2,053 research outputs found
Identificação de neomacho de Jundiá Rhamdia quelen (Quoy e Gaimard, 1824) através do teste de progênie
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Agrárias. Curso de Engenharia de Aquicultura.O objetivo deste estudo foi identificar neomachos de Rhamdia quelen através de teste de progênie. Esse é um método indireto para a produção de lotes monosexo, que evita a aplicação de hormônio nos peixes destinados ao consumo humano, uma vez que o esperado no cruzamento entre neomachos e fêmeas normais são proles 100% femininas. Para os testes de progênie, machos fenotípicos cultivados por oito meses foram selecionados de um lote submetido à masculinização por ingestão de 17α-metil-testosterona (MT) incorporado na ração na dose de 60mg/kg. Cinco machos foram cruzados com um “pool” de ovos de três fêmeas normais e as proles resultantes de cada cruzamento foram cultivadas por 150 dias para que a sexagem das gônadas pudesse ser realizada através da técnica do imprint. O teste do qui-quadrado evidenciou que um macho originou prole com maior proporção sexual de fêmeas (P<0,05), sendo 75,56%. Apesar de não serem proles 100% femininas, existe um forte indício de que este macho seja neomacho, porque a proporção sexual das demais proles apresentou maior presença de machos ou foi balanceada (1:1)
Selected articles from the XXV National Congress of the Italian Society of Geriatric Surgery.
Tailored treatment of intestinal angiodysplasia in elderly
Background: Angiodysplasia of the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and severe anemia in elderly. Different treatments exist for this kind of pathology. Methods: The aim of this work was to study 40 patients treated for intestinal angiodysplasia with two different kind of endoscopic treatments: argon plasma coagulation (APC) and bipolar electrocoagulation (BEC). Results: Age of patients was similar in both groups (76,2 ± 10.8 years vs 74,8 ± 8,7 years, P = 0,005). Angiodysplasia treated were located in small bowel, right colon, left colon, transverse colon and cecum. We analysed number of treatment, recurrence, hospital discharge, needs of blood transfusions before and after endoscopic treatment. Number of treatment was the same in both groups (1,2 ± 0,2 vs 1,1 ± 0,1, P < 0,001). We had more recurrence in patients treated with BEC (4/20 vs 2/20, P < 0,001). Hospital discharge was comparable in both groups (5,3 ± 3,1 days vs 5,4 ± 2,8 years, P < 0.001) Conclusions: Treatment of angiodysplasia in elderly is not easy. Different kinds of treatment could be adopted. APC and BEC are both safe and effective. The choice of a treatment should consider several factors: age, comorbidity, source of bleeding. In conclusion we think that treatment of bleeding for angiodysplasia in elder population should be a tailored treatment. © 2015 Rita Compagna et al., published by De Gruyter Open
Brownian regime of finite- N corrections to particle motion in the XY Hamiltonian mean field model
International audienceWe study the dynamics of the N-particle system evolving in the XY hamiltonian mean field (HMF) model for a repulsive potential, when no phase transition occurs. Starting from a homogeneous distribution, particles evolve in a mean field created by the interaction with all others. This interaction does not change the homogeneous state of the system, and particle motion is approximately ballistic with small corrections. For initial particle data approaching a waterbag, it is explicitly proved that corrections to the ballistic velocities are in the form of independent brownian noises over a time scale diverging not slower than N^(2/5) as N → ∞, which proves the propagation of molecular chaos. Molecular dynamics simulations of the XY-HMF model confirm our analytical findings
Death after an accidental fall of a 101 year old hospitalized patient. Medico-legal implication of falling in geriatrics.
2014 Spring Conference of the Italian Society of Endocrine Surgery - Therapeutic Strategy in Endocrine Surgery
A Genotypic-oriented View of CFTR Genetics Highlights Specific Mutational Patterns Underlying Clinical Macro-categories of Cystic Fibrosis.
Cystic Fibrosis (CF) is a monogenic disease caused by mutations of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The genotype-phenotype relationship in this disease is still unclear, and diagnostic, prognostic and therapeutic challenges persist. We enrolled 610 patients with different forms of CF and studied them from a clinical, biochemical, microbiological and genetic point of view. Overall, 125 different mutated alleles (11 of which with novel mutations and 10 of which complex) and 225 genotypes were found. A strong correlation between mutational patterns at the genotypic level and phenotypic macro-categories emerged. This specificity appears to be largely dependent on rare and individual mutations, as well as on the varying prevalence of common alleles in different clinical macro-categories. However, 19 genotypes appeared to underlie different clinical forms of the disease. The dissection of the pathway from the CFTR mutated genotype to the clinical phenotype allowed to identify at least two components of the variability usually found in the genotype - phenotype relationship. One component seems to depend on the genetic variation of CFTR, the other component on the cumulative effect of variations in other genes and cellular pathways independent from CFTR. The experimental dissection of the overall biological CFTR pathway appears to be a powerful approach for a better comprehension of the genotype - phenotype relationship. However, a change from an allele-oriented to a genotypic-oriented view of CFTR genetics is mandatory, as well as a better assessment of sources of variability within the CFTR pathway
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