8 research outputs found
Volcano plot of gene differentially expressed between statin users and non-users.
<p>The plot shows the log fold-change on the X-axis versus the unadjusted P values (on the–log10 scale) on the Y-axis. The blue and red dots represent genes that showed fold change in either direction that is greater than 0.05 and have unadjusted P value <0.01. Genes that had an FDR-adjusted P value less than 0.05 for differential expression are annotated on the graph.</p
GO biological processes’ enrichment among statin differentially expressed genes.
<p>Adjusted P value: The Benjamini Hochberg Adjusted P value. No. of genes: number of genes in this pathway present among the 18 genes tested.</p><p>GO biological processes’ enrichment among statin differentially expressed genes.</p
Statins’ differentially expressed genes at 10% FDR.
<p>LogFC: log 2 fold change. Adj.p.value: Benjamini Hochberg Adjusted P value</p><p>Statins’ differentially expressed genes at 10% FDR.</p
Study participants’ demographics.
<p>Continuous variables are shown as mean+ standard error of man (SEM). Difference in demographics between statin users and non-users was calculated using Student’s t-test for continuous variables and Chi-square test for categorical variables</p><p>Study participants’ demographics.</p
Summary of logistic regression for persistent systemic inflammation (defined as in upper quartile at both visits for at least 2 biomarkers).
<p>Statistically significant factors are highlighted in bold. For further explanations, see text.</p
Box plot (log scale) of the different biomarkers determined at baseline in COPD patients, smokers with normal lung function and nonsmokers.
<p>For further explanations, see text.</p