Geometric phase and gauge theory structure in quantum computing

We discuss the presence of a geometrical phase in the evolution of a qubit state and its gauge structure. The time evolution operator is found to be the free energy operator, rather than the Hamiltonian operator.Comment: 5 pages, presented at Fifth International Workshop DICE2010: Space-Time-Matter - current issues in quantum mechanics and beyond, Castiglioncello (Tuscany), September 13-17, 201

Drugs and the internet.

Key findings: The number of retailers on the Silk Road increased (from 282 at time 1 to 374 at the last time point), while the number of retailers on the surface web remained relatively stable (92 at time 1 and 101 at the last time point). The increase on the Silk Road is largely driven by international rather than domestic retailers. • On the Silk Road, cannabis and EPS were sold by the largest number of retailers consistently across all time points, followed by MDMA (3,4-methylenedioxy-Nmethylamphetamine) and pharmaceuticals (primarily benzodiazepines and sildenafil). • The type of EPS available from surface web retailers differed substantially from the EPS available from those selling on the Silk Road. EPS sold on the Silk Road more closely mirrored those most commonly used by EDRS participants (i.e. people who regularly use psychostimulants) including drugs from the 2C-x and NBOMe categories, followed by DMT (dimethyltryptamine), Mephedrone and Methylone. • Average prices of methamphetamine, cocaine and ecstasy being sold on the Silk Road remained stable across the time period. Average domestic prices for common quantities of these substances were comparable to prices paid for these same quantities by 2012 EDRS participants. Average international prices for these substances were substantially lower

Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets

<p>Abstract</p> <p>Background</p> <p>Injections of mixtures prepared from crushed tablets contain insoluble particles which can cause embolisms and other complications. Although many particles can be removed by filtration, many injecting drug users do not filter due to availability, cost or performance of filters, and also due to concerns that some of the dose will be lost.</p> <p>Methods</p> <p>Injection solutions were prepared from slow-release morphine tablets (MS Contin^®) replicating methods used by injecting drug users. Contaminating particles were counted by microscopy and morphine content analysed by liquid chromatography before and after filtration.</p> <p>Results</p> <p>Unfiltered tablet extracts contained tens of millions of particles with a range in sizes from < 5 μm to > 400 μm. Cigarette filters removed most of the larger particles (> 50 μm) but the smaller particles remained. Commercial syringe filters (0.45 and 0.22 μm) produced a dramatic reduction in particles but tended to block unless used after a cigarette filter. Morphine was retained by all filters but could be recovered by following the filtration with one or two 1 ml washes. The combined use of a cigarette filter then 0.22 μm filter, with rinses, enabled recovery of 90% of the extracted morphine in a solution which was essentially free of tablet-derived particles.</p> <p>Conclusions</p> <p>Apart from overdose and addiction itself, the harmful consequences of injecting morphine tablets come from the insoluble particles from the tablets and microbial contamination. These harmful components can be substantially reduced by passing the injection through a sterilizing (0.22 μm) filter. To prevent the filter from blocking, a preliminary coarse filter (such as a cigarette filter) should be used first. The filters retain some of the dose, but this can be recovered by following filtration with one or two rinses with 1 ml water. Although filtration can reduce the non-pharmacological harmful consequences of injecting tablets, this remains an unsafe practice due to skin and environmental contamination by particles and microorganisms, and the risks of blood-borne infections from sharing injecting equipment.</p

CHEMICAL COMPOSITION OF THE ESSENTIAL OIL OF CLADANTHUS SCARIOSUS(ASTERACEAE) WILD GROWN IN MOROCCO

Cladanthus Cass. [Syn. Ormenis (Cass.) Cass.] is a genus of the family Asteraceae, endemic to the Mediterranean region and related to the tribe Anthemideae (1). It comprises 15 species including C. scariosus (Ball) Oberpr. & Vogt [Bas. Santolina scariosa; Syn. Ormenis scariosa Litard. & Maire] from Morocco where is concentrates 1/3 of the species of the genus (2). Some of these are perennial, suffruticose and strongly aromatic plants. C. mixta (L.) Chev. is used in Morocco as chamomile and this is commonly called Moroccan chamomile. In the same country, C scariosus is fairly common in open places, on sandstone substrates (3) and is characterized by a strong aromatic character, this has motivated the authors – some of which were previously occupied by other species of the same genus (4) – to undertake such study phytochemical. In this study, the authors present the results of chemical composition of the essential oil of Cladanthus scariosus wild grown in many regions of Morocco (5). Hydrodistillation of C. scariosus aerial parts, collected on the thermo-mediterranean belt of the central High Atlas – Oukeimeden, from Marrakech to Quarzazate – during the flowering phase gave a pale yellow oil. Overall, sixty-four compounds were identified, representing 92.7% of the total components. The main class of the oil was represented by sesquiterpene hydrocarbons (39.8%) with germacrene D (20.7%) as the most abundant component of the class and of the oil. Monoterpene hydrocarbons, oxygenated monoterpenes and oxygenated sesquiterpenes were present in similar amount (14.8%-15.1%). In these classes the main products were α-pinene (4.8%) and sabinene (6.9%) among the monoterpene hydrocarbons, (E)-chrysanthenyl acetate (8.3%) among the oxygenated monoterpenes and τ –muurolol (4.2%) and (E,E)-farnesyl acetate (3.9%) among the oxygenated sesquiterpenes. It is also noteworthy the good presence of chamazulene (7.1%)