Waveforms for Gravitational Radiation from Cosmic String Loops

We obtain general formulae for the plus- and cross- polarized waveforms of gravitational radiation emitted by a cosmic string loop in transverse, traceless (synchronous, harmonic) gauge. These equations are then specialized to the case of piecewise linear loops, and it is shown that the general waveform for such a loop is a piecewise linear function. We give several simple examples of the waveforms from such loops. We also discuss the relation between the gravitational radiation by a smooth loop and by a piecewise linear approximation to it.Comment: 16 pages, 6 figures, Revte

Double-Mode RR Lyrae Variables in the Globular Cluster M3

We present new B-band CCD photometry for five double-mode RR Lyrae (RRd) variables (V68, V79, V87, V99, and V166) in the globular cluster M3. The pulsational behavior of the RRd variables is described. V68 and V87 have been known as RRd variables since 1982, V79 was recently discovered as an RRd (Clement et al.), and our data have identified V99 and V166 as RRd variables (Corwin et al.). Earlier studies of V79 and V166 do not show double-mode behavior, which indicates that these stars have only recently become RRd stars. V166 changed its dominant pulsation mode from fundamental to first overtone in the interval 1992 to 1993. The candidate double-mode variables V28 and V126 do not exhibit clear RRd behavior in the 1992–1993 data

A chi-squared time-frequency discriminator for gravitational wave detection

Searches for known waveforms in gravitational wave detector data are often done using matched filtering. When used on real instrumental data, matched filtering often does not perform as well as might be expected, because non-stationary and non-Gaussian detector noise produces large spurious filter outputs (events). This paper describes a chi-squared time-frequency test which is one way to discriminate such spurious events from the events that would be produced by genuine signals. The method works well only for broad-band signals. The case where the filter template does not exactly match the signal waveform is also considered, and upper bounds are found for the expected value of chi-squared.Comment: 18 pages, five figures, RevTex

Analytic Results for the Gravitational Radiation from a Class of Cosmic String Loops

Cosmic string loops are defined by a pair of periodic functions ${\bf a}$ and ${\bf b}$, which trace out unit-length closed curves in three-dimensional space. We consider a particular class of loops, for which ${\bf a}$ lies along a line and ${\bf b}$ lies in the plane orthogonal to that line. For this class of cosmic string loops one may give a simple analytic expression for the power $\gamma$ radiated in gravitational waves. We evaluate $\gamma$ exactly in closed form for several special cases: (1) ${\bf b}$ a circle traversed $M$ times; (2) ${\bf b}$ a regular polygon with $N$ sides and interior vertex angle $\pi-2\pi M/N$; (3) ${\bf b}$ an isosceles triangle with semi-angle $\theta$. We prove that case (1) with $M=1$ is the absolute minimum of $\gamma$ within our special class of loops, and identify all the stationary points of $\gamma$ in this class.Comment: 15 pages, RevTex 3.0, 7 figures available via anonymous ftp from directory pub/pcasper at alpha1.csd.uwm.edu, WISC-MILW-94-TH-1

In Vivo Cross-Priming of MHC Class I–Restricted Antigens Requires the TAP Transporter

AbstractRecent in vitro evidence suggests two alternative mechanisms by which bone marrow–derived APCs may process exogenous antigens for presentation to CTL in vivo, a phenomenon termed cross-priming. Although in vitro studies have suggested that both TAP-dependent and TAP-independent pathways exist, we have now demonstrated an absolute requirement for a functional TAP for cross-priming to occur in vivo. Bone marrow chimeras reconstituted with marrow from TAP-defective donors develop functional CD8+ CTL, but have APCs with disrupted TAP function. In such chimeras, in vivo priming of naive CTL was observed when antigen was targeted to the ER in a TAP-independent fashion, but cross-priming could not be demonstrated. These results support the TAP-dependent mechanism of cross-priming

Detecting relic gravitational radiation from string cosmology with LIGO

A characteristic spectrum of relic gravitational radiation is produced by a period of ``stringy inflation" in the early universe. This spectrum is unusual, because the energy-density rises rapidly with frequency. We show that correlation experiments with the two gravitational wave detectors being built for the Laser Interferometric Gravitational Observatory (LIGO) could detect this relic radiation, for certain ranges of the parameters that characterize the underlying string cosmology model.Comment: 6 pages, 5 eps figures, Revte

A Closed-Form Expression for the Gravitational Radiation Rate from Cosmic Strings

