The sociological view and organization theory

The aim of our contribution is to present a review, albeit partial, of the prevailing sociological approaches and topics concerning organization theory. We focused on two of the main American journals of sociology: the American Journal of Sociology (AJS, the official journal of the American Sociological Association) and the American Sociological Review (ASR). We focused our analysis on articles published between 2000 to 2015.For the analysis of the selected articles we used a template considering authors’ affiliation, main subjects, methodology, approach, references to Thompson’s work. In the paper we present a qualitative description of prevailing approaches and topics, discuss the cross fertilization between general sociological theory and organization studies and the neglected connections with Thompson

Modelling transpiration of greenhouse gerbera (Gerbera jamesonii H. Bolus) grown in substrate with saline water in a Mediterranean climate

Gerbera plants were grown in semi-closed rockwool culture under greenhouse conditions in different seasons in a Mediterranean climate. The plants were irrigated using either fresh (FW; 1.0 mol m−3NaCl)or moderately saline (SW; 9.0 mol m−3NaCl) water. In autumn, NaCl concentration did not influence significantly plant growth, flower production and transpiration (E), which instead were reduced in springin the plants irrigated with SW. In both seasons, water salinity did not affect leaf stomatal resistance (rl),which was determined by the inversion of the Penman–Monteith (PM) equation or measured with a diffusion porometer. The PM formula and two regression equations were calibrated and validated for estimating the hourly rate of daytime transpiration (Ed); a regression model was also fit to nocturnal transpiration (En). Regression models predicted Edas a function of vapour pressure deficit (VPD) and/or the radiation intercepted by the canopy. Leaf area index (LAI), which is required by all the equations, was modelled as function of crop thermal time (i.e. growing degree days). The PM model predicted Ed using a constant value of rl. Model calibration and validation were performed using independent data sets. The irrigation with FW or SW did not require a different calibration of transpiration models. Both PM formula and regression equations provided accurate estimates of Ed; fitted equations explained between 80% and96% of the variance in measured Ed. A linear regression of En against (LAI·VPD) accounted for 92% of measured En

Low fermentable oligo-di-and mono-saccharides and polyols (Fodmaps) or gluten free diet: What is best for irritable bowel syndrome?

Irritable Bowel Syndrome (IBS) is a very common functional gastrointestinal disease. Its pathogenesis is multifactorial and not yet clearly defined, and hence, its therapy mainly relies on symptomatic treatments. Changes in lifestyle and dietary behavior are usually the first step, but unfortunately, there is little high-quality scientific evidence regarding a dietary approach. This is due to the difficulty in setting up randomized double-blind controlled trials which objectively evaluate efficacy without the risk of a placebo effect. However, a Low Fermentable Oligo-, Di-and Mono-saccharides And Polyols (FODMAP) Diet (LFD) and Gluten Free Diet (GFD) are among the most frequently suggested diets. This paper aims to evaluate their possible role in IBS management. A GFD is less restrictive and easier to implement in everyday life and can be suggested for patients who clearly recognize gluten as a trigger of their symptoms. An LFD, being more restrictive and less easy to learn and to follow, needs the close supervision of a skilled nutritionist and should be reserved for patients who recognize that the trigger of their symptoms is not, or not only, gluten. Even if the evidence is of very low-quality for both diets, the LFD is the most effective among the dietary interventions suggested for treating IBS, and it is included in the most updated guidelines

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

Pediatric T-ALL patients have a worse outcome compared to BCP-ALL patients and they could benefit from new prognostic marker identification. Alteration of CRLF2 gene, a hallmark correlated with poor outcome in BCP-ALL, has not been reported in T-ALL. We analyzed CRLF2 expression in 212 T-ALL pediatric patients enrolled in AIEOP-BFM ALL2000 study in Italian and German centers. Seventeen out of 120 (14.2%) Italian patients presented CRLF2 mRNA expression 5 times higher than the median (CRLF2-high); they had a significantly inferior event-free survival (41.2%±11.9 vs. 68.9%±4.6, p=0.006) and overall survival (47.1%±12.1 vs. 73.8%±4.3, p=0.009) and an increased cumulative incidence of relapse/resistance (52.9%±12.1 vs. 26.2%±4.3, p=0.007) compared to CRLF2-low patients. The prognostic value of CRLF2 over-expression was validated in the German cohort. Of note, CRLF2 over-expression was associated with poor prognosis in the high risk (HR) subgroup where CRLF2-high patients were more frequently allocated. Interestingly, although in T-ALL CRLF2 protein was localized mainly in the cytoplasm, in CRLF2-high blasts we found a trend towards a stronger TSLP-induced pSTAT5 response, sensitive to the JAK inhibitor Ruxolitinib. In conclusion, CRLF2 over-expression is a poor prognostic marker identifying a subset of HR T-ALL patients that could benefit from alternative therapy, potentially targeting the CRLF2 pathway