Vorrichtung zur Aufnahme einer Fluessigkeit sowie Vorrichtung zur Aufbringung von Fluessigkeiten auf Probentraeger und Verfahren hierzu

DE 102007041071 A1 UPAB: 20090403 NOVELTY - The fluid reception device for supplying the fluid on sample carrier (8), comprises recesses (9), whose base has holes, which are formed so that the capillary pressure in the respective hole is greater than the pressure produced through the fluid in the respective recess. The hole has a diameter of 50 mu m and a length of 1200 mu m and/or 200 mu m. The device represents a multi-corrugated plate, which has 96, 384 or 1536 corrugations and represents a micro-corrugated plate (4). The corrugated base of the multi-corrugated plate has thin glass capillaries as the hole. DETAILED DESCRIPTION - The fluid reception device for supplying the fluid on sample carrier, comprises recesses (9), whose base has holes, which are formed so that the capillary pressure in the respective hole is greater than the pressure produced through the fluid in the respective recess. The hole has a diameter of 50 mu m and a length of 1200 mu m and/or 200 mu m. The device represents a multi-corrugated plate, which has 96, 384 or 1536 corrugations and represents a micro-corrugated plate (4). The corrugated base of the multi-corrugated plate has thin glass capillaries as the hole. The corrugated base of the multi-corrugated plate is formed from a glass plate or an adhesive or laminated plastic foil. The multi-corrugated plate is sealed towards the top through a flexible membrane. INDEPENDENT CLAIMS are included for: (1) a device for supplying the fluid on sample carrier; and (2) method for supplying the fluid on sample carrier. USE - Fluid reception device for supplying the fluid on sample carrier useful for the analysis of substance in biotechnology field. ADVANTAGE - The fluid reception device avoids cleaning and disinfection of sample container and ensures simple, safe and economical analysis of sample in accurate and time consuming manner by avoiding the danger of contamination of the sample

Immediate Drop on Demand Technology (I-DOT): Poster presented Forum Life Science 2015, 9th International Congress and Exhibition, 11-12 March 2015, Garching, Germany

The handling and dosing of cells is the most critical step in the microfabrication of 3D-cell-based assay systems for screening and toxicity testing applications. The use of robotic workstations for liquid handling has increased enormously over the last decades, in order to meet the requirements for high accuracy and high throughput of current bioanalytics. The immediate drop on demand technology (I-DOT) overcomes the challenge of dispensing cells in a small volume precisely and with low shear stress. I-DOT provides a fast and flexible non-contact liquid handling system enabling dispensing cells and liquid without the risk of cross-contamination to a precise volume even in nanoliter range