10 research outputs found

    Transcriptome model.

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    <p>Here are the prior probabilities of cattle being infected based on previous experience. Each profiles mixture has structure as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050147#pone-0050147-g004" target="_blank">Figure 4</a>.</p

    Number of mapped reads.

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    <p>Number of reads mapped against informative loci.</p

    Gene expression changes.

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    <p>Gene expression changes.</p

    Number of reads.

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    <p>Number of reads from different pooled transcriptome samples and the total number of reads mapped against the Btau 4.0 reference genome.</p

    Symbolic representation of classification profiles mixture.

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    <p>Here the mixture components indicate the fraction of all hits mapping against loci used to build a profile. Transition frequencies across introns match the Illumina coverage density at each particular splice site.</p

    Example of IFN- and IL17A unnormalized gene expression changes in response to bTB.

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    <p>On these GBrowse views we show coverage for mapped RNA-Seq reads along with Illumina short reads spanning across introns, i.e. cDNA reads that that partially map to two different exons thus anchoring the exonic boundaries. Here the control reads are the reads from TCT1 pool.</p
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