Preliminary Survey of the Terrestrial Isopods (Isopoda), Millipedes (Diplopoda), Harvestmen (Opiliones), and Spiders (Araneae) of Toft Point Natural Area, Door County, Wisconsin

Toft Point Natural Area is a National Natural Landmark owned and managed by the University of Wisconsin – Green Bay and located on the Lake Michigan shore of Wisconsin’s Door Peninsula. With twelve biotic communities on 700 acres, Toft Point contains considerable biological diversity. We conducted a preliminary survey of the arachnids (spiders and harvestmen, excluding mites and pseudoscorpions), millipedes (diplopods), and terrestrial isopods (Isopoda: Oniscoidea). Sampling occurred on three dates in 2001 using leaf litter collection with Berlese extraction and a timed collection by hand that incorporated a variety of techniques. Specimens from a 1992 survey and assorted collecting events were also used to compile a species list. The list includes five isopods, four millipedes, six harvestmen, and 113 spiders, including 16 new state records (two millipedes and 14 spiders) and 90 new Door County records. Litter collection and sampling in wetland habitats were both especially productive

Migrants et insécurité existentielle

Un peu partout sur le continent africain, les immigrés originaires d’Afrique de l’Ouest sont victimes de violences et de discriminations. En Afrique du Sud, en Côte d’Ivoire ou en République du Congo, le ressentiment monte parmi les populations autochtones. Dans un contexte de crise économique, elles reprochent aux migrants d’accaparer les emplois. C’est le cas à Brazzaville, où il est difficile pour les Ouest-Africains de s’intégrer. Plongés dans une société qui les rejette, ces migrants vivent une insécurité aux multiples visages

Preliminary Survey of the Terrestrial Isopods (Isopoda), Millipedes (Diplopoda), Harvestmen (Opiliones), and Spiders (Araneae) of Toft Point Natural Area, Door County, Wisconsin

Toft Point Natural Area is a National Natural Landmark owned and managed by the University of Wisconsin – Green Bay and located on the Lake Michigan shore of Wisconsin’s Door Peninsula. With twelve biotic communities on 700 acres, Toft Point contains considerable biological diversity. We conducted a preliminary survey of the arachnids (spiders and harvestmen, excluding mites and pseudoscorpions), millipedes (diplopods), and terrestrial isopods (Isopoda: Oniscoidea). Sampling occurred on three dates in 2001 using leaf litter collection with Berlese extraction and a timed collection by hand that incorporated a variety of techniques. Specimens from a 1992 survey and assorted collecting events were also used to compile a species list. The list includes five isopods, four millipedes, six harvestmen, and 113 spiders, including 16 new state records (two millipedes and 14 spiders) and 90 new Door County records. Litter collection and sampling in wetland habitats were both especially productive

Of Masks and Masculinities in Africa

Contemporary forms of precarity, migration, connectivity, and sociality have transformed what it means to be a man in many African communities. Responding with agency and creativity to various incentives and constraints, Africans have adapted practices pertaining to labour, marriage, and sexuality to the exigencies of modern life amid the impacts of European colonialism, rapid urban growth, economic hardship, and political conflict. Drawing upon ethnographic and historical research to study settings in East, West, and Southern Africa, the articles in this special issue review the social changes that have taken place regarding men's roles and assess prospects for the emergence of counter-hegemonic masculinities.</p

Of Masks and Masculinities in Africa

Contemporary forms of precarity, migration, connectivity, and sociality have transformed what it means to be a man in many African communities. Responding with agency and creativity to various incentives and constraints, Africans have adapted practices pertaining to labour, marriage, and sexuality to the exigencies of modern life amid the impacts of European colonialism, rapid urban growth, economic hardship, and political conflict. Drawing upon ethnographic and historical research to study settings in East, West, and Southern Africa, the articles in this special issue review the social changes that have taken place regarding men's roles and assess prospects for the emergence of counter-hegemonic masculinities.</p

Of Masks and Masculinities in Africa

Contemporary forms of precarity, migration, connectivity, and sociality have transformed what it means to be a man in many African communities. Responding with agency and creativity to various incentives and constraints, Africans have adapted practices pertaining to labour, marriage, and sexuality to the exigencies of modern life amid the impacts of European colonialism, rapid urban growth, economic hardship, and political conflict. Drawing upon ethnographic and historical research to study settings in East, West, and Southern Africa, the articles in this special issue review the social changes that have taken place regarding men's roles and assess prospects for the emergence of counter-hegemonic masculinities.</p

Of Masks and Masculinities in Africa

Contemporary forms of precarity, migration, connectivity, and sociality have transformed what it means to be a man in many African communities. Responding with agency and creativity to various incentives and constraints, Africans have adapted practices pertaining to labour, marriage, and sexuality to the exigencies of modern life amid the impacts of European colonialism, rapid urban growth, economic hardship, and political conflict. Drawing upon ethnographic and historical research to study settings in East, West, and Southern Africa, the articles in this special issue review the social changes that have taken place regarding men's roles and assess prospects for the emergence of counter-hegemonic masculinities.</p

Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

Recent efforts to identify treatments for myocardial ischemia reperfusion injury have resulted in the discovery of a novel series of highly potent α,α-disubstituted amino acid-based arginase inhibitors. The lead candidate, (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid, compound 9, inhibits human arginases I and II with IC50s of 223 and 509 nM, respectively, and is active in a recombinant cellular assay overexpressing human arginase I (CHO cells). It is 28% orally bioavailable and significantly reduces the infarct size in a rat model of myocardial ischemia/reperfusion injury. Herein, we report the design, synthesis, and structure−activity relationships (SAR) for this novel series of inhibitors along with pharmacokinetic and in vivo efficacy data for compound 9 and X-ray crystallography data for selected lead compounds cocrystallized with arginases I and II.Fil: Van Zandt, Michael C.. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Whitehouse, Darren L.. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Golebiowski, Adam. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Ji, Min Koo. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Zhang, Mingbao. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Beckett, R. Paul. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Jagdmann, G. Erik. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Ryder, Todd R.. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Sheeler, Ryan. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Andreoli, Monica. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Conway, Bruce. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Mahboubi, Keyvan. Institutes for Pharmaceutical Discovery; Estados UnidosFil: D’Angelo, Gerard. Institutes for Pharmaceutical Discovery; Estados UnidosFil: Mitschler, Andre. Université de Strasbourg; FranciaFil: Cousido Siah, Alexandra. Université de Strasbourg; FranciaFil: Ruiz, Frances X.. Université de Strasbourg; FranciaFil: Howard, Eduardo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina. Université de Strasbourg; FranciaFil: Podjarny, Alberto Daniel. Université de Strasbourg; FranciaFil: Schroeter, Hagen. Mars Incorporated; Estados Unido

Helping the Working Poor: Employer- vs. Employee-Based Subsidies

In the United States and Europe there has been renewed interest in subsidizing firms that employ disadvantaged workers as a means of addressing poverty and other social problems. In contrast, the prevailing practice is largely to provide social welfare benefits directly to individuals. Which approach is better? We re-examine the relative merits of employee- versus employer-based labor market subsidies and conclude there are good reasons to continue to rely on the direct, employee-based approach. In practice, low-wage workers are seldom either low-skill or low-income workers. Furthermore, workers who might quality for a firm-based subsidy are reluctant to so identify themselves for fear of being stigmatized or labeled as needy. Thus, employer-based subsidy programs have lower participation rates and correspondingly higher per capita expenditures than employee-based subsidy programs