition. The importance of this spatiotemporal interaction between these distinct feedback mechanisms is illustrated by the fact that expression of oncogenic BRAF(V600E), a feedback-insensitive mutant RAF kinase, reprograms DUSP5 into a cell-wide ERK inhibitor that facilitates cell proliferation and transformation. In contrast, DUSP5 deletion causes BRAF(V600E)-induced ERK hyperactivation and cellular senescence. Thus, feedback interactions within the ERK pathway can regulate cell proliferation and transformation, and suggest oncogene-specific roles for DUSP5 in controlling ERK signaling and cell fate

Star formation concentration as a tracer of environmental quenching in action: a study of the Eagle and C-Eagle simulations

We study environmental quenching in the Eagle}/C-Eagle cosmological hydrodynamic simulations over the last 11 Gyr (i.e. $z=0-2$). The simulations are compared with observations from the SAMI Galaxy Survey at $z=0$. We focus on satellite galaxies in galaxy groups and clusters ($10^{12}\,\rm M_{\odot}$ $\lesssim$ $M_{200}$ < $3 \times 10^{15}\, \rm M_{\odot}$). A star-formation concentration index [$C$-index $= \log_{10}(r_\mathrm{50,SFR} / r_\mathrm{50,rband})$] is defined, which measures how concentrated star formation is relative to the stellar distribution. Both Eagle/C-Eagle and SAMI show a higher fraction of galaxies with low $C$-index in denser environments at $z=0-0.5$. Low $C$-index galaxies are found below the SFR-$M_{\star}$ main sequence (MS), and display a declining specific star formation rate (sSFR) with increasing radii, consistent with ``outside-in'' environmental quenching. Additionally, we show that $C$-index can be used as a proxy for how long galaxies have been satellites. These trends become weaker at increasing redshift and are absent by $z=1-2$. We define a quenching timescale $t_{\rm quench}$ as how long it takes satellites to transition from the MS to the quenched population. We find that simulated galaxies experiencing ``outside-in'' environmental quenching at low redshift ($z=0\sim0.5$) have a long quenching timescale (median $t_{\rm quench}$ > 2 Gyr). The simulated galaxies at higher redshift ($z=0.7\sim2$) experience faster quenching (median $t_{\rm quench}$ < 2Gyr). At $z\gtrsim 1-2$ galaxies undergoing environmental quenching have decreased sSFR across the entire galaxy with no ``outside-in'' quenching signatures and a narrow range of $C$-index, showing that on average environmental quenching acts differently than at $z\lesssim 1$.Comment: 21 pages, 17 figures

The SAMI Galaxy Survey: Shocks and Outflows in a normal star-forming galaxy

We demonstrate the feasibility and potential of using large integral field spectroscopic surveys to investigate the prevalence of galactic-scale outflows in the local Universe. Using integral field data from SAMI and the Wide Field Spectrograph, we study the nature of an isolated disk galaxy, SDSS J090005.05+000446.7 (z = 0.05386). In the integral field datasets, the galaxy presents skewed line profiles changing with position in the galaxy. The skewed line profiles are caused by different kinematic components overlapping in the line-of-sight direction. We perform spectral decomposition to separate the line profiles in each spatial pixel as combinations of (1) a narrow kinematic component consistent with HII regions, (2) a broad kinematic component consistent with shock excitation, and (3) an intermediate component consistent with shock excitation and photoionisation mixing. The three kinematic components have distinctly different velocity fields, velocity dispersions, line ratios, and electron densities. We model the line ratios, velocity dispersions, and electron densities with our MAPPINGS IV shock and photoionisation models, and we reach remarkable agreement between the data and the models. The models demonstrate that the different emission line properties are caused by major galactic outflows that introduce shock excitation in addition to photoionisation by star-forming activities. Interstellar shocks embedded in the outflows shock-excite and compress the gas, causing the elevated line ratios, velocity dispersions, and electron densities observed in the broad kinematic component. We argue from energy considerations that, with the lack of a powerful active galactic nucleus, the outflows are likely to be driven by starburst activities. Our results set a benchmark of the type of analysis that can be achieved by the SAMI Galaxy Survey on large numbers of galaxies.Comment: 17 pages, 15 figures. Accepted to MNRAS. References update

The SAMI Galaxy Survey: energy sources of the turbulent velocity dispersion in spatially-resolved local star-forming galaxies

