Revue actuelle en matière de leishmaniose canine

Revue actuelle en matière de leishmaniose canin

Performance and stability of a field fibre optics current sensor

Performance and stability of a field fibre optics interferometric current sensor are presented, showing a ±0.5% accuracy over a broad temperature range and an excellent insensitivity to the sensing fibre positionin

Fatigue Life Prediction of Welded Joint by Microstructure-based Simulation

This paper proposes a numerical framework to predict fatigue life on welded joints by integrating several computational techniques. The framework consists of five steps: i) materials properties estimation; ii) welding simulation using thermo-mechanical finite element method; iii) macroscopic stress field analysis under cyclic loading; iv) mesoscopic stress field analysis using crystal plasticity finite element method (CPFEM); v) analysis of fatigue crack growth. The total number of cycles to failure is eventually obtained by the sum of initiation life calculated by CPFEM and propagation life calculated by X-FEM. A fatigue life of butt joint is evaluated by the proposed method. The results demonstrated the possibility of evaluating the fatigue life and its scattering by the proposed framework

構造用鋼の疲労性能予測のための微細構造を考慮したモデリング

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 榎 学, 東京大学教授 小関 敏彦, 東京大学教授 佐藤 英一, 東京大学准教授 井上 純哉, 東京大学教授 酒井 信介University of Tokyo(東京大学

Extreme current measurements using a fibre optics current sensor

We demonstrate that an optical fibre current sensor can measure current over 500 kA with an accuracy of 0.2%. This level of accuracy has never previously been achieved using a traditional non-optical senso

A reconstruction technique for long-range stimulated Brillouin scattering distributed fibre-optic sensors: Experimental results

The experimental validation of a numerical technique for temperature/strain profile reconstruction based on Brillouin optical-fibre time-domain analysis (BOTDA) sensors is presented. In this approach, we search directly for the Brillouin frequency shift profile along the fibre that matches the measured data. The algorithm is based on a harmonic expansion of the unknown profile, whose coefficients are determined by means of a multidimensional minimization. Experimental measurements have been carried out in order to reveal the influence of nonlocalities in Brillouin measurements, and to prove the capability of the proposed algorithm to compensate for these effect

Using global existing fiber networks for environmental sensing

We review recent advances in distributed fiber optic sensing (DFOS) and their applications. The scattering mechanisms in glass, which are exploited for reflectometry-based DFOS, are Rayleigh, Brillouin, and Raman scatterings. These are sensitive to either strain and/or temperature, allowing optical fiber cables to monitor their ambient environment in addition to their conventional role as a medium for telecommunications. Recently, DFOS leveraged technologies developed for telecommunications, such as coherent detection, digital signal processing, coding, and spatial/frequency diversity, to achieve improved performance in terms of measurand resolution, reach, spatial resolution, and bandwidth. We review the theory and architecture of commonly used DFOS methods. We provide recent experimental and field trial results where DFOS was used in wide-ranging applications, such as geohazard monitoring, seismic monitoring, traffic monitoring, and infrastructure health monitoring. Events of interest often have unique signatures either in the spatial, temporal, frequency, or wavenumber domains. Based on the temperature and strain raw data obtained from DFOS, downstream postprocessing allows the detection, classification, and localization of events. Combining DFOS with machine learning methods, it is possible to realize complete sensor systems that are compact, low cost, and can operate in harsh environments and difficult-to-access locations, facilitating increased public safety and smarter cities

Hyper-IgG4 disease: report and characterisation of a new disease

BACKGROUND: We highlight a chronic inflammatory disease we call 'hyper-IgG4 disease', which has many synonyms depending on the organ involved, the country of origin and the year of the report. It is characterized histologically by a lymphoplasmacytic inflammation with IgG4-positive cells and exuberant fibrosis, which leaves dense fibrosis on resolution. A typical example is idiopathic retroperitoneal fibrosis, but the initial report in 2001 was of sclerosing pancreatitis. METHODS: We report an index case with fever and severe systemic disease. We have also reviewed the histology of 11 further patients with idiopathic retroperitoneal fibrosis for evidence of IgG4-expressing plasma cells, and examined a wide range of other inflammatory conditions and fibrotic diseases as organ-specific controls. We have reviewed the published literature for disease associations with idiopathic, systemic fibrosing conditions and the synonyms: pseudotumour, myofibroblastic tumour, plasma cell granuloma, systemic fibrosis, xanthofibrogranulomatosis, and multifocal fibrosclerosis. RESULTS: Histology from all 12 patients showed, to varying degrees, fibrosis, intense inflammatory cell infiltration with lymphocytes, plasma cells, scattered neutrophils, and sometimes eosinophilic aggregates, with venulitis and obliterative arteritis. The majority of lymphocytes were T cells that expressed CD8 and CD4, with scattered B-cell-rich small lymphoid follicles. In all cases, there was a significant increase in IgG4-positive plasma cells compared with controls. In two cases, biopsies before and after steroid treatment were available, and only scattered plasma cells were seen after treatment, none of them expressing IgG4. Review of the literature shows that although pathology commonly appears confined to one organ, patients can have systemic symptoms and fever. In the active period, there is an acute phase response with a high serum concentration of IgG, and during this phase, there is a rapid clinical response to glucocorticoid steroid treatment. CONCLUSION: We believe that hyper-IgG4 disease is an important condition to recognise, as the diagnosis can be readily verified and the outcome with treatment is very good