68 research outputs found

    Adolescent Pregnancy: A Case-Series Study of 112 Adolescent Mothers and Their Newborns

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    Background Although declining, adolescent pregnancy remains an important health concern and is associated with adverse maternal and fetal outcomes. We aimed to characterize adolescent pregnancy in a level II hospital and the observed maternal, fetal, and perinatal complications. Methods We conducted a case-series study of five-years duration with adolescent mothers and their newborns. We collected sociodemographic, obstetric, and neonatal data through chart review and conducted a comparison analysis between newborns who needed hospitalization and those who did not. Results We identified 112 newborns with adolescent mothers. Most pregnancies were unplanned (89.3%) and the start of pregnancy surveillance was late. The most frequent complications were intrauterine growth restriction, oligohydramnios, and threatened preterm labor. Prematurity was found in 9.8% of the newborns and 0.9% had less than 32 weeks at the time of birth. Thirteen newborns (11.6%) needed hospitalization in the neonatal intensive care unit, with three (23%) needing invasive ventilation. The main diagnoses of admission were prematurity, social risk, low birth weight, feeding difficulties, and newborn respiratory distress syndrome. Hospitalization seemed associated with less frequent breastfeeding. Among the hospitalized newborns, there was a high rate of discharge at the care of a relative or an institution (30.8%). Surprisingly, surveillance during pregnancy did not seem to differ between newborns that needed hospitalization and those that did not. Discussion Adolescent pregnancy is associated with poor surveillance as well as obstetric and neonatal complications. Newborns of adolescent mothers have a high hospitalization rate, but further investigations are needed to fully understand the contributing factors. The creation of multidisciplinary teams is fundamental for reducing complications, and appropriate reproductive health programs should focus on reducing adolescent pregnancy through better access to education and contraception.info:eu-repo/semantics/publishedVersio

    Seletividade de espiromesifeno a adultos de Chrysoperla externa (Neuroptera: Chrysopidae) em condições de laboratório.

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    Visando mensurar os efeitos dos inseticidas clotianidina, diafentiurom, imidaclopride, espiromesifeno e tiametoxam, utilizados no controle da boca-branca na cultura do tomateiro, sobre adultos de Chrysoperia externa (Neuroptera: Chrysopidae), bioensaios foram realizados em condições de laboratório, utilizando-se metodologias padrão recomendadas pela IOBC.Resumo PDF 1756-

    Toxicidade de inseticidas utilizados no tomateiro sobre larvas de terceiro instar de Chrysoperia externa (Neuroptera: Chrysopidae).

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    Objetivou-se com o presente estudo avaliar o impacto dos inseticidas clotianidina, diafentiurom, imidaclopride, espiromesifeno e tiametoxam sobre larvas de terceiro instar de C. externa, a fim de compatilizar os métodos biológico e quimíco no manejo de pragas no tomateiro.Resumo PDF 1756-2

    Toxicidade de imidaclopride e tiametoxam a larvas de Chrysoperia externa (Neuroptera: Chrysopidae) em condições de casa-de-vegetação.

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    Objetivou-se no presente trabalho mensurar o impacto dos inseticidas imidaclopride e tiametoxam, utilizados no controle da mosca-branca Bemisia tabaci tiótipo B (Hemiptera: Aleyrodidae) na cultura do tomateiro, sobre larvas de primeiro, segundo e terceiro instares de Chrysoperla externa, bem como sobre as fases subsequentes de seu desenvolvimento e sobre a reprodução de adultos oriundos de larvas tratadas.Resumo PDF 1736-

    Incidence, risk factors, and outcomes of second neoplasms in patients with acute promyelocytic leukemia:the PETHEMA-PALG experience

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    The most important challenges in acute promyelocytic leukemia (APL) is preventing early death and reducing long-term events, such as second neoplasms (s-NPLs). We performed a retrospective analysis of 2670 unselected APL patients, treated with PETHEMA “chemotherapy based” and “chemotherapy free” protocols. Only de novo APL patients who achieved complete remission (CR) and completed the three consolidation cycles were enrolled into the analysis. Out of 2670 APL patients, there were 118 (4.4%) who developed s-NPLs with the median latency period (between first CR and diagnosis of s-NPL) of 48.0 months (range 2.8–231.1): 43.3 (range: 2.8–113.9) for s-MDS/AML and 61.7 (range: 7.1–231.1) for solid tumour. The 5-year CI of all s-NPLs was of 4.43% and 10 years of 7.92%. Among s-NPLs, there were 58 cases of s-MDS/AML, 3 cases of other hematological neoplasms, 57 solid tumours and 1 non-identified neoplasm. The most frequent solid tumour was colorectal, lung and breast cancer. Overall, the 2-year OS from diagnosis of s-NPLs was 40.6%, with a median OS of 11.1 months. Multivariate analysis identified age of 35 years (hazard ratio = 0.2584; p &lt; 0.0001) as an independent prognostic factor for s-NPLs. There were no significant differences in CI of s-NPLs at 5 years between chemotherapy-based vs chemotherapy-free regimens (hazard ratio = 1.09; p = 0.932). Larger series with longer follow-up are required to confirm the potential impact of ATO+ATRA regimens to reduce the incidence of s-NPLs after front-line therapy for APL.</p
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