Tracing Communications and Computational Workload in LJS (Lennard-Jones with Spatial Decomposition)

LJS (Lennard-Jones with Spatial decomposition) is a molecular dynamics application developed by Steve Plimpton at Sandia National Laboratories [1]. It performs thermodynamic simulations of a system containing fixed large number (millions) of atoms or molecules confined within a regular, three-dimensional domain. Since the simulations model interactions on atomic scale, the computations carried out in a single timestep (iteration) correspond to femtoseconds of the real time. Hence, a meaningful simulation of the evolution of the system's state typically requires a large number (thousands and more) of timesteps. The particles in LJS are represented as material points subjected to forces resulting from interactions with other particles. While the general case involves N-body solvers, LJS implements only pair-wise material point interactions using derivative of Lennard-Jones potential energy for each particle pair to evaluate the acting forces. The velocities and positions of particles are updated by integrating Newton's equations (classical molecular dynamics). The interaction range depends on the modeled problem type; LJS focuses on short-range forces, implementing a cutoff distance rc outside which the interactions are ignored. The computational complexity of O(N2), characteristic for systems with long-range interactions, is therefore substantially alleviated. LJS deploys spatial decomposition of the domain volume to distribute the computations across the available processors on a parallel computer. The decomposition process uniformly divides parallelepiped containing all particles into volumes equal in size and as close in shape to a cube as possible, assigning each of such formed cells to a CPU. The correctness of computations requires the positions of some particles (depending on the value of rc) residing in the neighboring cells to be known to the local process. This information is exchanged in every timestep via explicit communication with the neighbor nodes in all three dimensions (for details see [2]). LJS also takes the advantage of the third Newton's law to calculate the force only once per particle pair; if the involved particles belong to cells located on different processors, the results are forwarded to the other node in a "reverse communication" phase. Besides communications occurring in every iteration, additional messages are sent once every preset number of timesteps. Their purpose is to adjust cell assignments of particles due to their movement. To minimize the overhead of the construction of particle neighbor lists, LJS replaces rc with extended cutoff radius rs (rs > rc), which accounts for possible particle movement before any list updates need to be carried out. Due to a relatively small impact of that phase on the overall behavior of the application, we ignored it in our analysis

The "MIND" Scalable PIM Architecture

MIND (Memory, Intelligence, and Network Device) is an advanced parallel computer architecture for high performance computing and scalable embedded processing. It is a Processor-in-Memory (PIM) architecture integrating both DRAM bit cells and CMOS logic devices on the same silicon die. MIND is multicore with multiple memory/processor nodes on each chip and supports global shared memory across systems of MIND components. MIND is distinguished from other PIM architectures in that it incorporates mechanisms for efficient support of a global parallel execution model based on the semantics of message-driven multithreaded split-transaction processing. MIND is designed to operate either in conjunction with other conventional microprocessors or in standalone arrays of like devices. It also incorporates mechanisms for fault tolerance, real time execution, and active power management. This paper describes the major elements and operational methods of the MIND architecture

Educational role of the nurse in relation to sexual behavior of junior high school students

Human sexuality and sexuality in modern times are widely discussed topics. There are many publications that deal with this issue. This is perhaps due to the following global. socio-cultural changes, the return of which is unknown in the long run. The transformations concern the perception of a sense of gender identity. Scholars wanting to capture this extremely rich reality in a certain framework using a variety of tools. They do this rarely bypassing contexts, in line with prevailing trends, which prevents them from looking objectively at the subject of their research. Such research germinates with information chaos that floods us all pages.Aim : The purpose of the work is the educational role of the nurse in youth attitudes towards sexual behavior.Material and Methods :The research was carried out at the turn of April and June 2014. The study involved 94 students from two schools from the Junior High School in Wólka Pełkińska, Podkarpackie Province and from G Junior High School    No. 9 in Lublin, Lubelskie Province. The diagnostic method that was used in the study was the diagnostic survey. The research tool used was the scale "Attitudes of junior high school students towards sexual behavior". It consists of 21 questions, of which eight are questions from the record. The database was created and statistical analyzes were carried out based on Statistica 9.1 computer software ( StatSoft , Poland).Rezults : The relationships that were shown in the description of the research of this work could result in pedagogical practice. Knowing what relationships prevail in the chosen topic, one could take specific pedagogical actions. Such activities would be, for example, the orientation of school curricula of knowledge subjects to family life, and more specifically topics in the field of premarital chastity as well as sex education. However, this process could not be left without control or specifically planned actions. Conclusion : Selected research tools have proved to meet the needs of the research problem posed. Thanks to the interpretation of the results obtained thanks to them, it turned out that there was a relationship that was sought in the research. It says that the attitudes of junior high school students towards sexual behavior are directly related to social conditions. The hypotheses put forward at work proved successful - the gender structure differentiates attitudes of junior high school students towards sexual behavior