We investigate the energy sources of random turbulent motions of ionised gas from H$\alpha$ emission in eight local star-forming galaxies from the Sydney-AAO Multi-object Integral field spectrograph (SAMI) Galaxy Survey. These galaxies satisfy strict pure star-forming selection criteria to avoid contamination from active galactic nuclei (AGN) or strong shocks/outflows. Using the relatively high spatial and spectral resolution of SAMI, we find that -- on sub-kpc scales our galaxies display a flat distribution of ionised gas velocity dispersion as a function of star formation rate (SFR) surface density. A major fraction of our SAMI galaxies shows higher velocity dispersion than predictions by feedback-driven models, especially at the low SFR surface density end. Our results suggest that additional sources beyond star formation feedback contribute to driving random motions of the interstellar medium (ISM) in star-forming galaxies. We speculate that gravity, galactic shear, and/or magnetorotational instability (MRI) may be additional driving sources of turbulence in these galaxies.Comment: 11 pages, 5 figures, 3 tables. Accepted by MNRA

The SAMI Galaxy Survey: Global stellar populations on the size-mass plane

We present an analysis of the global stellar populations of galaxies in the SAMI Galaxy Survey. Our sample consists of 1319 galaxies spanning four orders of magnitude in stellar mass and includes all morphologies and environments. We derive luminosity-weighted, single stellar population equivalent stellar ages, metallicities and alpha enhancements from spectra integrated within one effective radius apertures. Variations in galaxy size explain the majority of the scatter in the age--mass and metallicity--mass relations. Stellar populations vary systematically in the plane of galaxy size and stellar mass, such that galaxies with high stellar surface mass density are older, more metal-rich and alpha-enhanced than less dense galaxies. Galaxies with high surface mass densities have a very narrow range of metallicities, however, at fixed mass, the spread in metallicity increases substantially with increasing galaxy size (decreasing density). We identify residual correlations with morphology and environment. At fixed mass and size, galaxies with late-type morphologies, small bulges and low Sersic n are younger than early-type, high n, high bulge-to-total galaxies. Age and metallicity both show small residual correlations with environment; at fixed mass and size, galaxies in denser environments or more massive halos are older and somewhat more metal rich than those in less dense environments. We connect these trends to evolutionary tracks within the size--mass plane.Comment: 25 pages, 18 figures, MNRAS in press Corrected typo in author lis

The SAMI–Fornax Dwarfs Survey – III. Evolution of [α/Fe] in dwarfs, from Galaxy Clusters to the Local Group

Using very deep, high spectral resolution data from the SAMI Integral Field Spectrograph, we study the stellar population properties of a sample of dwarf galaxies in the Fornax Cluster, down to a stellar mass of 107 M☉, which has never been done outside the Local Group. We use full spectral fitting to obtain stellar population parameters. Adding massive galaxies from the ATLAS3D project, which we re-analysed, and the satellite galaxies of the Milky Way, we obtained a galaxy sample that covers the stellar mass range 104–1012 M☉. Using this large range, we find that the mass–metallicity relation is not linear. We also find that the [α/Fe]-stellar mass relation of the full sample shows a U-shape, with a minimum in [α/Fe] for masses between 109 and 1010 M☉. The relation between [α/Fe] and stellar mass can be understood in the following way: when the faintest galaxies enter the cluster environment, a rapid burst of star formation is induced, after which the gas content is blown away by various quenching mechanisms. This fast star formation causes high [α/Fe] values, like in the Galactic halo. More massive galaxies will manage to keep their gas longer and form several bursts of star formation, with lower [α/Fe] as a result. For massive galaxies, stellar populations are regulated by internal processes, leading to [α/Fe] increasing with mass. We confirm this model by showing that [α/Fe] correlates with clustercentric distance in three nearby clusters and also in the halo of the Milky Way.</p

The SAMI Galaxy Survey: A Range in S0 Properties Indicating Multiple Formation Pathways

It has been proposed that S0 galaxies are either fading spirals or the result of galaxy mergers. The relative contribution of each pathway, and the environments in which they occur remains unknown. Here we investigate stellar and gas kinematics of 219 S0s in the SAMI Survey to look for signs of multiple formation pathways occurring across the full range of environments. We identify a large range of rotational support in their stellar kinematics, which correspond to ranges in their physical structure. We find that pressure-supported S0s with $v/{\sigma}$ below 0.5 tend to be more compact and feature misaligned stellar and gas components, suggesting an external origin for their gas. We postulate that these S0s are consistent with being formed through a merger process. Meanwhile, comparisons of ellipticity, stellar mass and S\'ersic index distributions with spiral galaxies shows that the rotationally supported S0s with $v/{\sigma}$ above 0.5 are more consistent with a faded spiral origin. In addition, a simulated merger pathway involving a compact elliptical and gas-rich satellite results in an S0 that lies within the pressure-supported group. We conclude that two S0 formation pathways are active, with mergers dominating in isolated galaxies and small groups, and the faded spiral pathway being most prominent in large groups ($10^{13} < M_{halo} < 10^{14}$).Comment: 14 pages, 12 figures, accepted for publication in MNRA