Anisotropic focusing characteristics of micro-domain structures within crystalline Sr_0.61Ba_0.39Nb₂O₆ : the crystal ball

We report the anisotropic focusing characteristics of a spherically configured region of micro-domains that have been induced within a cubic shaped crystal of Ce:doped Sr0.61Ba0.39Nb2O6. The internal spherical structure focuses extraordinary polarised light, but not ordinary polarised. The spherical region, which is easily observed via scattering, is formed as the crystal cools down, after a repoling cycle through the Curie temperature, with an applied field. Analytic modelling of the thermal gradients that exist within the crystal during cooling reveals a small (< 1°) temperature difference between the central and outside regions. The similarity in shape between these temperature profiles and the observed scattering region suggests a possible mechanism for the growth of this spherical micro-domained structure

Milk yields from feeding maize silage and meat-and-bone meal to Friesian cows grazing a tropical grass and legume pasture

Twenty Friesian cows in mid-lactation were used in a 2x2 factorial experiment to determine the responses in milk yield, milk composition and liveweight to maize silage supplement (3 kg dry matter/cow.d, or free access during the day) with or without a meat-and-bone meal supplement (5 silage: 1 meat-and-bone meal, on a dry matter basis). Cows grazed green panic (Panicum maximum var. trichoglume) and glycine (Neonotonia wightii cv. Tinaroo) mixed pastures at 2.5 cowslha. Experimental treatments were maintained for eight weeks after which cows grazed as one group on unsupplemented pasture for a further eight weeks. Milk yields averaged 14.7 and 16.0 kg/cow.d for the low and high silage levels (P < 0.01), and 15.8 and 14.8 kg/cow.d with and without meat-and-bone meal (P < 0.05). There was a residual effect of 1.2 kg milk/cow.d (P < 0.05) for eight weeks after the experimental period from feeding silage at the high level. Feeding meat-and-bone meal reduced milk fat percentage from 3.61 to 3.30% (P< 0.05). Protein yield and the short-chain fatty acid (C4-C16) content of milk fat were increased by increasing the level of intake of silage (P < 0.01), while feeding meat-and-bone meal increased protein yield (P < 0.05), but decreased the short-chain fatty acid content of milk fat (P < 0.05). Cows lost an average of 15.2 kg liveweight at the low silage level and gained 6.7 kg at the high silage level (P< 0.01) over the eight weeks of experimental feeding

Imaging the Haro 6-10 Infrared Companion

We present an infrared imaging study of the low-mass pre-main-sequence binary system Haro 6-10. This system is one of a handful in which the optically visible primary has the characteristics of a normal T Tauri star, while the secondary is a so-called "infrared companion" (IRC), a strongly extincted object that emits most of its luminosity in the infrared. A speckle holographic technique was used to produce nearly diffraction-limited images on three nights over a 1 yr period starting in late 1997. The images show that the IRC is obscured and surrounded by a compact, irregular, and variable nebula. This structure is in striking contrast to the well-ordered edge-on disk associated with HK Tauri B, the extincted companion to another T Tauri star of similar age. A new, resolved intensity peak was found 0".4 southwest of the IRC. We suggest that it may represent light scattered by a clump of dusty material illuminated by starlight escaping along an outflow-carved cavity in the IRC envelope. The primary star became fainter and the companion became more extended during the observing period

Chemical containment and eradication of screw− worm incursions in Australia

Screwworms are obligate, invasive parasites of warm-blooded animals. The female flies lay batches of eggs at the edge of wounds or other lesions. These eggs hatch to larvae or screw-worms which feed on affected animals for 6-7 days, burrowing deeply into subcutaneous tissues and causing severe trauma to animals, production loss and potentially death. Susceptible sites include wounds resulting from management practices such as castration, de-horning and ear tagging and lesions caused by the activities of other parasites such as buffalo flies and ticks. The navels of the new born and the vulval region of their mothers following parturition are highly susceptible and body orifices such as nose and ears are also frequent targets for ovipositing screwworm flies. The Old World screw-worm, Chrysomya bezziana (OWS) is considered one of the most serious exotic insect pest threatening Australia's livestock industries and is endemic in a number of our closest neighbouring countries. New World screwworm (NWS), Cochliomyia hominivorax, endemic to South America, has also entered Australia on at least 2 occasions. Many tropical and subtropical areas of Australia are suitable for the establishment of OWS and the potential range is expected to increase with climate change. The Australian screwworm preparedness strategy indicates a program of containment with chemical treatments followed by eradication of OWS using sterile male release and parasiticides. However, there is no longer an operational OWS sterile insect screw-worm facility anywhere in the world and establishing a large scale production facility would most optimistically take at least 2 years. In the interim, containment would be almost totally dependent on the availability of effective chemical controls. A review of chemical formulations available for potential use against OWS in Australia found that currently only one chemical, ivermectin administered by subcutaneous injection (s.c.) is registered for use against OWS and that many of the chemicals previously shown to be effective against OWS were no longer registered for animal use in Australia.18 From this review a number of Australian-registered chemicals were recommended as a priority for testing against OWS. The Australian Pesticides and Veterinary Medicines Authority (APVMA) can issue an emergency use permit for use of pesticides if they are registered in Australia for other animal uses and shown to be effective against OWS. This project tested the therapeutic and prophylactic efficacy of chemicals with potential for use in the treatment and control of OWS