Analysis, Tracing, Characterization and Performance Modeling of Select ASCI Applications for BlueGene/L Using Parallel Discrete Event Simulation

Caltech's Jet Propulsion Laboratory (JPL) and Center for Advanced Computer Architecture (CACR) are conducting application and simulation analyses of Blue Gene/L[1] in order to establish a range of effectiveness of the architecture in performing important classes of computations and to determine the design sensitivity of the global interconnect network in support of real world ASCI application execution

Quality of life of patients undergoing hymenoptera venom immunotherapy

Hymenoptera stings are one of the main causes of anaphylaxis in Europe [1] . Clinical observation shows that the most dangerous effects are those that develop immediately after the sting[2] . Most often, allergic symptoms occur within 5 to 20 minutes. There are reactions starting after 2 hours and sometimes even after 72 hours. The group of patients at risk of more severe reactions are atopic patients, patients with skin mastocytosis , the elderly, burdened with additional diseases. The highest mortality rate is observed in people over 50 years of age [3] . Aim : The aim of this study is to evaluate and compare parameters of quality of life, anxiety and anxiety among patients who have undergone immunotherapy for Hymenoptera venoms. Material and Methods : The research was conducted at the turn of January and February 2019. The study involved 100 patients desensitized to hymenoptera venoms in the Department of Allergology and Lung Diseases of the Provincial Specialist Hospital named after of Stefan Cardinal Wyszyński in Lublin. The diagnostic method that was used in the study was the diagnostic survey. The research tool used was the questionnaire: The World Health Organization Quality Of Life (WHOQOL) -BREF (short version of the questionnaire assessing the quality of life) extended by the author's questionnaire. The database was created and statistical analyzes were carried out based on Statistica 9.1 computer software. ( StatSoft, Poland).   Rezults : The vast majority of respondents said that their quality of life is good or very good. As much as 82% gave such an answer. Only seven of the respondents rated their quality of life as bad or very bad. 11% of respondents could not determine the level of quality of their lives. The respondents gave similar satisfaction to their health condition. As many as 74% of respondents declare that they are satisfied or very happy with their health. A quarter of the respondents could not determine whether they were satisfied or not about their health. Conclusion :      In allergy to hymenoptera insects, a significant impact of the disease on the emotional, professional, social and implemented sphere is observed. The previous experience of anaphylaxis symptoms plays a significant role here, but more importantly anxiety associated with their reoccurrence, which is usually the cause of a deterioration in comfort of life, a sense of security risk. That is why proper education conducted simultaneously with patients' immunotherapy is so important. This has a significant impact on the quality of life of patients allergic and immunotherapy to Hymenoptera venoms

Professional burnout of doctors in Poland and in the world. Research review

The work of a doctor is one of the most demanding. It requires not only a great deal of knowledge, but also a lot of commitment, responsibility and often devoting one's private life. It is called a prestigious job for a reason. Unfortunately, it is also very absorbing both mentally and physically. Increasing stress leads to emotional exhaustion, and its consequence may be burnout

Case Report of Suspected Rhabdomyolysis during Treatment with Trabectedin in a Patient with Metastatic Leiomyosarcoma

Trabectedin has been reported to occasionally induce rhabdomyolysis. In the present case, continuation of trabectedin was maintained despite suspected rhabdomyolysis related to trabectedin. Creatinine kinase levels dropped to normal levels. We suggest that continuation of trabectedin despite suspected rhabdomyolysis was safe in this specific patient