8,175 research outputs found

    Relationship-based practice revisited [editorial]

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    Editorial to Special Issue. This editorial introduces a special issue of the Journal of Social Work Practice called 'Relationship-based Practice Revisited'

    Simplified SIMPs and the LHC

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    The existence of Dark Matter (DM) in the form of Strongly Interacting Massive Particles (SIMPs) may be motivated by astrophysical observations that challenge the classical Cold DM scenario. Other observations greatly constrain, but do not completely exclude, the SIMP alternative. The signature of SIMPs at the LHC may consist of neutral, hadron-like, trackless jets produced in pairs. We show that the absence of charged content can provide a very efficient tool to suppress dijet backgrounds at the LHC, thus enhancing the sensitivity to a potential SIMP signal. We illustrate this using a simplified SIMP model and present a detailed feasibility study based on simulations, including a dedicated detector response parametrization. We evaluate the expected sensitivity to various signal scenarios and tentatively consider the exclusion limits on the SIMP elastic cross section with nucleons.Comment: 18 pages, 7 figure

    Metal Cooling in Simulations of Cosmic Structure Formation

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    The addition of metals to any gas can significantly alter its evolution by increasing the rate of radiative cooling. In star-forming environments, enhanced cooling can potentially lead to fragmentation and the formation of low-mass stars, where metal-free gas-clouds have been shown not to fragment. Adding metal cooling to numerical simulations has traditionally required a choice between speed and accuracy. We introduce a method that uses the sophisticated chemical network of the photoionization software, Cloudy, to include radiative cooling from a complete set of metals up to atomic number 30 (Zn) that can be used with large-scale three-dimensional hydrodynamic simulations. Our method is valid over an extremely large temperature range (10 K < T < 10^8 K), up to hydrogen number densities of 10^12 cm^-3. At this density, a sphere of 1 Msun has a radius of roughly 40 AU. We implement our method in the adaptive mesh refinement (AMR) hydrodynamic/N-body code, Enzo. Using cooling rates generated with this method, we study the physical conditions that led to the transition from Population III to Population II star formation. While C, O, Fe, and Si have been previously shown to make the strongest contribution to the cooling in low-metallicity gas, we find that up to 40% of the metal cooling comes from fine-structure emission by S, when solar abundance patterns are present. At metallicities, Z > 10^-4 Zsun, regions of density and temperature exist where gas is both thermally unstable and has a cooling time less than its dynamical time. We identify these doubly unstable regions as the most inducive to fragmentation. At high redshifts, the CMB inhibits efficient cooling at low temperatures and, thus, reduces the size of the doubly unstable regions, making fragmentation more difficult.Comment: 19 pages, 12 figures, significant revision, including new figure

    Numerical Simulations of High Redshift Star Formation in Dwarf Galaxies

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    We present first results from three-dimensional hydrodynamic simulations of the high redshift formation of dwarf galaxies. The simulations use an Eulerian adaptive mesh refinement technique to follow the non-equilibrium chemistry of hydrogen and helium with cosmological initial conditions drawn from a popular Lambda-dominated CDM model. We include the effects of reionization using a uniform radiation field, a phenomenological description of the effect of star formation and, in a separate simulation, the effects of stellar feedback. The results highlight the effects of stellar feedback and photoionization on the baryon content and star formation of galaxies with virial temperatures of approximately 10^4K. Dwarf sized dark matter halos that assemble prior to reionization are able to form stars. Most halos of similar mass that assemble after reionization do not form stars by redshift of three. Dwarf galaxies that form stars show large variations in their gas content because of stellar feedback and photoionization effects. Baryon-to-dark matter mass ratios are found to lie below the cosmic mean as a result of stellar feedback. The supposed substructure problem of CDM is critically assessed on the basis of these results. The star formation histories modulated by radiative and stellar feedbacks are discussed. In addition, metallicities of individual objects are shown to be naturally correlated with their mass-to-light ratios as is also evident in the properties of local dwarf galaxies.Comment: 27 pages, 8 figures, accepted for publication in Ap

    Primary care consultations and costs among HIV-positive individulas in UK primary care 1995-2005: a cohort study

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    Objectives: To investigate the role of primary care in the management of HIV and estimate primary care-associated costs at a time of rising prevalence. Methods: Retrospective cohort study between 1995 and 2005, using data from general practices contributing data to the UK General Practice Research Database. Patterns of consultation and morbidity and associated consultation costs were analysed among all practice-registered patients for whom HIV-positive status was recorded in the general practice record. Results: 348 practices yielded 5504 person-years (py) of follow-up for known HIV-positive patients, who consult in general practice frequently (4.2 consultations/py by men, 5.2 consultations/py by women, in 2005) for a range of conditions. Consultation rates declined in the late 1990s from 5.0 and 7.3 consultations/py in 1995 in men and women, respectively, converging to rates similar to the wider population. Costs of consultation (general practitioner and nurse, combined) reflect these changes, at £100.27 for male patients and £117.08 for female patients in 2005. Approximately one in six medications prescribed in primary care for HIV-positive individuals has the potential for major interaction with antiretroviral medications. Conclusion: HIV-positive individuals known in general practice now consult on a similar scale to the wider population. Further research should be undertaken to explore how primary care can best contribute to improving the health outcomes of this group with chronic illness. Their substantial use of primary care suggests there may be potential to develop effective integrated care pathways
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