Genome sequences of Human Adenovirus 14 isolates from mild respiratory cases and a fatal pneumonia, isolated during 2006-2007 epidemics in North America

<p>Abstract</p> <p>Background</p> <p>Human adenovirus 14 (HAdV-14) is a recognized causative agent of epidemic febrile respiratory illness (FRI). Last reported in Eurasia in 1963, this virus has since been conspicuously absent in broad surveys, and was never isolated in North America despite inclusion of specific tests for this serotype in surveillance methods. In 2006 and 2007, this virus suddenly emerged in North America, causing high attack rate epidemics of FRI and, in some cases, severe pneumonias and occasional fatalities. Some outbreaks have been relatively mild, with low rates of progression beyond uncomplicated FRI, while other outbreaks have involved high rates of more serious outcomes.</p> <p>Methodology and Findings</p> <p>In this paper we present the complete genomic sequence of this emerging pathogen, and compare genomic sequences of isolates from both mild and severe outbreaks. We also compare the genome sequences of the recent isolates with those of the prototype HAdV-14 that circulated in Eurasia 30 years ago and the closely related sequence of HAdV-11a, which has been circulating in southeast Asia.</p> <p>Conclusions</p> <p>The data suggest that the currently circulating strain of HAdV-14 is closely related to the historically recognized prototype throughout its genome, though it does display a couple of potentially functional mutations in the fiber knob and E1A genes. There are no polymorphisms that suggest an obvious explanation for the divergence in severity between outbreak events, suggesting that differences in outcome are more likely environmental or host determined rather than viral genetics.</p

The Eemian lakeland extent in Poland versus stratigraphical position of the middle Polish Glaciations

Na mapie zestawiono 261 wybranych stanowisk interglacjału eemskiego na tle głównych stref marginalnych lądolodów skandynawskich w Polsce. Obecność stanowisk osadów jeziornych z interglacjału eemskiego w strefie wysoczyzn polodowcowych położonych między zasięgami lądolodów warty i odry, przy braku na tym obszarze starszych, to jest z interglacjału lubawskiego, osadów w stanowiskach eemskich, jest kolejnym argumentem przemawiającym za uznaniem obu nasunięć lądolodów (odry i warty) jako stadiałów obrębie jednego zlodowacenia. Zlodowacenie to zajmowałoby pozycję chronostratygraficzną zlodowacenia warty (Lindner, 2005), korelowaną z 6 stadium izotopowym tlenu, czyli około 210-130 ka.The map presents 261 selected sites of the Eemian Interglacial against the background of marginal zones of the Scandinavian Glaciations in Poland (Fig. 1). The appearance of lacustrine deposit sites from the Eemian Interglacial in morainic uplands between the Wartanian and Odranian ice-sheets along with the absence of older interglacial sediments (prior to the Wartanian Glaciation i.e. of the Lublin Interglacial age) at the Eemian sites - is another argument for accepting both the Wartanian and Odranian advances as stadials within a single glaciation. The glaciation would embrace a chronostratigraphic position of the Wartanian Glaciation (Lindner, 2005) as correlated with the 6th oxygen isotope stage i.e. ca 210-130 ka

Biogenic deposites of the Eemian Interglacial at Porzewnica and Marysin near Minsk Mazowiecki (Wegrów Basin-Central Poland)

Ice sheet of the Wartanian Glaciation and their deposits shaped the landscape of the Węgrów Basin. Biogenic lake sediments at Porzewnica and Marysin sites (figs.1, 2) consist of about 5 m thick silts and gyttja, covered by 1.15 m thick sand at Porzewnica and by 8.5 m thick silts and sands at Marysin. In the Porzewnica pollen diagram (fig. 4) there are 7 L PAZ and 1 interzone without sporomorphs. representing vegetation succession during the late Wartanian Glaciation, the protocratic, mesocratic and part of the telocratic phases of the Eemian Interglacial. Spectra of sediments at the Marysin site represent 4 L PAZ of the youngest part of the mesocratic phase and fragments of the telocratic phase of that Interglacial

Software for image recognition of domestic manufacturers dairy drinking products using Raspberry PI

С использованием каскада Хаара и одноплатного компьютера Raspberry Pi была создана программа по распознаванию образа молочного питьевого продукта в видеопотоке. Был проведён эксперимент, показавший целесообразность использования метода обучения модели, а также сделан вывод о резонности применения Raspberry Pi для достижения поставленной задачи. Using the Haar cascade and single-board computer Raspberry Pi, was created a program to recognize the image of a dairy drinking product in a video stream. An experiment that showed the feasibility of using the model training method was conducted, and a conclusion about the reasonableness of using Raspberry Pi to achieve the task was made