Observation of Buried Phosphorus Dopants near Clean Si(100)-(2x1) with Scanning Tunneling Microscopy

We have used scanning tunneling microscopy to identify individual phosphorus dopant atoms near the clean silicon (100)-(2x1) reconstructed surface. The charge-induced band bending signature associated with the dopants shows up as an enhancement in both filled and empty states and is consistent with the appearance of n-type dopants on compound semiconductor surfaces and passivated Si(100)-(2x1). We observe dopants at different depths and see a strong dependence of the signature on the magnitude of the sample voltage. Our results suggest that, on this clean surface, the antibonding surface state band acts as an extension of the bulk conduction band into the gap. The positively charged dimer vacancies that have been observed previously appear as depressions in the filled states, as opposed to enhancements, because they disrupt these surface bands.Comment: 4 pages, 3 figures. TeX for OSX from Wierde

Policy opportunities

Recommendations are given regarding National Science Foundation (NSF) astronomy programs and the NASA Space Astrophysics program. The role of ground based astronomy is reviewed. The role of National Optical Astronomy Observatories (NOAO) in ground-based night-time astronomical research is discussed. An enhanced Explored Program, costs and management of small and moderate space programs, the role of astrophysics within NASA's space exploration initiative, suborbital and airborne astronomical research, the problems of the Hubble Space Telescope, and astronomy education are discussed. Also covered are policy issues related to the role of science advisory committees, international cooperation and competition, archiving and distribution of astronomical data, and multi-wavelength observations of variable sources

Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology

Buffalo flies (Haematobia irritans exigua) (BF) and closely related horn flies (Haematobia irritans irritans) (HF) are invasive haematophagous parasites with significant economic and welfare impacts on cattle production. Wolbachia are intracellular bacteria found widely in insects and currently of much interest for use in novel strategies for the area wide control of insect pests and insect-vectored diseases. In this paper, we report the transinfection of BF towards the development of area-wide controls

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

BackgroundAtopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation. Loss-of-function mutations in the gene encoding filaggrin (FLG) are a highly significant risk factor for atopic disease, but the molecular mechanisms leading to dermatitis remain unclear.ObjectiveWe sought to interrogate tissue-specific variations in the expressed genome in the skin of children with AD and to investigate underlying pathomechanisms in atopic skin.MethodsWe applied single-molecule direct RNA sequencing to analyze the whole transcriptome using minimal tissue samples. Uninvolved skin biopsy specimens from 26 pediatric patients with AD were compared with site-matched samples from 10 nonatopic teenage control subjects. Cases and control subjects were screened for FLG genotype to stratify the data set.ResultsTwo thousand four hundred thirty differentially expressed genes (false discovery rate, P < .05) were identified, of which 211 were significantly upregulated and 490 downregulated by greater than 2-fold. Gene ontology terms for “extracellular space” and “defense response” were enriched, whereas “lipid metabolic processes” were downregulated. The subset of FLG wild-type cases showed dysregulation of genes involved with lipid metabolism, whereas filaggrin haploinsufficiency affected global gene expression and was characterized by a type 1 interferon–mediated stress response.ConclusionThese analyses demonstrate the importance of extracellular space and lipid metabolism in atopic skin pathology independent of FLG genotype, whereas an aberrant defense response is seen in subjects with FLG mutations. Genotype stratification of the large data set has facilitated functional interpretation and might guide future therapy development

The atmospheres of the hot-Jupiters Kepler-5b and Kepler-6b observed during occultations with Warm-Spitzer and Kepler

This paper reports the detection and the measurements of occultations of the two transiting hot giant exoplanets Kepler-5b and Kepler-6b by their parent stars. The observations are obtained in the near infrared with Spitzer Space Telescope and at optical wavelengths by combining more than a year of Kepler photometry. The investigation consists of constraining the eccentricities of these systems and of obtaining broad band emergent spectra for individual planets. For both targets, the occultations are detected at 3 sigma level at each wavelength with mid-occultation times consistent with circular orbits. The brightness temperatures of these planets are deduced from the infrared observations and reach T=1930+/-100K and T=1660+/-120K for Kepler-5b and Kepler-6b respectively. We measure optical geometric albedos A_g in the Kepler bandpass and find A_g=0.12+/-0.04 for Kepler-5b and A_g=0.11+/-0.04 for Kepler-6b leading to an upper limit for the Bond albedo of A_B < 0.17 in both cases. The observations for both planets are best described by models for which most of the incident energy is redistributed on the dayside, with only less than 10% of the absorbed stellar flux redistributed to the night side of these planets. The data for Kepler-5b favor a model without a temperature inversion, whereas for Kepler-6b they do not allow distinguishing between models with and without inversion.Comment: 26 pages, 18 figures, 3 tables, submitted to Ap