18 research outputs found
Asymmetry in volume between dominant and nondominant upper limbs in young tennis players
This study aimed at demonstrating the asymmetry in volume between the dominant and nondominant upper limbs in tennis players, controlled for maturity status. Upper limb volumes on both sides were calculated in 72 tennis players and 84 control subjects, using the truncated cone method. The participants’ maturity status was determined using the predicted age at peak height velocity (PHV). The results showed significant larger side-to-side asymmetry in volume in tennis groups thanin control groups. These findings suggested that, even before PHV, specific-sport adaptations occurred in the dominant upper limb in tennis players.<br /
Muscle coordination during topspin forehand drive in young tennis players
Purpose:
The aim of this study was to assess the timing of muscle activation during the acceleration phase of topspin forehand drives in young tennis players.
Synthesis:
The activity of six muscles was recorded using surface electromyography during topspin forehand drives in 22 players (9–17 years). The timing of muscle activation was characterized by the onset of EMG bursts during the acceleration stage.
Conclusion:
The proximal-to-distal sequential muscle activity was observed for the agonist muscles while the antagonist muscles were recruited at the end of the acceleration stage. This sequential muscle activity was common to all participants whatever their abilities
Microfluidic Approaches for the Study of Emulsions: Transport of Solutes
International audienceMolecular transport as an ageing process in emulsions is revisited using microfluidic droplet production, manipulation and analysis. We show how microfluidic systems provide extremely quantitative insights into the phenomenon. We designed microfluidic systems to address the specificity of molecular transport in fluorinated oils and showed the role of the surfactant solubilised in the oil phase on the time scale of the exchange and rationalize the effect of water soluble additives on the exchange rate. Finally, we also demonstrate that the droplet packing influences the exchange rate through the number of first neighbours
Microfluidic Approaches for the Study of Emulsions: Transport of Solutes
Molecular transport as an ageing process in emulsions is revisited using microfluidic droplet production, manipulation and analysis. We show how microfluidic systems provide extremely quantitative insights into the phenomenon. We designed microfluidic systems to address the specificity of molecular transport in fluorinated oils and showed the role of the surfactant solubilised in the oil phase on the time scale of the exchange and rationalize the effect of water soluble additives on the exchange rate. Finally, we also demonstrate that the droplet packing influences the exchange rate through the number of first neighbours
Deciphering the Impact of HER2 Alterations on Non-Small-Cell Lung Cancer: From Biological Mechanisms to Therapeutic Approaches
Despite the recent increase in the number of types of treatments, non-small-cell lung cancer (NSCLC) remains the major cause of death from cancer worldwide. So, there is an urgent need to develop new therapeutic strategies. The HER2 gene codes for tyrosine kinase receptor whose alterations are known to drive carcinogenesis. HER2 alterations, including amplification, mutations, and overexpression, have been mainly described in breast and gastric cancers, but up to 4% of NSCLC harbor actionable HER2 mutations. HER2-targeted therapy for NSCLC with trastuzumab, pertuzumab, and trastuzumab emtansine has failed to demonstrate an improvement in survival. Nevertheless, recent data from phase II trials have shed light on promising specific therapies for HER2-mutant NSCLC such as trastuzumab deruxtecan. Herein, we aimed to provide an updated review on the biology, epidemiology, molecular testing, and therapeutic strategies for NSCLC with HER2 molecular alterations
Ultrasonic transducers based on undoped lead-free (K0.5Na0.5)NbO3 ceramics
International audienc
Nanotubes-Porphyrine suspensions optimisation for energy transfer
Chemical functionalization of carbon nanotubes is one of the key challenges towards their use in opto-electronic devices. This technique aims at combining the great transport properties of nanotubes with the versatility of the optical properties of organic molecules. “π-stacking” functionalization of single wall carbon nanotubes with porphyrin molecules has been achieved and energy transfer has been observed from the molecules to the nanotubes by means of luminescence experiments. Nevertheless, these first trials have been performed on suspensions presenting poor stability and low photoluminescence yield. We present here a new process of functionalization that enhances the properties of these suspensions. First, the new suspensions are now stable for months ( as compared with a few days in previous works). The luminescence of these suspensions is also enhanced by more than one order of magnitude in comparison with reference. The good stability and the high luminescence yield will allow more detailed study of the electronic processes occuring in these complexes. Secondly, the nanotubes luminescence is preserved when they are deposited on a surface demonstrating that porphyrin molecules act as a protection shield for the tubes. This latter property is very interesting in view of applications such as photovoltaic cells or fundamental studie