We present a new formula for the rate at which cosmic strings lose energy into gravitational radiation, valid for all piecewise-linear cosmic string loops. At any time, such a loop is composed of $N$ straight segments, each of which has constant velocity. Any cosmic string loop can be arbitrarily-well approximated by a piecewise-linear loop with $N$ sufficiently large. The formula is a sum of $O(N^4)$ polynomial and log terms, and is exact when the effects of gravitational back-reaction are neglected. For a given loop, the large number of terms makes evaluation ``by hand" impractical, but a computer or symbolic manipulator yields accurate results. The formula is more accurate and convenient than previous methods for finding the gravitational radiation rate, which require numerical evaluation of a four-dimensional integral for each term in an infinite sum. It also avoids the need to estimate the contribution from the tail of the infinite sum. The formula has been tested against all previously published radiation rates for different loop configurations. In the cases where discrepancies were found, they were due to errors in the published work. We have isolated and corrected both the analytic and numerical errors in these cases. To assist future work in this area, a small catalog of results for some simple loop shapes is provided.Comment: 29 pages TeX, 16 figures and computer C-code available via anonymous ftp from directory pub/pcasper at alpha1.csd.uwm.edu, WISC-MILW-94-TH-10, (section 7 has been expanded, two figures added, and minor grammatical changes made.

Cosmic strings, loops, and linear growth of matter perturbations

We describe the detailed study and results of high-resolution numerical simulations of string-induced structure formation in open universes and those with a non-zero cosmological constant. The effect from small loops generated from the string network has also been investigated. We provide a semi-analytical model which can reproduce these simulation results. A detailed study of cosmic string network properties regarding structure formation is also given, including the correlation time, the topological analysis of the source spectrum, the correlation between long strings and loops, and the evolution of long-string and loop energy densities. For models with $\Gamma=\Omega h=0.1--0.2 and a cold dark matter background, we show that the linear density fluctuation power spectrum induced by cosmic strings has both an amplitude at$8 h^{-1}$Mpc,$\sigma_8$, and an overall shape which are consistent within uncertainties with those currently inferred from galaxy surveys. The cosmic string scenario with hot dark matter requires a strongly scale-dependent bias in order to agree with observations.Comment: 60 pages, 24 figure

Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1)

Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built. To highlight some of these issues and share experiences, the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1) was held in November 2013 in conjunction with the SC13 Conference. The workshop featured keynote presentations and a large number (54) of solicited extended abstracts that were grouped into three themes and presented via panels. A set of collaborative notes of the presentations and discussion was taken during the workshop. Unique perspectives were captured about issues such as comprehensive documentation, development and deployment practices, software licenses and career paths for developers. Attribution systems that account for evidence of software contribution and impact were also discussed. These include mechanisms such as Digital Object Identifiers, publication of “software papers”, and the use of online systems, for example source code repositories like GitHub. This paper summarizes the issues and shared experiences that were discussed, including cross-cutting issues and use cases. It joins a nascent literature seeking to understand what drives software work in science, and how it is impacted by the reward systems of science. These incentives can determine the extent to which developers are motivated to build software for the long-term, for the use of others, and whether to work collaboratively or separately. It also explores community building, leadership, and dynamics in relation to successful scientific software

Molecular Dissection of Psoriasis: Integrating Genetics and Biology

Psoriasis is a common and debilitating disease of the skin, nails, and joints, with an acknowledged but complex genetic basis. Early genome-wide linkage studies of psoriasis focused on segregation of microsatellite markers in families; however, the only locus consistently identified resided in the major histocompatibility complex. Subsequently, several groups mapped this locus to the vicinity of HLA-C, and two groups have reported HLA-Cw6 itself to be the major susceptibility allele. More recently, the development of millions of single-nucleotide polymorphisms, coupled with the development of high-throughput genotyping platforms and a comprehensive map of human haplotypes, has made possible a genome-wide association approach using cases and controls rather than families. Taking advantage of these developments, we participated in a collaborative genome-wide association study of psoriasis involving thousands of cases and controls. Initial analysis of these data revealed and/or confirmed association between psoriasis and seven genetic loci—HLA-C, IL12B, IL23R, IL23A, IL4/IL13, TNFAIP3, and TNIP1—and ongoing studies are revealing additional loci. Here, we review the epidemiology, immunopathology, and genetics of psoriasis, and present a disease model integrating its genetics and immunology