The results of reliability tests of semiconductor devices analysis using Python libraries

При сборе большого количества данных об электрических параметрах приборов важно рационально осуществлять анализ получаемых значений. Выводы удобно делать при оценке графических представлений результатов, однако вручную строить графики для каждого параметра является нецелесообразным, в этом могут помочь библиотеки языка программирования Python. Collecting a large amount of data on the electrical parameters of devices, it is important to analyze the obtained values rationally Conclusions can be done easily by a graphical presentation of the results; however, it is impractical to manually build graphs for each parameter. Python programming language libraries can help in this

Forecasting energy characteristics of photoelectric stations by the methods of learning solution trees

В статье представлены результаты прогнозирования выработки электроэнергии фотоэлектрическими (солнечными) электростанциями (ФЭС) методами обучения деревьев решений. Для прогнозирования были использованы деревянные модели, основаны на деревьях решений DecisionTree, GradientBoosting, RandomForest. Для оценки точности прогнозирования оценивались среднеквадратичная ошибка (MSE), средняя абсолютная ошибка (MAE), коэффициент детерминации (R2). At present, the results of forecasting the generation of electricity by photovoltaic (solar) power plants by methods of training decision trees. For forecasting, wooden models was used, based on decision trees DecisionTree, GradientBoosting, RandomForest. To assess the prediction accuracy, the mean square error (MSE), the mean absolute error (MAE), and the coefficient of determination (R2) was estimated

Polycrystalline solar cells electrical characteristics forecasting based on their degradation models

Представлены результаты ускоренных испытаний полупроводниковых фотоэлектрических (солнечных) элементов (СЭ) класса B на основе поликристаллического кремния. Установлено, что автомодельность эксперимента соблюдается при температурах до 150–160° С и уровнях освещения до 2000 Вт/м2. За 168 ч ускоренных испытаний относительная деградация КПД составила 5,8%. Установлена закономерность деградации коэффициента заполнения (ff) и тока короткого замыкания (Isc) СЭ в начальный и конечный момент времени испытаний.In this paper we present the results of accelerated tests B class based solar cells. It is established that the self-similarity of the experiment is observed at temperatures up to 150–160° C and lighting levels up to 2000 W/m2. During over 168 h of accelerated testing the relative degradation of efficiency was 5,8%. The pattern of degradation of the duty cycle (ff) and short-circuit current (Isc) of the solar cells at the initial and final time points of the tests is established

Geology, stratigraphy and palaeoenvironmental evolution of the Stephanorhinus kirchbergensis

The sedimentary succession exposed in the Gorzów Wielkopolski area includes Eemian Interglacial (MIS 5e) or Early Weichselian (MIS 5d–e) deposits. The sedimentary sequence has been the object of intense interdisciplinary study, which has resulted in the identification of at least two palaeolake horizons. Both yielded fossil remains of large mammals, alongside pollen and plant macrofossils. All these proxies have been used to reconstruct the environmental conditions prevailing at the time of deposition, as well as to define the geological context and the biochronological position of the fauna. Optically stimulated luminescence dating of the glaciofluvial layers of the GS3 succession to 123.6 ± 10.1 (below the lower palaeolake) and 72.0 ± 5.2 ka (above the upper palaeolake) indicate that the site formed during the Middle–Late Pleistocene (MIS 6 – MIS 5). Radiocarbon-dating of the lacustrine organic matter revealed a tight cluster of Middle Pleniglacial Period (MIS 3) ages in the range of ~41–32 ka cal bp (Hengelo – Denekamp Interstadials). Holocene organic layers have also been found, with C ages within a range of 4330–4280 cal bp (Neolithic). Pollen and plant macrofossil records, together with sedimentological and geochemical data, confirm the dating to the Eemian Interglacial.This research was supported by grant 0201/2048/18 ‘Life and death of extinctrhino (Stephanorhinus sp.) from Western Poland: a multiproxy palaeoenvironmental approach’ financed by the National Science Centre, Poland. LiDAR DTM data presented in this study were used under academic licences DIO.DFT.DSI.7211.1619.2015_PL_N and DIO.DFT.7211.9874. 2015_PL_N awarded to the Faculty of Earth Sciences and the Environmental Management University of Wrocław, in accordance with the Polish legal regulations of the administration of the Head Office of Land Surveying and Cartography